Molecular Mechanisms of Insulin Resistance in IRS-2-Deficient Hepatocytes

Angela M. Valverde; Deborah J. Burks; Isabel Fabregat; Tracey L. Fisher; José Carretero; Morris F. White; Manuel Benito

doi:10.2337/diabetes.52.9.2239

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Molecular Mechanisms of Insulin Resistance in IRS-2-Deficient Hepatocytes

Angela M. Valverde, 1,
Deborah J. Burks2,
Isabel Fabregat1,
Tracey L. Fisher3,
José Carretero2,
Morris F. White3 and
Manuel Benito1

¹Instituto de Bioquímica/Departamento de Bioquímica y Biología Molecular II, Centro Mixto CSIC/UCM, Facultad de Farmacia, Universidad Complutense, Madrid, Spain
²Departamento de Anatomia, Facultad de Medicina, Campus Charro, Salamanca, Spain
³Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts

Address correspondence and reprint requests to Angela M. Valverde, Instituto de Bioquímica/Departamento de Bioquímica y Biología Molecular, Facultad de Farmacia, Ciudad Universitaria, 28040 Madrid, Spain. E-mail: valverde{at}farm.ucm.es

Diabetes 2003 Sep; 52(9): 2239-2248. https://doi.org/10.2337/diabetes.52.9.2239

Article Information

vol. 52 no. 9 2239-2248

DOI

https://doi.org/10.2337/diabetes.52.9.2239

PubMed

12941762

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

June 5, 2003
February 3, 2003
Published in print August 26, 2003.

DIABETES

Author Information

Angela M. Valverde, 1,
Deborah J. Burks2,
Isabel Fabregat1,
Tracey L. Fisher3,
José Carretero2,
Morris F. White3 and
Manuel Benito1

¹Instituto de Bioquímica/Departamento de Bioquímica y Biología Molecular II, Centro Mixto CSIC/UCM, Facultad de Farmacia, Universidad Complutense, Madrid, Spain
²Departamento de Anatomia, Facultad de Medicina, Campus Charro, Salamanca, Spain
³Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts

Address correspondence and reprint requests to Angela M. Valverde, Instituto de Bioquímica/Departamento de Bioquímica y Biología Molecular, Facultad de Farmacia, Ciudad Universitaria, 28040 Madrid, Spain. E-mail: valverde{at}farm.ucm.es

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