Early Decrease of Skin Blood Flow in Response to Locally Applied Pressure in Diabetic Subjects
Article Figures & Tables
Figures
- FIG. 1.
Means ± SE of skin blood flow measured with laser Doppler flowmetry during progressive 5.0 mmHg/min local pressure increase in diabetic patients without neuropathy (○) and control subjects (•) in usual ambient temperature. The mean skin temperatures were 29.3 ± 0.4 and 28.7 ± 0.4°C, respectively. Data are expressed as arbitrary units.
Tables
- TABLE 1
Characteristics of study subjects
Neuropathic patients Subclinical neuropathic patients Nonneuropathic patients Control subjects n 15 15 15 15 Age (years) 50 ± 3 58 ± 4 40 ± 3 47 ± 2 Men/women 8/7 11/4 8/7 7/8 Type of diabetes (1/2) 5/10 8/7 9/6 — Diabetes duration (years) 13.1 ± 2.6 11.9 ± 2.9 7.2 ± 2.0 — Height (cm) 167 ± 2 168 ± 2 166 ± 2 172 ± 3 Weight (kg) 77 ± 4 73 ± 2 66 ± 4 67 ± 3 Glycemia (g/l) 1.6 ± 0.2 1.3 ± 0.1 1.6 ± 0.2 — TcPO2 Forearm (mmHg) 69 ± 3 64 ± 3 68 ± 3 69 ± 2 Foot (mmHg) 64 ± 4 62 ± 4 64 ± 3 65 ± 3 Data are means ± SE.
- TABLE 2
Results of the assessment of neuropathy
Neuropathic patients Subclinical neuropathic patients Nonneuropathic patients Control subjects Neuropathy symptom score 2.1 ± 0.7 0.7 ± 0.2 0 ± 0 0 ± 0 Neuropathy disability score 8.7 ± 1.4 2.2 ± 0.5 0 ± 0 0 ± 0 Semmes-Weinstein monofilaments (g) 3.8 ± 0.1† 3.7 ± 0.2* 2.7 ± 0.1 3.1 ± 0.2 Neurothesiometer (a.u.) 20.4 ± 4.7‡ 16.8 ± 1.8‡ 8.8 ± 1.2 8.7 ± 0.9 Peroneal nerve conduction velocity (m/s) 38.6 ± 1.6 40.4 ± 0.7 44.9 ± 0.9 — Measurable velocities 8 (53) 8 (53) 13 (87) — Data are means ± SE or n (%).
- *
* P < 0.05 vs. control subjects;
- †
† P < 0.01 vs. control subjects;
- ‡
‡ P < 0.001 vs. control subjects.
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April 2002, 51(4)
Early Decrease of Skin Blood Flow in Response to Locally Applied Pressure in Diabetic Subjects
