Evidence that the Mitochondrial Leucyl tRNA Synthetase (LARS2) Gene Represents a Novel Type 2 Diabetes Susceptibility Gene

Leen M. ‘t Hart; Torben Hansen; Ingrid Rietveld; Jacqueline M. Dekker; Giel Nijpels; George M.C. Janssen; Pascal A. Arp; André G. Uitterlinden; Torben Jørgensen; Knut Borch-Johnsen; Huibert A.P. Pols; Oluf Pedersen; Cornelia M. van Duijn; Robert J. Heine; J. Antonie Maassen

doi:10.2337/diabetes.54.6.1892

Brief Genetics Reports

Evidence that the Mitochondrial Leucyl tRNA Synthetase (LARS2) Gene Represents a Novel Type 2 Diabetes Susceptibility Gene

Leen M. ‘t Hart1,
Torben Hansen2,
Ingrid Rietveld3,
Jacqueline M. Dekker4,
Giel Nijpels4,
George M.C. Janssen1,
Pascal A. Arp5,
André G. Uitterlinden5,
Torben Jørgensen6,
Knut Borch-Johnsen2 7,
Huibert A.P. Pols5,
Oluf Pedersen2 7,
Cornelia M. van Duijn3,
Robert J. Heine4 and
J. Antonie Maassen1 4

¹Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands
²Steno Diabetes Center and Hagedorn Research Institute, Gentofte, Denmark
³Department of Genetic Epidemiology and Biostatistics, Erasmus University Medical Center, Rotterdam, the Netherlands
⁴Institute for Research in Extramural Medicine, Free University Medical Center, Amsterdam, the Netherlands
⁵Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands
⁶Research Center for Prevention and Health, Copenhagen County, Glostrup University Hospital, Glostrup, Denmark
⁷Faculty of Health Science, Aarhus University, Aarhus, Denmark

Address correspondence and reprint requests to L.M. ‘t Hart, PhD, Leiden University Medical Center, Department of Molecular Cell Biology, Wassenaarseweg 72, 2333 AL Leiden, Netherlands. E-mail: l.m.t_hart{at}lumc.nl

Diabetes 2005 Jun; 54(6): 1892-1895. https://doi.org/10.2337/diabetes.54.6.1892

Article Information

vol. 54 no. 6 1892-1895

DOI

https://doi.org/10.2337/diabetes.54.6.1892

PubMed

15919814

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

March 21, 2005
November 25, 2004
Published in print May 25, 2005.

DIABETES

Author Information

Leen M. ‘t Hart1,
Torben Hansen2,
Ingrid Rietveld3,
Jacqueline M. Dekker4,
Giel Nijpels4,
George M.C. Janssen1,
Pascal A. Arp5,
André G. Uitterlinden5,
Torben Jørgensen6,
Knut Borch-Johnsen2 7,
Huibert A.P. Pols5,
Oluf Pedersen2 7,
Cornelia M. van Duijn3,
Robert J. Heine4 and
J. Antonie Maassen1 4

¹Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands
²Steno Diabetes Center and Hagedorn Research Institute, Gentofte, Denmark
³Department of Genetic Epidemiology and Biostatistics, Erasmus University Medical Center, Rotterdam, the Netherlands
⁴Institute for Research in Extramural Medicine, Free University Medical Center, Amsterdam, the Netherlands
⁵Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands
⁶Research Center for Prevention and Health, Copenhagen County, Glostrup University Hospital, Glostrup, Denmark
⁷Faculty of Health Science, Aarhus University, Aarhus, Denmark

Address correspondence and reprint requests to L.M. ‘t Hart, PhD, Leiden University Medical Center, Department of Molecular Cell Biology, Wassenaarseweg 72, 2333 AL Leiden, Netherlands. E-mail: l.m.t_hart{at}lumc.nl

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