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Islet Studies

Pancreatic β-Cells Secrete Insulin in Fast- and Slow-Release Forms

  1. Darren J. Michael1,
  2. Robert A. Ritzel2,
  3. Leena Haataja3 and
  4. Robert H. Chow1
  1. 1Department of Physiology and Biophysics, Keck School of Medicine, Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California
  2. 2Department of Endocrinology, University of Heidelberg, Heidelberg, Germany
  3. 3Department of Endocrinology, Larry Hillblom Islet Research Center, University of California, Los Angeles, California
  1. Address correspondence and reprint requests to Robert H. Chow, University of Southern California, Department of Physiology and Biophysics, 1501 San Pablo St., ZNI 323, Los Angeles, CA 90089. E-mail: rchow{at}usc.edu
Diabetes 2006 Mar; 55(3): 600-607. https://doi.org/10.2337/diabetes.55.03.06.db05-1054
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Article Information

vol. 55 no. 3 600-607
DOI 
https://doi.org/10.2337/diabetes.55.03.06.db05-1054
PubMed 
16505221

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • December 15, 2005
  • August 16, 2005
  • Published in print February 27, 2006.

Copyright & Usage 
DIABETES

Author Information

  1. Darren J. Michael1,
  2. Robert A. Ritzel2,
  3. Leena Haataja3 and
  4. Robert H. Chow1
  1. 1Department of Physiology and Biophysics, Keck School of Medicine, Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California
  2. 2Department of Endocrinology, University of Heidelberg, Heidelberg, Germany
  3. 3Department of Endocrinology, Larry Hillblom Islet Research Center, University of California, Los Angeles, California
  1. Address correspondence and reprint requests to Robert H. Chow, University of Southern California, Department of Physiology and Biophysics, 1501 San Pablo St., ZNI 323, Los Angeles, CA 90089. E-mail: rchow{at}usc.edu
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Pancreatic β-Cells Secrete Insulin in Fast- and Slow-Release Forms
Darren J. Michael, Robert A. Ritzel, Leena Haataja, Robert H. Chow
Diabetes Mar 2006, 55 (3) 600-607; DOI: 10.2337/diabetes.55.03.06.db05-1054

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Pancreatic β-Cells Secrete Insulin in Fast- and Slow-Release Forms
Darren J. Michael, Robert A. Ritzel, Leena Haataja, Robert H. Chow
Diabetes Mar 2006, 55 (3) 600-607; DOI: 10.2337/diabetes.55.03.06.db05-1054
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  • Loss of Furin in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction
  • SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients
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