Increased Expression of Antioxidant and Antiapoptotic Genes in Islets That May Contribute to β-Cell Survival During Chronic Hyperglycemia

D. Ross Laybutt; Hideaki Kaneto; Wendy Hasenkamp; Shane Grey; Jean-Christophe Jonas; Dennis C. Sgroi; Adam Groff; Christiane Ferran; Susan Bonner-Weir; Arun Sharma; Gordon C. Weir

doi:10.2337/diabetes.51.2.413

Islet Studies

Increased Expression of Antioxidant and Antiapoptotic Genes in Islets That May Contribute to β-Cell Survival During Chronic Hyperglycemia

D. Ross Laybutt1,
Hideaki Kaneto1,
Wendy Hasenkamp1,
Shane Grey2,
Jean-Christophe Jonas1,
Dennis C. Sgroi3,
Adam Groff1,
Christiane Ferran2,
Susan Bonner-Weir1,
Arun Sharma1 and
Gordon C. Weir1

¹Section of Islet Transplantation and Cell Biology, Joslin Diabetes Center, Boston, Massachusetts
²Immunobiology Research Center, Beth Israel Deaconess Medical Center, Boston, Massachusetts
³Molecular Pathology Unit, Massachusetts General Hospital, Boston, Massachusetts

Diabetes 2002 Feb; 51(2): 413-423. https://doi.org/10.2337/diabetes.51.2.413

Article Information

vol. 51 no. 2 413-423

DOI

https://doi.org/10.2337/diabetes.51.2.413

PubMed

11812749

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

Published in print February 1, 2002.

Author Information

D. Ross Laybutt1,
Hideaki Kaneto1,
Wendy Hasenkamp1,
Shane Grey2,
Jean-Christophe Jonas1,
Dennis C. Sgroi3,
Adam Groff1,
Christiane Ferran2,
Susan Bonner-Weir1,
Arun Sharma1 and
Gordon C. Weir1

¹Section of Islet Transplantation and Cell Biology, Joslin Diabetes Center, Boston, Massachusetts
²Immunobiology Research Center, Beth Israel Deaconess Medical Center, Boston, Massachusetts
³Molecular Pathology Unit, Massachusetts General Hospital, Boston, Massachusetts

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