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Table of Contents

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December 01 2004; volume 53 issue 12

Perspectives in Diabetes

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    Age-Dependent Influences on the Origins of Autoimmune DiabetesEvidence and Implications
    R. David G. Leslie and Michela Delli Castelli
    Diabetes 2004 Dec; 53 (12): 3033-3040. https://doi.org/10.2337/diabetes.53.12.3033
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Metabolism

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    Exercise-Induced Changes in Insulin and Glucagon Are Not Required for Enhanced Hepatic Glucose Uptake After Exercise but Influence the Fate of Glucose Within the Liver
    R. Richard Pencek, Freyja D. James, D. Brooks Lacy, Kareem Jabbour, Phillip E. Williams, Patrick T. Fueger and David H. Wasserman
    Diabetes 2004 Dec; 53 (12): 3041-3047. https://doi.org/10.2337/diabetes.53.12.3041
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    Alterations in Postprandial Hepatic Glycogen Metabolism in Type 2 Diabetes
    Martin Krssak, Attila Brehm, Elisabeth Bernroider, Christian Anderwald, Peter Nowotny, Chiara Dalla Man, Claudio Cobelli, Gary W. Cline, Gerald I. Shulman, Werner Waldhäusl and Michael Roden
    Diabetes 2004 Dec; 53 (12): 3048-3056. https://doi.org/10.2337/diabetes.53.12.3048
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Signal Transduction

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    Hepatic PTP-1B Expression Regulates the Assembly and Secretion of Apolipoprotein B–Containing LipoproteinsEvidence From Protein Tyrosine Phosphatase-1B Overexpression, Knockout, and RNAi Studies
    Wei Qiu, Rita Kohen Avramoglu, Nadia Dubé, Taryne M. Chong, Mark Naples, Crystal Au, Konstantinos G. Sidiropoulos, Gary F. Lewis, Jeffrey S. Cohn, Michel L. Tremblay and Khosrow Adeli
    Diabetes 2004 Dec; 53 (12): 3057-3066. https://doi.org/10.2337/diabetes.53.12.3057
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    LRb-STAT3 Signaling Is Required for the Neuroendocrine Regulation of Energy Expenditure by Leptin
    Sarah H. Bates, Trevor A. Dundon, Matthew Seifert, Michael Carlson, Eleftheria Maratos-Flier and Martin G. Myers
    Diabetes 2004 Dec; 53 (12): 3067-3073. https://doi.org/10.2337/diabetes.53.12.3067
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    The α2–5′AMP-Activated Protein Kinase Is a Site 2 Glycogen Synthase Kinase in Skeletal Muscle and Is Responsive to Glucose Loading
    Sebastian B. Jørgensen, Jakob N. Nielsen, Jesper B. Birk, Grith Skytte Olsen, Benoit Viollet, Fabrizio Andreelli, Peter Schjerling, Sophie Vaulont, D. Grahame Hardie, Bo F. Hansen, Erik A. Richter and Jørgen F.P. Wojtaszewski
    Diabetes 2004 Dec; 53 (12): 3074-3081. https://doi.org/10.2337/diabetes.53.12.3074
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    G-Protein Signaling Participates in the Development of Diabetic Cardiomyopathy
    Ian S. Harris, Ilya Treskov, Michael W. Rowley, Scott Heximer, Kevin Kaltenbronn, Brian N. Finck, Richard W. Gross, Daniel P. Kelly, Kendall J. Blumer and Anthony J. Muslin
    Diabetes 2004 Dec; 53 (12): 3082-3090. https://doi.org/10.2337/diabetes.53.12.3082
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Obesity Study

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    Pancreatic Polypeptide Is Involved in the Regulation of Body Weight in Pima Indian Male Subjects
    Juraj Koska, Angelo DelParigi, Barbora de Courten, Christian Weyer and P. Antonio Tataranni
    Diabetes 2004 Dec; 53 (12): 3091-3096. https://doi.org/10.2337/diabetes.53.12.3091
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    Fibroblast Growth Factor 1A Key Regulator of Human Adipogenesis
    Louise Hutley, Wenda Shurety, Felicity Newell, Ross McGeary, Nicole Pelton, Jennifer Grant, Adrian Herington, Donald Cameron, Jon Whitehead and Johannes Prins
    Diabetes 2004 Dec; 53 (12): 3097-3106. https://doi.org/10.2337/diabetes.53.12.3097
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Immunology and Transplantation

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    Islet Graft Assessment in the Edmonton ProtocolImplications for Predicting Long-Term Clinical Outcome
    Cale N. Street, Jonathan R.T. Lakey, A.M. James Shapiro, Sharleen Imes, Ray V. Rajotte, Edmond A. Ryan, James G. Lyon, Tatsuya Kin, Jose Avila, Toshiaki Tsujimura and Gregory S. Korbutt
    Diabetes 2004 Dec; 53 (12): 3107-3114. https://doi.org/10.2337/diabetes.53.12.3107
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    Absence of Lymph Nodes in NOD Mice Treated With Lymphotoxin-β Receptor Immunoglobulin Protects From Diabetes
    Matteo G. Levisetti, Anish Suri, Katherine Frederick and Emil R. Unanue
    Diabetes 2004 Dec; 53 (12): 3115-3119. https://doi.org/10.2337/diabetes.53.12.3115
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Islet Study

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    Characterization of Mice Doubly Transgenic for Parathyroid Hormone-Related Protein and Murine Placental LactogenA Novel Role for Placental Lactogen in Pancreatic β-Cell Survival
    Yuichi Fujinaka, Darinka Sipula, Adolfo Garcia-Ocaña and Rupangi C. Vasavada
    Diabetes 2004 Dec; 53 (12): 3120-3130. https://doi.org/10.2337/diabetes.53.12.3120
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    Pancreatic-Specific Inactivation of IGF-I Gene Causes Enlarged Pancreatic Islets and Significant Resistance to Diabetes
    Yarong Lu, Pedro L. Herrera, Yubin Guo, David Sun, Zhengyi Tang, Derek LeRoith and Jun-Li Liu
    Diabetes 2004 Dec; 53 (12): 3131-3141. https://doi.org/10.2337/diabetes.53.12.3131
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    Endogenous Ghrelin in Pancreatic Islets Restricts Insulin Release by Attenuating Ca2+ Signaling in β-CellsImplication in the Glycemic Control in Rodents
    Katsuya Dezaki, Hiroshi Hosoda, Masafumi Kakei, Suzuko Hashiguchi, Masatomo Watanabe, Kenji Kangawa and Toshihiko Yada
    Diabetes 2004 Dec; 53 (12): 3142-3151. https://doi.org/10.2337/diabetes.53.12.3142
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    Massive Augmentation of Stimulated Insulin Secretion Induced by Fatty Acid–Free BSA in Rat Pancreatic Islets
    Susanne G. Straub and Geoffrey W. G. Sharp
    Diabetes 2004 Dec; 53 (12): 3152-3158. https://doi.org/10.2337/diabetes.53.12.3152
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    Diet-Induced Glucose Intolerance in Mice With Decreased β-Cell ATP-Sensitive K+ Channels
    Maria S. Remedi, Joseph. C. Koster, Kamelia Markova, Susumu Seino, Takashi Miki, Brian L. Patton, Michael L. McDaniel and Colin G. Nichols
    Diabetes 2004 Dec; 53 (12): 3159-3167. https://doi.org/10.2337/diabetes.53.12.3159
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    High Glucose Is Necessary for Complete Maturation of Pdx1-VP16–Expressing Hepatic Cells into Functional Insulin-Producing Cells
    Li-Zhen Cao, Dong-Qi Tang, Marko E. Horb, Shi-Wu Li and Li-Jun Yang
    Diabetes 2004 Dec; 53 (12): 3168-3178. https://doi.org/10.2337/diabetes.53.12.3168
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    Stimulation of Insulin Release by Glucose Is Associated With an Increase in the Number of Docked Granules in the β-Cells of Rat Pancreatic Islets
    Susanne G. Straub, Geetha Shanmugam and Geoffrey W.G. Sharp
    Diabetes 2004 Dec; 53 (12): 3179-3183. https://doi.org/10.2337/diabetes.53.12.3179
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Pathophysiology

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    Insulin Stimulates and Diabetes Inhibits O-Linked N-Acetylglucosamine Transferase and O-Glycosylation of Sp1
    Gipsy Majumdar, Jeremiah Wright, Paul Markowitz, Antonio Martinez-Hernandez, Rajendra Raghow and Solomon S. Solomon
    Diabetes 2004 Dec; 53 (12): 3184-3192. https://doi.org/10.2337/diabetes.53.12.3184
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    Phenotypic Characteristics of GAD Antibody-Positive Recently Diagnosed Patients With Type 2 Diabetes in North America and Europe
    Bernard Zinman, Steven E. Kahn, Steven M. Haffner, M. Colleen O’Neill, Mark A. Heise and Martin I. Freed
    Diabetes 2004 Dec; 53 (12): 3193-3200. https://doi.org/10.2337/diabetes.53.12.3193
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    Decreased Sarcoplasmic Reticulum Activity and Contractility in Diabetic db/db Mouse Heart
    Darrell D. Belke, Eric A. Swanson and Wolfgang H. Dillmann
    Diabetes 2004 Dec; 53 (12): 3201-3208. https://doi.org/10.2337/diabetes.53.12.3201
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    Palmitate-Induced Interleukin-6 Expression in Human Coronary Artery Endothelial Cells
    Harald Staiger, Katrin Staiger, Norbert Stefan, Hans Günther Wahl, Fausto Machicao, Monika Kellerer and Hans-Ulrich Häring
    Diabetes 2004 Dec; 53 (12): 3209-3216. https://doi.org/10.2337/diabetes.53.12.3209
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Complication

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    Hyperlipidemia in Concert With Hyperglycemia Stimulates the Proliferation of Macrophages in Atherosclerotic LesionsPotential Role of Glucose-Oxidized LDL
    Najib Lamharzi, Catherine B. Renard, Farah Kramer, Subramaniam Pennathur, Jay W. Heinecke, Alan Chait and Karin E. Bornfeldt
    Diabetes 2004 Dec; 53 (12): 3217-3225. https://doi.org/10.2337/diabetes.53.12.3217
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    Hyperglycemia Regulates Hypoxia-Inducible Factor-1α Protein Stability and Function
    Sergiu-Bogdan Catrina, Kensaku Okamoto, Teresa Pereira, Kerstin Brismar and Lorenz Poellinger
    Diabetes 2004 Dec; 53 (12): 3226-3232. https://doi.org/10.2337/diabetes.53.12.3226
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    Effect of Long-Term Administration of α-Lipoic Acid on Retinal Capillary Cell Death and the Development of Retinopathy in Diabetic Rats
    Renu A. Kowluru and Sarah Odenbach
    Diabetes 2004 Dec; 53 (12): 3233-3238. https://doi.org/10.2337/diabetes.53.12.3233
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    Effects of Polyol Pathway Hyperactivity on Protein Kinase C Activity, Nociceptive Peptide Expression, and Neuronal Structure in Dorsal Root Ganglia in Diabetic Mice
    Kenji Uehara, Shin-Ichiro Yamagishi, Saori Otsuki, Shyunsuke Chin and Soroku Yagihashi
    Diabetes 2004 Dec; 53 (12): 3239-3247. https://doi.org/10.2337/diabetes.53.12.3239
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    Development of Late-Stage Diabetic Nephropathy in OVE26 Diabetic Mice
    Shirong Zheng, William T. Noonan, Naira S. Metreveli, Susan Coventry, Patricia M. Kralik, Edward C. Carlson and Paul N. Epstein
    Diabetes 2004 Dec; 53 (12): 3248-3257. https://doi.org/10.2337/diabetes.53.12.3248
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Pharmacology & Therapeutic

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    Metformin Prevents the Development of Acute Lipid-Induced Insulin Resistance in the Rat Through Altered Hepatic Signaling Mechanisms
    Mark E. Cleasby, Nicolas Dzamko, Bronwyn D. Hegarty, Gregory J. Cooney, Edward W. Kraegen and Ji-Ming Ye
    Diabetes 2004 Dec; 53 (12): 3258-3266. https://doi.org/10.2337/diabetes.53.12.3258
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    A Novel Glucagon Receptor Antagonist Inhibits Glucagon-Mediated Biological Effects
    Sajjad A. Qureshi, Mari Rios Candelore, Dan Xie, Xiaodong Yang, Laurie M. Tota, Victor D.-H. Ding, Zhihua Li, Alka Bansal, Corin Miller, Sheila M. Cohen, Guoqiang Jiang, Ed Brady, Richard Saperstein, Joseph L. Duffy, James R. Tata, Kevin T. Chapman, David E. Moller and Bei B. Zhang
    Diabetes 2004 Dec; 53 (12): 3267-3273. https://doi.org/10.2337/diabetes.53.12.3267
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Genetic

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    Genetic Determinants of Energy Expenditure and Insulin Resistance in Diet-Induced Obesity in Mice
    Katrine Almind and C. Ronald Kahn
    Diabetes 2004 Dec; 53 (12): 3274-3285. https://doi.org/10.2337/diabetes.53.12.3274
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    Heterogeneity in the Magnitude of the Insulin Gene Effect on HLA Risk in Type 1 Diabetes
    Costantino Motzo, Daniela Contu, Heather J. Cordell, Rosanna Lampis, Mauro Congia, Maria Giovanna Marrosu, John A. Todd, Marcella Devoto and Francesco Cucca
    Diabetes 2004 Dec; 53 (12): 3286-3291. https://doi.org/10.2337/diabetes.53.12.3286
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    Polymorphism in the Calsequestrin 1 (CASQ1) Gene on Chromosome 1q21 Is Associated With Type 2 Diabetes in the Old Order Amish
    Mao Fu, Coleen M. Damcott, Mona Sabra, Toni I. Pollin, Sandra H. Ott, Jian Wang, Michael J. Garant, Jeffrey R. O’Connell, Braxton D. Mitchell and Alan R. Shuldiner
    Diabetes 2004 Dec; 53 (12): 3292-3299. https://doi.org/10.2337/diabetes.53.12.3292
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Brief Genetic Report

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    Calsquestrin 1 (CASQ1) Gene Polymorphisms Under Chromosome 1q21 Linkage Peak Are Associated With Type 2 Diabetes in Northern European Caucasians
    Swapan Kumar Das, Winston Chu, Zhengxian Zhang, Sandra J. Hasstedt and Steven C. Elbein
    Diabetes 2004 Dec; 53 (12): 3300-3306. https://doi.org/10.2337/diabetes.53.12.3300
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    Linkage Analysis of Diabetes Status Among Hypertensive FamiliesThe Hypertension Genetic Epidemiology Network Study
    Christy L. Avery, Barry I. Freedman, Gerardo Heiss, Aldi Kraja, Treva Rice, Donna Arnett, Michael B. Miller, James S. Pankow, Cora E. Lewis, Richard H. Myers, Steven C. Hunt, Laura Almasy and Kari E. North
    Diabetes 2004 Dec; 53 (12): 3307-3312. https://doi.org/10.2337/diabetes.53.12.3307
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    Association Testing in 9,000 People Fails to Confirm the Association of the Insulin Receptor Substrate-1 G972R Polymorphism With Type 2 Diabetes
    Jose C. Florez, Marketa Sjögren, Noël Burtt, Marju Orho-Melander, Steve Schayer, Maria Sun, Peter Almgren, Ulf Lindblad, Tiinamaija Tuomi, Daniel Gaudet, Thomas J. Hudson, Mark J. Daly, Kristin G. Ardlie, Joel N. Hirschhorn, David Altshuler and Leif Groop
    Diabetes 2004 Dec; 53 (12): 3313-3318. https://doi.org/10.2337/diabetes.53.12.3313
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    Association Studies of Insulin Receptor Substrate 1 Gene (IRS1) Variants in Type 2 Diabetes Samples Enriched for Family History and Early Age of Onset
    Eleftheria Zeggini, James Parkinson, Stephanie Halford, Katharine R. Owen, Timothy M. Frayling, Mark Walker, Graham A. Hitman, Jonathan C. Levy, Mike J. Sampson, Edith J.M. Feskens, Andrew T. Hattersley and Mark I. McCarthy
    Diabetes 2004 Dec; 53 (12): 3319-3322. https://doi.org/10.2337/diabetes.53.12.3319
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    Mapping Non–Class II H2-Linked Loci for Type 1 Diabetes in Nonobese Diabetic Mice
    Nathalie Deruytter, Olivier Boulard and Henri-Jean Garchon
    Diabetes 2004 Dec; 53 (12): 3323-3327. https://doi.org/10.2337/diabetes.53.12.3323
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    Quantitative Trait Loci for Obesity- and Diabetes-Related Traits and Their Dietary Responses to High-Fat Feeding in LGXSM Recombinant Inbred Mouse Strains
    James M. Cheverud, Thomas H. Ehrich, Tomas Hrbek, Jane P. Kenney, L. Susan Pletscher and Clay F. Semenkovich
    Diabetes 2004 Dec; 53 (12): 3328-3336. https://doi.org/10.2337/diabetes.53.12.3328
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    Polymorphisms in Both Promoters of Hepatocyte Nuclear Factor 4-α Are Associated With Type 2 Diabetes in the Amish
    Coleen M. Damcott, Nicole Hoppman, Sandra H. Ott, Laurie J. Reinhart, Jian Wang, Toni I. Pollin, Jeffrey R. O’Connell, Braxton D. Mitchell and Alan R. Shuldiner
    Diabetes 2004 Dec; 53 (12): 3337-3341. https://doi.org/10.2337/diabetes.53.12.3337
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    Variation in the Interleukin-6 Receptor Gene Associates With Type 2 Diabetes in Danish Whites
    Yasmin H. Hamid, Søren A. Urhammer, Dorit P. Jensen, Charlotte Glümer, Knut Borch-Johnsen, Torben Jørgensen, Torben Hansen and Oluf Pedersen
    Diabetes 2004 Dec; 53 (12): 3342-3345. https://doi.org/10.2337/diabetes.53.12.3342
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December 2004, 53(12)
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