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Table of Contents

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June 01 2004; volume 53 issue 6

Rapid Publication

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    Human Pancreatic Duct Cells Exert Tissue Factor-Dependent Procoagulant ActivityRelevance to Islet Transplantation
    Claire Beuneu, Olivier Vosters, Babak Movahedi, Myriam Remmelink, Isabelle Salmon, Daniel Pipeleers, Olivier Pradier, Michel Goldman and Valérie Verhasselt
    Diabetes 2004 Jun; 53 (6): 1407-1411. https://doi.org/10.2337/diabetes.53.6.1407
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Perspective in Diabetes

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    Oxidative Capacity, Lipotoxicity, and Mitochondrial Damage in Type 2 Diabetes
    Patrick Schrauwen and Matthijs K.C. Hesselink
    Diabetes 2004 Jun; 53 (6): 1412-1417. https://doi.org/10.2337/diabetes.53.6.1412
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Metabolism

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    Microvascular Recruitment Is an Early Insulin Effect That Regulates Skeletal Muscle Glucose Uptake In Vivo
    Michelle A. Vincent, Lucy H. Clerk, Jonathan R. Lindner, Alexander L. Klibanov, Michael G. Clark, Stephen Rattigan and Eugene J. Barrett
    Diabetes 2004 Jun; 53 (6): 1418-1423. https://doi.org/10.2337/diabetes.53.6.1418
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    Relationship Between Serum Amyloid A Level and Tanis/SelS mRNA Expression in Skeletal Muscle and Adipose Tissue From Healthy and Type 2 Diabetic Subjects
    Håkan K.R. Karlsson, Hiroki Tsuchida, Staffan Lake, Heikki A. Koistinen and Anna Krook
    Diabetes 2004 Jun; 53 (6): 1424-1428. https://doi.org/10.2337/diabetes.53.6.1424
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Signal Transduction

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    AMP Kinase-Induced Skeletal Muscle Glucose But Not Long-Chain Fatty Acid Uptake Is Dependent on Nitric Oxide
    Jane Shearer, Patrick T. Fueger, Brittney Vorndick, Deanna P. Bracy, Jeffery N. Rottman, Jeffery A. Clanton and David H. Wasserman
    Diabetes 2004 Jun; 53 (6): 1429-1435. https://doi.org/10.2337/diabetes.53.6.1429
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    Effects of Insulin, Contraction, and Phorbol Esters on Mitogen-Activated Protein Kinase Signaling in Skeletal Muscle From Lean and ob/ob Mice
    Ying Leng, Tatiana L. Steiler and Juleen R. Zierath
    Diabetes 2004 Jun; 53 (6): 1436-1444. https://doi.org/10.2337/diabetes.53.6.1436
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    Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1
    Hubert C. Chen, Meghana Rao, Mini P. Sajan, Mary Standaert, Yoshinori Kanoh, Atsushi Miura, Robert V. Farese and Robert V. Farese
    Diabetes 2004 Jun; 53 (6): 1445-1451. https://doi.org/10.2337/diabetes.53.6.1445
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Immunology and Transplantation

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    Advanced Glycation End Products Modulate the Maturation and Function of Peripheral Blood Dendritic Cells
    Claire L. Price, Patrick S. Sharp, Margaret E. North, Sandra J. Rainbow and Stella C. Knight
    Diabetes 2004 Jun; 53 (6): 1452-1458. https://doi.org/10.2337/diabetes.53.6.1452
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    Tracking the Recruitment of Diabetogenic CD8+ T-Cells to the Pancreas in Real Time
    Anna Moore, Jan Grimm, Bingye Han and Pere Santamaria
    Diabetes 2004 Jun; 53 (6): 1459-1466. https://doi.org/10.2337/diabetes.53.6.1459
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Islet Study

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    Changes in the Dimeric State of Neuronal Nitric Oxide Synthase Affect the Kinetics of Secretagogue-Induced Insulin Response
    Anne-Dominique Lajoix, Martine Pugnière, Françoise Roquet, Jean-Claude Mani, Samuel Dietz, Nathalie Linck, Fleur Faurie, Gérard Ribes, Pierre Petit and René Gross
    Diabetes 2004 Jun; 53 (6): 1467-1474. https://doi.org/10.2337/diabetes.53.6.1467
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    The Role of Calcium/Calmodulin-Dependent Protein Kinase Cascade in Glucose Upregulation of Insulin Gene Expression
    Xiao Yu, Koji Murao, Yoshitaka Sayo, Hitomi Imachi, Wen M. Cao, Shouji Ohtsuka, Michio Niimi, Hiroshi Tokumitsu, Hiroyuki Inuzuka, Norman C.W. Wong, Ryoji Kobayashi and Toshihiko Ishida
    Diabetes 2004 Jun; 53 (6): 1475-1481. https://doi.org/10.2337/diabetes.53.6.1475
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    Regulation of α-Cell Function by the β-Cell During Hypoglycemia in Wistar Rats: the “Switch-off” Hypothesis
    Huarong Zhou, Phuong Oanh T. Tran, Shilin Yang, Tao Zhang, Eric LeRoy, Elizabeth Oseid and R. Paul Robertson
    Diabetes 2004 Jun; 53 (6): 1482-1487. https://doi.org/10.2337/diabetes.53.6.1482
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    Regulation of α-Cell Function by the β-Cell in Isolated Human and Rat Islets Deprived of Glucose: the “Switch-off” Hypothesis
    Kristine M. Hope, Phuong Oanh T. Tran, Huarong Zhou, Elizabeth Oseid, Eric Leroy and R. Paul Robertson
    Diabetes 2004 Jun; 53 (6): 1488-1495. https://doi.org/10.2337/diabetes.53.6.1488
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    Glucose and Insulin Treatment of Insulinoma Cells Results in Transcriptional Regulation of a Common Set of Genes
    Mitsuru Ohsugi, Corentin Cras-Méneur, Yiyong Zhou, Wesley Warren, Ernesto Bernal-Mizrachi and M. Alan Permutt
    Diabetes 2004 Jun; 53 (6): 1496-1508. https://doi.org/10.2337/diabetes.53.6.1496
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    Diabetes Due to a Progressive Defect in β-Cell Mass in Rats Transgenic for Human Islet Amyloid Polypeptide (HIP Rat)A New Model for Type 2 Diabetes
    Alexandra E. Butler, Jennifer Jang, Tatyana Gurlo, Maynard D. Carty, Walter C. Soeller and Peter C. Butler
    Diabetes 2004 Jun; 53 (6): 1509-1516. https://doi.org/10.2337/diabetes.53.6.1509
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    Islet Secretory Defect in Insulin Receptor Substrate 1 Null Mice Is Linked With Reduced Calcium Signaling and Expression of Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA)-2b and -3
    Rohit N. Kulkarni, Michael G. Roper, Gabriella Dahlgren, David Q. Shih, Lisa M. Kauri, Jennifer L. Peters, Markus Stoffel and Robert T. Kennedy
    Diabetes 2004 Jun; 53 (6): 1517-1525. https://doi.org/10.2337/diabetes.53.6.1517
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    Regulation of Rat Pancreatic CCKB Receptor and Somatostatin Expression by Insulin
    Sophie Julien, Jean Laine and Jean Morisset
    Diabetes 2004 Jun; 53 (6): 1526-1534. https://doi.org/10.2337/diabetes.53.6.1526
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Pathophysiology

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    Influence of Autonomic Neuropathy on QTc Interval Lengthening During Hypoglycemia in Type 1 Diabetes
    Stuart P. Lee, Lishan Yeoh, Nigel D. Harris, Catherine M. Davies, Robert T. Robinson, Andrew Leathard, Christopher Newman, Ian A. Macdonald and Simon R. Heller
    Diabetes 2004 Jun; 53 (6): 1535-1542. https://doi.org/10.2337/diabetes.53.6.1535
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    Muscle Strength in Type 2 Diabetes
    Henning Andersen, Søren Nielsen, Carl E. Mogensen and Johannes Jakobsen
    Diabetes 2004 Jun; 53 (6): 1543-1548. https://doi.org/10.2337/diabetes.53.6.1543
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    Differences in Insulin Resistance in Nondiabetic Subjects With Isolated Impaired Glucose Tolerance or Isolated Impaired Fasting Glucose
    Andreas Festa, Ralph D’Agostino, Anthony J.G. Hanley, Andrew J. Karter, Mohammed F. Saad and Steven M. Haffner
    Diabetes 2004 Jun; 53 (6): 1549-1555. https://doi.org/10.2337/diabetes.53.6.1549
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Complication

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    Molecular Alterations Underlie Nodal and Paranodal Degeneration in Type 1 Diabetic Neuropathy and Are Prevented by C-Peptide
    Anders A.F. Sima, Weixian Zhang, Zhen-Guo Li, Yuichi Murakawa and Christopher R. Pierson
    Diabetes 2004 Jun; 53 (6): 1556-1563. https://doi.org/10.2337/diabetes.53.6.1556
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    Early Endothelial Dysfunction Severely Impairs Skin Blood Flow Response to Local Pressure Application in Streptozotocin-Induced Diabetic Mice
    Dominique Sigaudo-Roussel, Claire Demiot, Bérengère Fromy, Audrey Koïtka, Georges Lefthériotis, Pierre Abraham and Jean Louis Saumet
    Diabetes 2004 Jun; 53 (6): 1564-1569. https://doi.org/10.2337/diabetes.53.6.1564
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    Association Between Mannose-Binding Lectin and Vascular Complications in Type 1 Diabetes
    Troels K. Hansen, Lise Tarnow, Steffen Thiel, Rudi Steffensen, Coen D. Stehouwer, Casper G. Schalkwijk, Hans-Henrik Parving and Allan Flyvbjerg
    Diabetes 2004 Jun; 53 (6): 1570-1576. https://doi.org/10.2337/diabetes.53.6.1570
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Genetics

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    A New Mouse Model of Type 2 Diabetes, Produced by N-Ethyl-Nitrosourea Mutagenesis, Is the Result of a Missense Mutation in the Glucokinase Gene
    Ayo A. Toye, Lee Moir, Alison Hugill, Liz Bentley, Julie Quarterman, Vesna Mijat, Tertius Hough, Michelle Goldsworthy, Alison Haynes, A. Jacqueline Hunter, Mick Browne, Nigel Spurr and Roger D. Cox
    Diabetes 2004 Jun; 53 (6): 1577-1583. https://doi.org/10.2337/diabetes.53.6.1577
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    Interaction and Association Analysis of a Type 1 Diabetes Susceptibility Locus on Chromosome 5q11-q13 and the 7q32 Chromosomal Region in Scandinavian Families
    Pernilla Holm, Berit Rydlander, Holger Luthman and Ingrid Kockum
    Diabetes 2004 Jun; 53 (6): 1584-1591. https://doi.org/10.2337/diabetes.53.6.1584
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    A Novel Syndrome of Autosomal-Dominant Hyperinsulinemic Hypoglycemia Linked to a Mutation in the Human Insulin Receptor Gene
    Kurt Højlund, Torben Hansen, Maria Lajer, Jan Erik Henriksen, Klaus Levin, Jörgen Lindholm, Oluf Pedersen and Henning Beck-Nielsen
    Diabetes 2004 Jun; 53 (6): 1592-1598. https://doi.org/10.2337/diabetes.53.6.1592
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Brief Genetics Report

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    Diabetes-Associated Mutations in Insulin Identify Invariant Receptor Contacts
    Bin Xu, Shi-Quan Hu, Ying-Chi Chu, Shuhua Wang, Run-ying Wang, Satoe H. Nakagawa, Panayotis G. Katsoyannis and Michael A. Weiss
    Diabetes 2004 Jun; 53 (6): 1599-1602. https://doi.org/10.2337/diabetes.53.6.1599
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    Leptin and Leptin Receptor Gene Polymorphisms and Changes in Glucose Homeostasis in Response to Regular Exercise in Nondiabetic IndividualsThe HERITAGE Family Study
    Timo A. Lakka, Tuomo Rankinen, S. John Weisnagel, Yvon C. Chagnon, Hanna-Maaria Lakka, Olavi Ukkola, Normand Boulé, Treva Rice, Arthur S. Leon, James S. Skinner, Jack H. Wilmore, D.C. Rao, Richard Bergman and Claude Bouchard
    Diabetes 2004 Jun; 53 (6): 1603-1608. https://doi.org/10.2337/diabetes.53.6.1603
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    Genome-wide Scan for Type 2 Diabetes Loci in Hong Kong Chinese and Confirmation of a Susceptibility Locus on Chromosome 1q21-q25
    Maggie C.Y. Ng, Wing-Yee So, Nancy J. Cox, Vincent K.L. Lam, Clive S. Cockram, Julian A.J.H. Critchley, Graeme I. Bell and Juliana C.N. Chan
    Diabetes 2004 Jun; 53 (6): 1609-1613. https://doi.org/10.2337/diabetes.53.6.1609
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Pharmacology and Therapeutics

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    Lower Within-Subject Variability of Insulin Detemir in Comparison to NPH Insulin and Insulin Glargine in People With Type 1 Diabetes
    Tim Heise, Leszek Nosek, Birgitte Biilmann Rønn, Lars Endahl, Lutz Heinemann, Christoph Kapitza and Eberhard Draeger
    Diabetes 2004 Jun; 53 (6): 1614-1620. https://doi.org/10.2337/diabetes.53.6.1614
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    Mechanisms of Early Insulin-Sensitizing Effects of Thiazolidinediones in Type 2 Diabetes
    Julia Tonelli, Weijie Li, Preeti Kishore, Utpal B. Pajvani, Elize Kwon, Charles Weaver, Philipp E. Scherer and Meredith Hawkins
    Diabetes 2004 Jun; 53 (6): 1621-1629. https://doi.org/10.2337/diabetes.53.6.1621
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In this Issue

June 2004, 53(6)
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  • Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis
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  • The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion
  • A Polymorphism in the Glucocorticoid Receptor Gene, Which Decreases Sensitivity to Glucocorticoids In Vivo, Is Associated With Low Insulin and Cholesterol Levels
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