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Genetics

Type 1 Diabetes

Evidence for Susceptibility Loci from Four Genome-Wide Linkage Scans in 1,435 Multiplex Families

  1. Patrick Concannon1,
  2. Henry A. Erlich2,
  3. Cecile Julier3,
  4. Grant Morahan4,
  5. Jørn Nerup5,
  6. Flemming Pociot5,
  7. John A. Todd6,
  8. Stephen S. Rich7 and
  9. the Type 1 Diabetes Genetics Consortium*
  1. 1Benaroya Research Institute, Seattle, Washington
  2. 2Roche Molecular Systems, Alameda, California
  3. 3Pasteur Institute, Paris, France
  4. 4The Western Australian Institute of Medical Research, Perth, Australia
  5. 5Steno Diabetes Center, Gentofte, Denmark
  6. 6Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes Inflammation Laboratory, Cambridge University, Cambridge, U.K
  7. 7Wake Forest University School of Medicine, Winston-Salem, North Carolina
  1. Address correspondence and reprint requests to Stephen S. Rich, PhD, Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157. E-mail: srich{at}wfubmc.edu
Diabetes 2005 Oct; 54(10): 2995-3001. https://doi.org/10.2337/diabetes.54.10.2995
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Data supplements

  • Data Supplement

    Files in this Data Supplement:

    • Linkage Analysis for Chromosome 1
    • Linkage Analysis for Chromosome 10
    • Linkage Analysis for Chromosome 11
    • Linkage Analysis for Chromosome 12
    • Linkage Analysis for Chromosome 13
    • Linkage Analysis for Chromosome 14
    • Linkage Analysis for Chromosome 15
    • Linkage Analysis for Chromosome 16
    • Linkage Analysis for Chromosome 17
    • Linkage Analysis for Chromosome 18
    • Linkage Analysis for Chromosome 19
    • Linkage Analysis for Chromosome 2
    • Linkage Analysis for Chromosome 20
    • Linkage Analysis for Chromosome 21
    • Linkage Analysis for Chromosome 22
    • Linkage Analysis for Chromosome 23
    • Linkage Analysis for Chromosome 3
    • Linkage Analysis for Chromosome 4
    • Linkage Analysis for Chromosome 5
    • Linkage Analysis for Chromosome 6
    • Linkage Analysis for Chromosome 7
    • Linkage Analysis for Chromosome 8
    • Linkage Analysis for Chromosome 9
    • Legend for Appendix Figures
    • Appendix Table: Composition and characteristics of families in the linkage scan.
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October 2005, 54(10)
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Type 1 Diabetes
Patrick Concannon, Henry A. Erlich, Cecile Julier, Grant Morahan, Jørn Nerup, Flemming Pociot, John A. Todd, Stephen S. Rich, the Type 1 Diabetes Genetics Consortium*
Diabetes Oct 2005, 54 (10) 2995-3001; DOI: 10.2337/diabetes.54.10.2995

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Type 1 Diabetes
Patrick Concannon, Henry A. Erlich, Cecile Julier, Grant Morahan, Jørn Nerup, Flemming Pociot, John A. Todd, Stephen S. Rich, the Type 1 Diabetes Genetics Consortium*
Diabetes Oct 2005, 54 (10) 2995-3001; DOI: 10.2337/diabetes.54.10.2995
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  • Single Insulin-Specific CD8+ T Cells Show Characteristic Gene Expression Profiles in Human Type 1 Diabetes
  • Cesarean Section and Interferon-Induced Helicase Gene Polymorphisms Combine to Increase Childhood Type 1 Diabetes Risk
  • PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim
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