Diabetes: 53 (3)

March 01 2004; volume 53 issue 3

Perspectives in Diabetes

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Transcriptional Control of Apolipoprotein A-I Gene Expression in Diabetes
Arshag D. Mooradian, Michael J. Haas and Norman C.W. Wong

Diabetes 2004 Mar; 53 (3): 513-520. https://doi.org/10.2337/diabetes.53.3.513

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Metabolism

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Systemic and Forearm Triglyceride MetabolismFate of Lipoprotein Lipase-Generated Glycerol and Free Fatty Acids
John M. Miles, Yongsoon S. Park, Dorota Walewicz, Crystal Russell-Lopez, Sheryl Windsor, William L. Isley, Simon W. Coppack and William S. Harris

Diabetes 2004 Mar; 53 (3): 521-527. https://doi.org/10.2337/diabetes.53.3.521

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Muscle-Type Specific Intramyocellular and Hepatic Lipid Metabolism During Starvation in Wistar Rats
Claudia Neumann-Haefelin, Anja Beha, Johanna Kuhlmann, Ulrich Belz, Martin Gerl, Manfred Quint, Gabriele Biemer-Daub, Mark Broenstrup, Marion Stein, Elke Kleinschmidt, Hans-Ludwig Schaefer, Dieter Schmoll, Werner Kramer, Hans-Paul Juretschke and Andreas W. Herling

Diabetes 2004 Mar; 53 (3): 528-534. https://doi.org/10.2337/diabetes.53.3.528

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Stimulation of Hepatocyte Glucose Metabolism by Novel Small Molecule Glucokinase Activators
Katy J. Brocklehurst, Victoria A. Payne, Rick A. Davies, Debra Carroll, Helen L. Vertigan, Heather J. Wightman, Susan Aiston, Ian D. Waddell, Brendan Leighton, Matthew P. Coghlan and Loranne Agius

Diabetes 2004 Mar; 53 (3): 535-541. https://doi.org/10.2337/diabetes.53.3.535

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Reduced Lipid Oxidation in Skeletal Muscle From Type 2 Diabetic Subjects May Be of Genetic OriginEvidence From Cultured Myotubes
Michael Gaster, Arild C. Rustan, Vigdis Aas and Henning Beck-Nielsen

Diabetes 2004 Mar; 53 (3): 542-548. https://doi.org/10.2337/diabetes.53.3.542

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Signal Transduction

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Physiological and Molecular Characteristics of Rat Hypothalamic Ventromedial Nucleus Glucosensing Neurons
Ling Kang, Vanessa H. Routh, Eldo V. Kuzhikandathil, Larry D. Gaspers and Barry E. Levin

Diabetes 2004 Mar; 53 (3): 549-559. https://doi.org/10.2337/diabetes.53.3.549

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Insulin-Independent Induction of Sterol Regulatory Element-Binding Protein-1c Expression in the Livers of Streptozotocin-Treated Mice
Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi, Michiyo Amemiya-Kudo, Hiroaki Okazaki, Yoshiaki Tamura, Yoko Iizuka, Ken Ohashi, Sachiko Tomita, Motohiro Sekiya, Alyssa Hasty, Yoshimi Nakagawa, Hirohito Sone, Hideo Toyoshima, Shun Ishibashi, Jun-ichi Osuga and Nobuhiro Yamada

Diabetes 2004 Mar; 53 (3): 560-569. https://doi.org/10.2337/diabetes.53.3.560

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Obesity Study

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Leptin Resistance and Enhancement of Feeding Facilitation by Melanin-Concentrating Hormone in Mice Lacking Bombesin Receptor Subtype-3
Fumihiko Maekawa, Hun-Meng A. Quah, Kohichi Tanaka and Hiroko Ohki-Hamazaki

Diabetes 2004 Mar; 53 (3): 570-576. https://doi.org/10.2337/diabetes.53.3.570

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Mice with Targeted Disruption of the Dio2 Gene Have Cold-Induced Overexpression of the Uncoupling Protein 1 Gene but Fail to Increase Brown Adipose Tissue Lipogenesis and Adaptive Thermogenesis
Marcelo A. Christoffolete, Camila C.G. Linardi, Lucia de Jesus, Katia Naomi Ebina, Suzy D. Carvalho, Miriam O. Ribeiro, Rogerio Rabelo, Cyntia Curcio, Luciane Martins, Edna T. Kimura and Antonio C. Bianco

Diabetes 2004 Mar; 53 (3): 577-584. https://doi.org/10.2337/diabetes.53.3.577

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Discrimination Between Obesity and Insulin Resistance in the Relationship With Adiponectin
Fahim Abbasi, James W. Chu, Cindy Lamendola, Tracey McLaughlin, John Hayden, Gerald M. Reaven and Peter D. Reaven

Diabetes 2004 Mar; 53 (3): 585-590. https://doi.org/10.2337/diabetes.53.3.585

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Immunology

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Virally Induced Inflammation Triggers Fratricide of Fas-Ligand–Expressing β-Cells
Urs Christen, Rima Darwiche, Helen E. Thomas, Tom Wolfe, Evelyn Rodrigo, Alexander Chervonsky, Richard A. Flavell and Matthias G. von Herrath

Diabetes 2004 Mar; 53 (3): 591-596. https://doi.org/10.2337/diabetes.53.3.591

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Islet Study

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Expression of Voltage-Gated Potassium Channels in Human and Rhesus Pancreatic Islets
Lizhen Yan, David J. Figueroa, Christopher P. Austin, Yuan Liu, Randal M. Bugianesi, Robert S. Slaughter, Gregory J. Kaczorowski and Martin G. Kohler

Diabetes 2004 Mar; 53 (3): 597-607. https://doi.org/10.2337/diabetes.53.3.597

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Activin A and BetacellulinEffect on Regeneration of Pancreatic β-Cells in Neonatal Streptozotocin-Treated Rats
Lei Li, Zhaohong Yi, Masaharu Seno and Itaru Kojima

Diabetes 2004 Mar; 53 (3): 608-615. https://doi.org/10.2337/diabetes.53.3.608

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No Evidence for Significant Transdifferentiation of Bone Marrow Into Pancreatic β-Cells In Vivo
Andreas Lechner, Yong-Guang Yang, Robyn A. Blacken, Lan Wang, Anna L. Nolan and Joel F. Habener

Diabetes 2004 Mar; 53 (3): 616-623. https://doi.org/10.2337/diabetes.53.3.616

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Structural and Functional Abnormalities in the Islets Isolated From Type 2 Diabetic Subjects
Shaoping Deng, Marko Vatamaniuk, Xiaolun Huang, Nicolai Doliba, Moh-Moh Lian, Adam Frank, Ergun Velidedeoglu, Niraj M. Desai, Brigitte Koeberlein, Bryan Wolf, Clyde F. Barker, Ali Naji, Franz M. Matschinsky and James F. Markmann

Diabetes 2004 Mar; 53 (3): 624-632. https://doi.org/10.2337/diabetes.53.3.624

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Pathophysiology

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Consequences on β-Cell Function and Reserve After Long-Term Pancreas Transplantation
R. Paul Robertson

Diabetes 2004 Mar; 53 (3): 633-644. https://doi.org/10.2337/diabetes.53.3.633

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Ketosis-Prone Type 2 Diabetes in Patients of Sub-Saharan African OriginClinical Pathophysiology and Natural History of β-Cell Dysfunction and Insulin Resistance
Franck Mauvais-Jarvis, Eugène Sobngwi, Raphaël Porcher, Jean-Pierre Riveline, Jean-Philippe Kevorkian, Christian Vaisse, Guillaume Charpentier, Pierre-Jean Guillausseau, Patrick Vexiau and Jean-François Gautier

Diabetes 2004 Mar; 53 (3): 645-653. https://doi.org/10.2337/diabetes.53.3.645

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Secretion, Degradation, and Elimination of Glucagon-Like Peptide 1 and Gastric Inhibitory Polypeptide in Patients with Chronic Renal Insufficiency and Healthy Control Subjects
Juris J. Meier, Michael A. Nauck, Daniel Kranz, Jens J. Holst, Carolyn F. Deacon, Dirk Gaeckler, Wolfgang E. Schmidt and Baptist Gallwitz

Diabetes 2004 Mar; 53 (3): 654-662. https://doi.org/10.2337/diabetes.53.3.654

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Parasympathetic Blockade Attenuates Augmented Pancreatic Polypeptide But Not Insulin Secretion in Pima Indians
Barbora Vozarova de Courten, Christian Weyer, Norbert Stefan, Mark Horton, Angelo DelParigi, Peter Havel, Clifton Bogardus and P. Antonio Tataranni

Diabetes 2004 Mar; 53 (3): 663-671. https://doi.org/10.2337/diabetes.53.3.663

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In Vitro Transcriptional Induction of the Human Apolipoprotein A-II Gene by Glucose
Dominique Sauvaget, Valérie Chauffeton, Sonia Dugué-Pujol, Athina-Despina Kalopissis, Isabelle Guillet-Deniau, Fabienne Foufelle, Jean Chambaz, Armelle Leturque, Philippe Cardot and Agnès Ribeiro

Diabetes 2004 Mar; 53 (3): 672-678. https://doi.org/10.2337/diabetes.53.3.672

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The Effects of Dehydroepiandrosterone Sulfate on Counterregulatory Responses During Repeated Hypoglycemia in Conscious Normal Rats
Darleen A. Sandoval, Ling Ping, Ray Anthony Neill, Sachiko Morrey and Stephen N. Davis

Diabetes 2004 Mar; 53 (3): 679-686. https://doi.org/10.2337/diabetes.53.3.679

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Magnetic Resonance Imaging of the Brain in DiabetesThe Cardiovascular Determinants of Dementia (CASCADE) Study
Reinhold Schmidt, Lenore J. Launer, Lars-Göran Nilsson, Andrzej Pajak, Susanna Sans, Klaus Berger, Monique M. Breteler, Maria de Ridder, Carole Dufouil, Rebecca Fuhrer, Simona Giampaoli and Albert Hofman

Diabetes 2004 Mar; 53 (3): 687-692. https://doi.org/10.2337/diabetes.53.3.687

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Inflammatory Markers and Risk of Developing Type 2 Diabetes in Women
Frank B. Hu, James B. Meigs, Tricia Y. Li, Nader Rifai and JoAnn E. Manson

Diabetes 2004 Mar; 53 (3): 693-700. https://doi.org/10.2337/diabetes.53.3.693

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Effect of Postprandial Hypertriglyceridemia and Hyperglycemia on Circulating Adhesion Molecules and Oxidative Stress Generation and the Possible Role of Simvastatin Treatment
Antoniom Ceriello, Lisa Quagliaro, Ludovica Piconi, Roberta Assaloni, Roberto Da Ros, Amabile Maier, Katherine Esposito and Dario Giugliano

Diabetes 2004 Mar; 53 (3): 701-710. https://doi.org/10.2337/diabetes.53.3.701

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Complication

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Role of Poly(ADP-Ribose) Polymerase Activation in Diabetic Neuropathy
Irina G. Obrosova, Fei Li, Omorodola I. Abatan, Mark A. Forsell, Katalin Komjáti, Pal Pacher, Csaba Szabó and Martin J. Stevens

Diabetes 2004 Mar; 53 (3): 711-720. https://doi.org/10.2337/diabetes.53.3.711

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Impaired Pressure-Induced Vasodilation at the Foot in Young Adults With Type 1 Diabetes
Audrey Koı̈tka, Pierre Abraham, Beatrice Bouhanick, Dominique Sigaudo-Roussel, Claire Demiot and Jean Louis Saumet

Diabetes 2004 Mar; 53 (3): 721-725. https://doi.org/10.2337/diabetes.53.3.721

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Uncoupling Proteins Prevent Glucose-Induced Neuronal Oxidative Stress and Programmed Cell Death
Andrea M. Vincent, James A. Olzmann, Michael Brownlee, W.I. Sivitz and James W. Russell

Diabetes 2004 Mar; 53 (3): 726-734. https://doi.org/10.2337/diabetes.53.3.726

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Initial Characterization of a Rat Model of Diabetic Nephropathy
Marcelo A. Nobrega, Stewart Fleming, Richard J. Roman, Masahide Shiozawa, Nancy Schlick, Jozef Lazar and Howard J. Jacob

Diabetes 2004 Mar; 53 (3): 735-742. https://doi.org/10.2337/diabetes.53.3.735

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Divergent Pathways of Gene Expression Are Activated by the RAGE Ligands S100b and AGE-BSA
Jessica V. Valencia, Manisha Mone, Jin Zhang, Marla Weetall, Frank P. Buxton and Thomas E. Hughes

Diabetes 2004 Mar; 53 (3): 743-751. https://doi.org/10.2337/diabetes.53.3.743

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Hyperglycemia-Induced Defects in Angiogenesis in the Chicken Chorioallantoic Membrane Model
Etienne Larger, Michel Marre, Pierre Corvol and Jean-Marie Gasc

Diabetes 2004 Mar; 53 (3): 752-761. https://doi.org/10.2337/diabetes.53.3.752

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Attenuation of Renal Injury in db/db Mice Overexpressing Superoxide DismutaseEvidence for Reduced Superoxide−Nitric Oxide Interaction
Frederick R. DeRubertis, Patricia A. Craven, Mona F. Melhem and Eman M. Salah

Diabetes 2004 Mar; 53 (3): 762-768. https://doi.org/10.2337/diabetes.53.3.762

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Electrically Stimulated Axon Reflexes Are Diminished in Diabetic Small Fiber Neuropathies
Heidrun H. Krämer, Martin Schmelz, Frank Birklein and Andreas Bickel

Diabetes 2004 Mar; 53 (3): 769-774. https://doi.org/10.2337/diabetes.53.3.769

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Potential Contributory Role of H-Ras, a Small G-Protein, in the Development of Retinopathy in Diabetic Rats
Renu A. Kowluru, Anjaneyulu Kowluru, Subrata Chakrabarti and Zia Khan

Diabetes 2004 Mar; 53 (3): 775-783. https://doi.org/10.2337/diabetes.53.3.775

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Molecular Profiling of Diabetic Mouse Kidney Reveals Novel Genes Linked to Glomerular Disease
Katalin Susztak, Erwin Böttinger, Akiva Novetsky, Dan Liang, Yanqing Zhu, Emilio Ciccone, Dona Wu, Stephen Dunn, Peter McCue and Kumar Sharma

Diabetes 2004 Mar; 53 (3): 784-794. https://doi.org/10.2337/diabetes.53.3.784

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Molecular Mechanisms of High Glucose-Induced Cyclooxygenase-2 Expression in Monocytes
Narkunaraja Shanmugam, Irene T. Gaw Gonzalo and Rama Natarajan

Diabetes 2004 Mar; 53 (3): 795-802. https://doi.org/10.2337/diabetes.53.3.795

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Genetics

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A Genome-Wide Scan for Childhood Obesity–Associated Traits in French Families Shows Significant Linkage on Chromosome 6q22.31-q23.2
David Meyre, Cécile Lecoeur, Jérôme Delplanque, Stephan Francke, Vincent Vatin, Emmanuelle Durand, Jacques Weill, Christian Dina and Philippe Froguel

Diabetes 2004 Mar; 53 (3): 803-811. https://doi.org/10.2337/diabetes.53.3.803

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An Obesity-Related Locus in Chromosome Region 12q23-24
Wei-Dong Li, Chuanhui Dong, Ding Li, Hongyu Zhao and R. Arlen Price

Diabetes 2004 Mar; 53 (3): 812-820. https://doi.org/10.2337/diabetes.53.3.812

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A Large Set of Finnish Affected Sibling Pair Families With Type 2 Diabetes Suggests Susceptibility Loci on Chromosomes 6, 11, and 14
Kaisa Silander, Laura J. Scott, Timo T. Valle, Karen L. Mohlke, Heather M. Stringham, Kerry R. Wiles, William L. Duren, Kimberly F. Doheny, Elizabeth W. Pugh, Peter Chines, Narisu Narisu, Peggy P. White, Tasha E. Fingerlin, Anne U. Jackson, Chun Li, Soumitra Ghosh, Victoria L. Magnuson, Kimberly Colby, Michael R. Erdos, Jason E. Hill, Pablo Hollstein, Kathleen M. Humphreys, Roshni A. Kasad, Jessica Lambert, Konstantinos N. Lazaridis, George Lin, Anabelle Morales-Mena, Kristin Patzkowski, Carrie Pfahl, Rachel Porter, David Rha, Leonid Segal, Yong D. Suh, Jason Tovar, Arun Unni, Christian Welch, Julie A. Douglas, Michael P. Epstein, Elizabeth R. Hauser, William Hagopian, Thomas A. Buchanan, Richard M. Watanabe, Richard N. Bergman, Jaakko Tuomilehto, Francis S. Collins and Michael Boehnke

Diabetes 2004 Mar; 53 (3): 821-829. https://doi.org/10.2337/diabetes.53.3.821

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A Genome-Wide Scan for Type 2 Diabetes in African-American Families Reveals Evidence for a Locus on Chromosome 6q
Michèle M. Sale, Barry I. Freedman, Carl D. Langefeld, Adrienne H. Williams, Pamela J. Hicks, Carla J. Colicigno, Stephanie R. Beck, W. Mark Brown, Stephen S. Rich and Donald W. Bowden

Diabetes 2004 Mar; 53 (3): 830-837. https://doi.org/10.2337/diabetes.53.3.830

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Brief Genetics Report

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A Genome-Wide Search for Type 2 Diabetes Susceptibility Genes in West AfricansThe Africa America Diabetes Mellitus (AADM) Study
Charles N. Rotimi, Guanjie Chen, Adebowale A. Adeyemo, Paulette Furbert-Harris, Debra Guass, Jie Zhou, Kate Berg, Olufemi Adegoke, Albert Amoah, Samuel Owusu, Joseph Acheampong, Kofi Agyenim-Boateng, Benjamin A. Eghan, Johnnie Oli, Godfrey Okafor, Ester Ofoegbu, Babatunde Osotimehin, Fayeofori Abbiyesuku, Thomas Johnson, Theresa Rufus, Olufemi Fasanmade, Rick Kittles, Harold Daniel, Yuanxiu Chen, Georgia Dunston and Francis S. Collins

Diabetes 2004 Mar; 53 (3): 838-841. https://doi.org/10.2337/diabetes.53.3.838

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Genetic Variants in Human Sterol Regulatory Element Binding Protein-1c in Syndromes of Severe Insulin Resistance and Type 2 Diabetes
Matthias Laudes, Inês Barroso, Jian’an Luan, Maria A. Soos, Giles Yeo, Aline Meirhaeghe, Lisa Logie, Antonio Vidal-Puig, Alan J. Schafer, Nick J. Wareham and Stephen O’Rahilly

Diabetes 2004 Mar; 53 (3): 842-846. https://doi.org/10.2337/diabetes.53.3.842

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Genetic Polymorphisms in Peroxisome Proliferator-Activated Receptor δ Associated With Obesity
Hyoung Doo Shin, Byung Lae Park, Lyoung Hyo Kim, Hye Seung Jung, Young Min Cho, Min Kyong Moon, Young Joo Park, Hong Kyu Lee and Kyong Soo Park

Diabetes 2004 Mar; 53 (3): 847-851. https://doi.org/10.2337/diabetes.53.3.847

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Association of Human Endogenous Retrovirus K-18 Polymorphisms With Type 1 Diabetes
Samuel Marguerat, William Y.S. Wang, John A. Todd and Bernard Conrad

Diabetes 2004 Mar; 53 (3): 852-854. https://doi.org/10.2337/diabetes.53.3.852

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Evidence From a Large U.K. Family Collection That Genes Influencing Age of Onset of Type 2 Diabetes Map to Chromosome 12p and to the MODY3/NIDDM2 Locus on 12q24
Steven Wiltshire, Timothy M. Frayling, Christopher J. Groves, Jonathan C. Levy, Graham A. Hitman, Mike Sampson, Mark Walker, Stephan Menzel, Andrew T. Hattersley, Lon R. Cardon and Mark I. McCarthy

Diabetes 2004 Mar; 53 (3): 855-860. https://doi.org/10.2337/diabetes.53.3.855

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Association of the VEGF Gene With Proliferative Diabetic Retinopathy But Not Proteinuria in Diabetes
David Ray, Manoj Mishra, Shirley Ralph, Ian Read, Robert Davies and Paul Brenchley

Diabetes 2004 Mar; 53 (3): 861-864. https://doi.org/10.2337/diabetes.53.3.861

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Scrutiny of the Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1) Locus Reveals Conserved Haplotype Block Structure not Associated With Diabetic Nephropathy
Daniel P.K. Ng, William H. Walker, Kee-Seng Chia, Serena Choo, James H. Warram and Andrzej S. Krolewski

Diabetes 2004 Mar; 53 (3): 865-869. https://doi.org/10.2337/diabetes.53.3.865

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Analysis of the Type 2 Diabetes-Associated Single Nucleotide Polymorphisms in the Genes IRS1, KCNJ11, and PPARG2 in Type 1 Diabetes
Christina Eftychi, Joanna M.M. Howson, Bryan J. Barratt, Adrian Vella, Felicity Payne, Deborah J. Smyth, Rebecca C.J. Twells, Neil M. Walker, Helen E. Rance, Eva Tuomilehto-Wolf, Jaakko Tuomilehto, Dag E. Undlien, Kjersti S. Rønningen, Cristian Guja, Constantin Ionescu-Tı̂irgovişte, David A. Savage and John A. Todd

Diabetes 2004 Mar; 53 (3): 870-873. https://doi.org/10.2337/diabetes.53.3.870

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Erratum

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Erratum
Diabetes 2004 Mar; 53 (3): 874. https://doi.org/10.2337/diabetes.53.3.874

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Table of Contents

Perspectives in Diabetes

Metabolism

Signal Transduction

Obesity Study

Immunology

Islet Study

Pathophysiology

Complication

Genetics

Brief Genetics Report

Erratum

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