Diabetes: 53 (8)

August 01 2004; volume 53 issue 8

Rapid Publication

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Abnormal Glucose Homeostasis due to Chronic Hyperresistinemia
Shamina M. Rangwala, A. Sophie Rich, Ben Rhoades, Jennifer S. Shapiro, Silvana Obici, Luciano Rossetti and Mitchell A. Lazar

Diabetes 2004 Aug; 53 (8): 1937-1941. https://doi.org/10.2337/diabetes.53.8.1937

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Perspectives in Diabetes

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Does the Glucose-Dependent Insulin Secretion Mechanism Itself Cause Oxidative Stress in Pancreatic β-Cells?
Leonid E. Fridlyand and Louis H. Philipson

Diabetes 2004 Aug; 53 (8): 1942-1948. https://doi.org/10.2337/diabetes.53.8.1942

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Signal Transduction

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PYY_3–36 Reinforces Insulin Action on Glucose Disposal in Mice Fed a High-Fat Diet
Anita M. van den Hoek, Annemieke C. Heijboer, Eleonora P.M. Corssmit, Peter J. Voshol, Johannes A. Romijn, Louis M. Havekes and Hanno Pijl

Diabetes 2004 Aug; 53 (8): 1949-1952. https://doi.org/10.2337/diabetes.53.8.1949

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Potential Role for AMP-Activated Protein Kinase in Hypoglycemia Sensing in the Ventromedial Hypothalamus
Rory J. McCrimmon, Xiaoning Fan, Yuyan Ding, Wanling Zhu, Ralph J. Jacob and Robert S. Sherwin

Diabetes 2004 Aug; 53 (8): 1953-1958. https://doi.org/10.2337/diabetes.53.8.1953

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Obesity Studies

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The Regulation of Glucose-Excited Neurons in the Hypothalamic Arcuate Nucleus by Glucose and Feeding-Relevant Peptides
R. Wang, X. Liu, S.T. Hentges, A.A. Dunn-Meynell, B.E. Levin, W. Wang and V.H. Routh

Diabetes 2004 Aug; 53 (8): 1959-1965. https://doi.org/10.2337/diabetes.53.8.1959

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Effects of Different Hypocaloric Diets on Protein Secretion From Adipose Tissue of Obese Women
Elisabet Arvidsson, Nathalie Viguerie, Ingalena Andersson, Camilla Verdich, Dominique Langin and Peter Arner

Diabetes 2004 Aug; 53 (8): 1966-1971. https://doi.org/10.2337/diabetes.53.8.1966

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Immunology and Transplantation

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Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice Is Controlled by Allelic Variants of Idd3
Todd Pearson, Peter Weiser, Thomas G. Markees, David V. Serreze, Linda S. Wicker, Laurence B. Peterson, Anne-Marie Cumisky, Leonard D. Shultz, John P. Mordes, Aldo A. Rossini and Dale L. Greiner

Diabetes 2004 Aug; 53 (8): 1972-1978. https://doi.org/10.2337/diabetes.53.8.1972

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Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin
Gerben Bouma, Wai Kwan Lam-Tse, Annet F. Wierenga-Wolf, Hemmo A. Drexhage and Marjan A. Versnel

Diabetes 2004 Aug; 53 (8): 1979-1986. https://doi.org/10.2337/diabetes.53.8.1979

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GAD65-Specific CD4⁺ T-Cells with High Antigen Avidity Are Prevalent in Peripheral Blood of Patients With Type 1 Diabetes
Helena Reijonen, Roberto Mallone, Anne-Kristin Heninger, Elsa M. Laughlin, Sharon A. Kochik, Ben Falk, William W. Kwok, Carla Greenbaum and Gerald T. Nepom

Diabetes 2004 Aug; 53 (8): 1987-1994. https://doi.org/10.2337/diabetes.53.8.1987

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Flt3-Ligand Treatment Prevents Diabetes in NOD Mice
Paula M. Chilton, Francine Rezzoug, Isabelle Fugier-Vivier, Leslie A. Weeter, Hong Xu, Yiming Huang, Mukunda B. Ray and Suzanne T. Ildstad

Diabetes 2004 Aug; 53 (8): 1995-2002. https://doi.org/10.2337/diabetes.53.8.1995

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Hyperresponsiveness, Resistance to B-Cell Receptor—Dependent Activation-Induced Cell Death, and Accumulation of Hyperactivated B-Cells in Islets Is Associated With the Onset of Insulitis but not Type 1 Diabetes
Shabbir Hussain, Konstantin V. Salojin and Terry L. Delovitch

Diabetes 2004 Aug; 53 (8): 2003-2011. https://doi.org/10.2337/diabetes.53.8.2003

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Major Histocompatibility Complex Class I Shedding and Programmed Cell Death Stimulated Through the Proinflammatory P2X₇ ReceptorA Candidate Susceptibility Gene for NOD Diabetes
James I. Elliott and Christopher F. Higgins

Diabetes 2004 Aug; 53 (8): 2012-2017. https://doi.org/10.2337/diabetes.53.8.2012

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Islet Studies

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Autocrine Regulation of Single Pancreatic β-Cell Survival
Víctor Navarro-Tableros, M. Carmen Sánchez-Soto, Santiago García and Marcia Hiriart

Diabetes 2004 Aug; 53 (8): 2018-2023. https://doi.org/10.2337/diabetes.53.8.2018

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Inhibition of Activin Signaling Induces Pancreatic Epithelial Cell Expansion and Diminishes Terminal Differentiation of Pancreatic β-Cells
You-Qing Zhang, Mary Malo Cleary, Yingjie Si, Guoxun Liu, Yuzuru Eto, Marcie Kritzik, Sandrine Dabernat, Ayse G. Kayali and Nora Sarvetnick

Diabetes 2004 Aug; 53 (8): 2024-2033. https://doi.org/10.2337/diabetes.53.8.2024

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Extracellular Matrix Protects Pancreatic β-Cells Against ApoptosisRole of Short- and Long-Term Signaling Pathways
Eva Hammar, Géraldine Parnaud, Domenico Bosco, Nadja Perriraz, Kathrin Maedler, Marc Donath, Dominique G. Rouiller and Philippe A. Halban

Diabetes 2004 Aug; 53 (8): 2034-2041. https://doi.org/10.2337/diabetes.53.8.2034

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Prospective Isolation of Multipotent Pancreatic Progenitors Using Flow-Cytometric Cell Sorting
Atsushi Suzuki, Hiromitsu Nakauchi and Hideki Taniguchi

Diabetes 2004 Aug; 53 (8): 2143-2152. https://doi.org/10.2337/diabetes.53.8.2143

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Pathophysiology

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Insulin Dose-Response Curves for Stimulation of Splanchnic Glucose Uptake and Suppression of Endogenous Glucose Production Differ in Nondiabetic Humans and Are Abnormal in People With Type 2 Diabetes
Rita Basu, Ananda Basu, C. Michael Johnson, W. Frederick Schwenk and Robert A. Rizza

Diabetes 2004 Aug; 53 (8): 2042-2050. https://doi.org/10.2337/diabetes.53.8.2042

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Splanchnic Cortisol Production Occurs in HumansEvidence for Conversion of Cortisone to Cortisol Via the 11-β Hydroxysteroid Dehydrogenase (11β-HSD) Type 1 Pathway
Rita Basu, Ravinder J. Singh, Ananda Basu, Elizabeth G. Chittilapilly, C. Michael Johnson, Gianna Toffolo, Claudio Cobelli and Robert A. Rizza

Diabetes 2004 Aug; 53 (8): 2051-2059. https://doi.org/10.2337/diabetes.53.8.2051

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Interactions Between Endothelin and Nitric Oxide in the Regulation of Vascular Tone in Obesity and Diabetes
Kieren J. Mather, Amale Lteif, Helmut O. Steinberg and Alain D. Baron

Diabetes 2004 Aug; 53 (8): 2060-2066. https://doi.org/10.2337/diabetes.53.8.2060

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Partial Gene Deletion of Endothelial Nitric Oxide Synthase Predisposes to Exaggerated High-Fat Diet—Induced Insulin Resistance and Arterial Hypertension
Stéphane Cook, Olivier Hugli, Marc Egli, Barbara Ménard, Sébastien Thalmann, Claudio Sartori, Christophe Perrin, Pascal Nicod, Bernard Thorens, Peter Vollenweider, Urs Scherrer and Rémy Burcelin

Diabetes 2004 Aug; 53 (8): 2067-2072. https://doi.org/10.2337/diabetes.53.8.2067

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Vasomotor Responses to Hypoxia in Type 2 Diabetes
Cara J. Weisbrod, Peter R. Eastwood, Gerard O’Driscoll, Jennifer H. Walsh, Matthew Best, John R. Halliwill and Daniel J. Green

Diabetes 2004 Aug; 53 (8): 2073-2078. https://doi.org/10.2337/diabetes.53.8.2073

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Proinflammatory Cytokines, Markers of Cardiovascular Risks, Oxidative Stress, and Lipid Peroxidation in Patients With Hyperglycemic Crises
Frankie B. Stentz, Guillermo E. Umpierrez, Ruben Cuervo and Abbas E. Kitabchi

Diabetes 2004 Aug; 53 (8): 2079-2086. https://doi.org/10.2337/diabetes.53.8.2079

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Intra-Abdominal Fat Is a Major Determinant of the National Cholesterol Education Program Adult Treatment Panel III Criteria for the Metabolic Syndrome
Darcy B. Carr, Kristina M. Utzschneider, Rebecca L. Hull, Keiichi Kodama, Barbara M. Retzlaff, John D. Brunzell, Jane B. Shofer, Brian E. Fish, Robert H. Knopp and Steven E. Kahn

Diabetes 2004 Aug; 53 (8): 2087-2094. https://doi.org/10.2337/diabetes.53.8.2087

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Impaired Glucose Tolerance, but not Impaired Fasting Glucose, Is Associated With Increased Levels of Coronary Heart Disease Risk FactorsResults From the Baltimore Longitudinal Study on Aging
Deirdre R. Blake, James B. Meigs, Denis C. Muller, Samer S. Najjar, Reubin Andres and David M. Nathan

Diabetes 2004 Aug; 53 (8): 2095-2100. https://doi.org/10.2337/diabetes.53.8.2095

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Complication

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Diminished Loss of Proteoglycans and Lack of Albuminuria in Protein Kinase C-α—Deficient Diabetic Mice
Jan Menne, Joon-Keun Park, Martin Boehne, Marlies Elger, Carsten Lindschau, Torsten Kirsch, Matthias Meier, Faikah Gueler, Annette Fiebeler, Ferdinand H. Bahlmann, Michael Leitges and Hermann Haller

Diabetes 2004 Aug; 53 (8): 2101-2109. https://doi.org/10.2337/diabetes.53.8.2101

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Oxidative Stress Affects Synaptosomal γ-Aminobutyric Acid and Glutamate Transport in Diabetic RatsThe Role of Insulin
Ana I. Duarte, Maria S. Santos, Raquel Seiça and Catarina R. Oliveira

Diabetes 2004 Aug; 53 (8): 2110-2116. https://doi.org/10.2337/diabetes.53.8.2110

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Surface Expression of Collagen Receptor Fc Receptor-γ/Glycoprotein VI Is Enhanced on Platelets in Type 2 Diabetes and Mediates Release of CD40 Ligand and Activation of Endothelial Cells
Natalia Cabeza, Zhongyan Li, Christian Schulz, Elisabeth Kremmer, Steffen Massberg, Andreas Bültmann and Meinrad Gawaz

Diabetes 2004 Aug; 53 (8): 2117-2121. https://doi.org/10.2337/diabetes.53.8.2117

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Brief Genetics Report

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Polymorphic Variations in the Neurogenic Differentiation-1, Neurogenin-3, and Hepatocyte Nuclear Factor-1α Genes Contribute to Glucose Intolerance in a South Indian Population
Alan E. Jackson, Paul G. Cassell, Bernard V. North, Shanti Vijayaraghavan, Susan V. Gelding, Ambady Ramachandran, Chamukuttan Snehalatha and Graham A. Hitman

Diabetes 2004 Aug; 53 (8): 2122-2125. https://doi.org/10.2337/diabetes.53.8.2122

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Variation at the Insulin Gene VNTR (Variable Number Tandem Repeat) Polymorphism and Early GrowthStudies in a Large Finnish Birth Cohort
Amanda J. Bennett, Ulla Sovio, Aimo Ruokonen, Hannu Martikainen, Anneli Pouta, Saara Taponen, Anna-Liisa Hartikainen, Vanessa J. King, Paul Elliott, Marjo-Riitta Järvelin and Mark I. McCarthy

Diabetes 2004 Aug; 53 (8): 2126-2131. https://doi.org/10.2337/diabetes.53.8.2126

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Adiponectin Receptor 1 Gene (ADIPOR1) as a Candidate for Type 2 Diabetes and Insulin Resistance
Hua Wang, Hailing Zhang, Yiwen Jia, Zhengxian Zhang, Rebekah Craig, Xiaoqin Wang and Steven C. Elbein

Diabetes 2004 Aug; 53 (8): 2132-2136. https://doi.org/10.2337/diabetes.53.8.2132

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Quantitative Trait Loci Near the Insulin-Degrading Enzyme (IDE) Gene Contribute to Variation in Plasma Insulin Levels
Harvest F. Gu, Suad Efendic, Sofia Nordman, Claes-Göran Östenson, Kerstin Brismar, Anthony J. Brookes and Jonathan A. Prince

Diabetes 2004 Aug; 53 (8): 2137-2142. https://doi.org/10.2337/diabetes.53.8.2137

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SREBF-1 Gene Polymorphisms Are Associated With Obesity and Type 2 Diabetes in French Obese and Diabetic Cohorts
Delphine Eberlé, Karine Clément, David Meyre, Mourad Sahbatou, Martine Vaxillaire, Annie Le Gall, Pascal Ferré, Arnaud Basdevant, Philippe Froguel and Fabienne Foufelle

Diabetes 2004 Aug; 53 (8): 2153-2157. https://doi.org/10.2337/diabetes.53.8.2153

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DPB1 Alleles Are Associated With Type 1 Diabetes Susceptibility in Multiple Ethnic Groups
Thomas D. Cruz, Ana M. Valdes, Alma Santiago, Teresa Frazer de Llado, Leslie J. Raffel, Adina Zeidler, Jerome I. Rotter, Henry A. Erlich, Marian Rewers, Teodorica Bugawan and Janelle A. Noble

Diabetes 2004 Aug; 53 (8): 2158-2163. https://doi.org/10.2337/diabetes.53.8.2158

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Severe Persistent Hyperinsulinemic Hypoglycemia due to a De Novo Glucokinase Mutation
Antonio L. Cuesta-Muñoz, Hanna Huopio, Timo Otonkoski, Juan M. Gomez-Zumaquero, Kirsti Näntö-Salonen, Jacques Rahier, Soledad López-Enriquez, Maria A. García-Gimeno, Pascual Sanz, Federico C. Soriguer and Markku Laakso

Diabetes 2004 Aug; 53 (8): 2164-2168. https://doi.org/10.2337/diabetes.53.8.2164

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Pharmacology & Therapeutics

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Effects of Rosiglitazone and Metformin on Liver Fat Content, Hepatic Insulin Resistance, Insulin Clearance, and Gene Expression in Adipose Tissue in Patients With Type 2 Diabetes
Mirja Tiikkainen, Anna-Maija Häkkinen, Elena Korsheninnikova, Tuulikki Nyman, Sari Mäkimattila and Hannele Yki-Järvinen

Diabetes 2004 Aug; 53 (8): 2169-2176. https://doi.org/10.2337/diabetes.53.8.2169

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Errata

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Errata
Diabetes 2004 Aug; 53 (8): 2177. https://doi.org/10.2337/diabetes.53.8.2177

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Errata
Diabetes 2004 Aug; 53 (8): 2177. https://doi.org/10.2337/diabetes.53.8.2177-a

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Table of Contents

Rapid Publication

Perspectives in Diabetes

Signal Transduction

Obesity Studies

Immunology and Transplantation

Islet Studies

Pathophysiology

Complication

Brief Genetics Report

Pharmacology & Therapeutics

Errata

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