Diabetes: 56 (2)

February 01 2007; volume 56 issue 2

Obesity Studies

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IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance
Stephen B. Wheatcroft, Mark T. Kearney, Ajay M. Shah, Vivienne A. Ezzat, John R. Miell, Michael Modo, Stephen C.R. Williams, Will P. Cawthorn, Gema Medina-Gomez, Antonio Vidal-Puig, Jaswinder K. Sethi and Paul A. Crossey

Diabetes 2007 Feb; 56 (2): 285-294. https://doi.org/10.2337/db06-0436

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Wnt10b Inhibits Obesity in ob/ob and Agouti Mice
Wendy S. Wright, Kenneth A. Longo, Vernon W. Dolinsky, Isabelle Gerin, Sona Kang, Christina N. Bennett, Shian-Huey Chiang, Tyler C. Prestwich, Catherine Gress, Charles F. Burant, Vedrana S. Susulic and Ormond A. MacDougald

Diabetes 2007 Feb; 56 (2): 295-303. https://doi.org/10.2337/db06-1339

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Islet Studies

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Identification of the Amyloid-Degrading Enzyme Neprilysin in Mouse Islets and Potential Role in Islet Amyloidogenesis
Sakeneh Zraika, Rebecca L. Hull, Jayalakshmi Udayasankar, Anne Clark, Kristina M. Utzschneider, Jenny Tong, Fernando Gerchman and Steven E. Kahn

Diabetes 2007 Feb; 56 (2): 304-310. https://doi.org/10.2337/db06-0430

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Melanin Concentrating Hormone Is a Novel Regulator of Islet Function and Growth
Pavlos Pissios, Umut Ozcan, Efi Kokkotou, Terumasa Okada, Chong Wee Liew, Siming Liu, Jennifer N. Peters, Gabriella Dahlgren, Jason Karamchandani, Yogish C. Kudva, Amarnath J. Kurpad, Robert T. Kennedy, Eleftheria Maratos-Flier and Rohit N. Kulkarni

Diabetes 2007 Feb; 56 (2): 311-319. https://doi.org/10.2337/db06-0708

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Glucose-Dependent Regulation of γ-Aminobutyric Acid (GABA_A) Receptor Expression in Mouse Pancreatic Islet α-Cells
Sarah J. Bailey, Magalie A. Ravier and Guy A. Rutter

Diabetes 2007 Feb; 56 (2): 320-327. https://doi.org/10.2337/db06-0712

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An ATP-Binding Mutation (G334D) in KCNJ11 Is Associated With a Sulfonylurea-Insensitive Form of Developmental Delay, Epilepsy, and Neonatal Diabetes
Ricard Masia, Joseph C. Koster, Stefano Tumini, Francesco Chiarelli, Carlo Colombo, Colin G. Nichols and Fabrizio Barbetti

Diabetes 2007 Feb; 56 (2): 328-336. https://doi.org/10.2337/db06-1275

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Glucotoxicity in the INS-1 Rat Insulinoma Cell Line Is Mediated by the Orphan Nuclear Receptor Small Heterodimer Partner
Keun-Gyu Park, Kyeong-Min Lee, Hye-Young Seo, Ji-Ho Suh, Hye-Soon Kim, Li Wang, Kyu-Chang Won, Hyoung-Woo Lee, Joong-Yeol Park, Ki-Up Lee, Jung-Guk Kim, Bo-Wan Kim, Hueng-Sik Choi and In-Kyu Lee

Diabetes 2007 Feb; 56 (2): 431-437. https://doi.org/10.2337/db06-0753

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Sulfonylurea Compounds Uncouple the Glucose Dependence of the Insulinotropic Effect of Glucagon-Like Peptide 1
Jocelyn de Heer and Jens J. Holst

Diabetes 2007 Feb; 56 (2): 438-443. https://doi.org/10.2337/db06-0738

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Complications

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Salicylate-Based Anti-Inflammatory Drugs Inhibit the Early Lesion of Diabetic Retinopathy
Ling Zheng, Scott J. Howell, Denise A. Hatala, Kun Huang and Timothy S. Kern

Diabetes 2007 Feb; 56 (2): 337-345. https://doi.org/10.2337/db06-0789

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Deletion of Protein Kinase C-β Isoform In Vivo Reduces Renal Hypertrophy but Not Albuminuria in the Streptozotocin-Induced Diabetic Mouse Model
Matthias Meier, Joon-Keun Park, Daniel Overheu, Torsten Kirsch, Carsten Lindschau, Faikah Gueler, Michael Leitges, Jan Menne and Hermann Haller

Diabetes 2007 Feb; 56 (2): 346-354. https://doi.org/10.2337/db06-0891

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Treatment of Streptozotocin-Induced Diabetic Rats With AVE7688, a Vasopeptidase InhibitorEffect on Vascular and Neural Disease
Eric P. Davidson, Travis L. Kleinschmidt, Christine L. Oltman, Donald D. Lund and Mark A. Yorek

Diabetes 2007 Feb; 56 (2): 355-362. https://doi.org/10.2337/db06-1180

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Macrophage Scavenger Receptor-A–Deficient Mice Are Resistant Against Diabetic Nephropathy Through Amelioration of Microinflammation
Hitomi Kataoka Usui, Kenichi Shikata, Motofumi Sasaki, Shinichi Okada, Mitsuhiro Matsuda, Yasushi Shikata, Daisuke Ogawa, Yuichi Kido, Ryo Nagase, Kosuke Yozai, Sakiko Ohga, Atsuhito Tone, Jun Wada, Motohiro Takeya, Seikoh Horiuchi, Tatsuhiko Kodama and Hirofumi Makino

Diabetes 2007 Feb; 56 (2): 363-372. https://doi.org/10.2337/db06-0359

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Topical Administration of Nepafenac Inhibits Diabetes-Induced Retinal Microvascular Disease and Underlying Abnormalities of Retinal Metabolism and Physiology
Timothy S. Kern, Casey M. Miller, Yunpeng Du, Ling Zheng, Susanne Mohr, Sherry L. Ball, M. Kim, Jeffrey A. Jamison and David P. Bingaman

Diabetes 2007 Feb; 56 (2): 373-379. https://doi.org/10.2337/db05-1621

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Evidence for a Role of Transforming Growth Factor (TGF)-β1 in the Induction of Postglomerular Albuminuria in Diabetic NephropathyAmelioration by Soluble TGF-β Type II Receptor
Leileata M. Russo, Elisabetta del Re, Dennis Brown and Herbert Y. Lin

Diabetes 2007 Feb; 56 (2): 380-388. https://doi.org/10.2337/db06-1018

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Alterations of Adenine Nucleotide Metabolism and Function of Blood Platelets in Patients With Diabetes
Anna Michno, Hanna Bielarczyk, Tadeusz Pawełczyk, Agnieszka Jankowska-Kulawy, Joanna Klimaszewska and Andrzej Szutowicz

Diabetes 2007 Feb; 56 (2): 462-467. https://doi.org/10.2337/db06-0390

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Impact of Type 2 Diabetes on Nitric Oxide and Adrenergic Modulation of Myocardial Perfusion
Mette M. Madsen, Hanne M. Søndergaard, Morten Bøttcher, Niels H. Buus, Ole Schmitz, Hans E. Bøtker and Torsten T. Nielsen

Diabetes 2007 Feb; 56 (2): 468-475. https://doi.org/10.2337/db06-0635

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High Glucose, High Insulin, and Their Combination Rapidly Induce Laminin-β1 Synthesis by Regulation of mRNA Translation in Renal Epithelial Cells
Meenalakshmi M. Mariappan, Denis Feliers, Srinivas Mummidi, Goutam Ghosh Choudhury and Balakuntalam S. Kasinath

Diabetes 2007 Feb; 56 (2): 476-485. https://doi.org/10.2337/db05-1334

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Brief Reports

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Haplotypes of Transcription Factor 7–Like 2 (TCF7L2) Gene and Its Upstream Region Are Associated With Type 2 Diabetes and Age of Onset in Mexican Americans
Donna M. Lehman, Kelly J. Hunt, Robin J. Leach, Jeanette Hamlington, Rector Arya, Hanna E. Abboud, Ravindranath Duggirala, John Blangero, Harald H.H. Göring and Michael P. Stern

Diabetes 2007 Feb; 56 (2): 389-393. https://doi.org/10.2337/db06-0860

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P2 Promoter Variants of the Hepatocyte Nuclear Factor 4α Gene Are Associated With Type 2 Diabetes in Mexican Americans
Donna M. Lehman, Dawn K. Richardson, Chris P. Jenkinson, Kelly J. Hunt, Thomas D. Dyer, Robin J. Leach, Rector Arya, Hanna E. Abboud, John Blangero, Ravindranath Duggirala and Michael P. Stern

Diabetes 2007 Feb; 56 (2): 513-517. https://doi.org/10.2337/db06-0881

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Women With Mitochondrial Haplogroup N9a Are Protected Against Metabolic Syndrome
Masashi Tanaka, Noriyuki Fuku, Yutaka Nishigaki, Hitoshi Matsuo, Tomonori Segawa, Sachiro Watanabe, Kimihiko Kato, Kiyoshi Yoko, Masafumi Ito, Yoshinori Nozawa and Yoshiji Yamada

Diabetes 2007 Feb; 56 (2): 518-521. https://doi.org/10.2337/db06-1105

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PTPN22 R620W Functional Variant in Type 1 Diabetes and Autoimmunity Related Traits
Claude Chelala, Sabine Duchatelet, Marie-Line Joffret, Regine Bergholdt, Danièle Dubois-Laforgue, Pegah Ghandil, Flemming Pociot, Sophie Caillat-Zucman, José Timsit and Cécile Julier

Diabetes 2007 Feb; 56 (2): 522-526. https://doi.org/10.2337/db06-0942

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Myocardial Uptake of Circulating Triglycerides in Nondiabetic Patients With Heart Disease
Robert H. Nelson, Abhiram Prasad, Amir Lerman and John M. Miles

Diabetes 2007 Feb; 56 (2): 527-530. https://doi.org/10.2337/db06-1552

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Type 2 Diabetes–Associated Missense Polymorphisms KCNJ11 E23K and ABCC8 A1369S Influence Progression to Diabetes and Response to Interventions in the Diabetes Prevention Program
Jose C. Florez, Kathleen A. Jablonski, Steven E. Kahn, Paul W. Franks, Dana Dabelea, Richard F. Hamman, William C. Knowler, David M. Nathan, David Altshuler and , for the Diabetes Prevention Program Research Groupy

Diabetes 2007 Feb; 56 (2): 531-536. https://doi.org/10.2337/db06-0966

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Linkage and Association Analyses of Type 2 Diabetes/Impaired Glucose Metabolism and Adiponectin Serum Levels in Japanese Americans From Hawaii
Ilija P. Kovac, Richard J. Havlik, Daniel Foley, Rita Peila, Dena Hernandez, Fabienne Wavrant-De Vrièze, Andrew Singleton, Josephine Egan, Dennis Taub, Beatriz Rodriguez, Kamal Masaki, J. David Curb, Wilfred Y. Fujimoto and Alexander F. Wilson

Diabetes 2007 Feb; 56 (2): 537-540. https://doi.org/10.2337/db06-0443

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Signal Transduction

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Ceramide- and Oxidant-Induced Insulin Resistance Involve Loss of Insulin-Dependent Rac-Activation and Actin Remodeling in Muscle Cells
Lellean JeBailey, Oshrit Wanono, Wenyan Niu, Jessica Roessler, Assaf Rudich and Amira Klip

Diabetes 2007 Feb; 56 (2): 394-403. https://doi.org/10.2337/db06-0823

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Protein–Tyrosine Phosphatase 1B–Deficient Myocytes Show Increased Insulin Sensitivity and Protection Against Tumor Necrosis Factor-α–Induced Insulin Resistance
Iria Nieto-Vazquez, Sonia Fernández-Veledo, Cristina de Alvaro, Cristina M. Rondinone, Angela M. Valverde and Margarita Lorenzo

Diabetes 2007 Feb; 56 (2): 404-413. https://doi.org/10.2337/db06-0989

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The Rab GTPase-Activating Protein AS160 Integrates Akt, Protein Kinase C, and AMP-Activated Protein Kinase Signals Regulating GLUT4 Traffic
Farah S.L. Thong, Philip J. Bilan and Amira Klip

Diabetes 2007 Feb; 56 (2): 414-423. https://doi.org/10.2337/db06-0900

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Immunology and Transplantation

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Cellular Expression Requirements for Inhibition of Type 1 Diabetes by a Dominantly Protective Major Histocompatibility Complex Haplotype
Yi-Guang Chen, Pablo A. Silveira, Melissa A. Osborne, Harold D. Chapman and David V. Serreze

Diabetes 2007 Feb; 56 (2): 424-430. https://doi.org/10.2337/db06-1303

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Pathophysiology

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Pancreatic Lipomatosis Is a Structural Marker in Nondiabetic Children With Mutations in Carboxyl-Ester Lipase
Helge Ræder, Ingfrid S. Haldorsen, Lars Ersland, Renate Grüner, Torfinn Taxt, Oddmund Søvik, Anders Molven and Pål R. Njølstad

Diabetes 2007 Feb; 56 (2): 444-449. https://doi.org/10.2337/db06-0859

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Tumor Necrosis Factor-α Induces Intestinal Insulin Resistance and Stimulates the Overproduction of Intestinal Apolipoprotein B48-Containing Lipoproteins
Bolin Qin, Wei Qiu, Rita Kohen Avramoglu and Khosrow Adeli

Diabetes 2007 Feb; 56 (2): 450-461. https://doi.org/10.2337/db06-0518

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Pharmacology and Therapeutics

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Oral Insulin-Mimetic Compounds That Act Independently of Insulin
Silvia García-Vicente, Francesc Yraola, Luc Marti, Elena González-Muñoz, María José García-Barrado, Carles Cantó, Anna Abella, Sandy Bour, Rafael Artuch, Cristina Sierra, Nuria Brandi, Christian Carpéné, Julio Moratinos, Marta Camps, Manuel Palacín, Xavier Testar, Anna Gumà, Fernando Albericio, Miriam Royo, Alec Mian and Antonio Zorzano

Diabetes 2007 Feb; 56 (2): 486-493. https://doi.org/10.2337/db06-0269

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Genetics

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A Possible Role for the PPARG Pro12Ala Polymorphism in Preterm Birth
Aline Meirhaeghe, Colin A.G. Boreham, Liam J. Murray, Florence Richard, George Davey Smith, Ian S. Young and Philippe Amouyel

Diabetes 2007 Feb; 56 (2): 494-498. https://doi.org/10.2337/db06-0915

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Tag Polymorphisms at the A20 (TNFAIP3) Locus Are Associated With Lower Gene Expression and Increased Risk of Coronary Artery Disease in Type 2 Diabetes
Watip Boonyasrisawat, Delphine Eberle, Simonetta Bacci, Yuan-Yuan Zhang, David Nolan, Ernest V. Gervino, Michael T. Johnstone, Vincenzo Trischitta, Steven E. Shoelson and Alessandro Doria

Diabetes 2007 Feb; 56 (2): 499-505. https://doi.org/10.2337/db06-0946

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Genetic Reconstitution of Autoimmune Type 1 Diabetes With Two Major Susceptibility Genes in the Rat
Norihide Yokoi, Chihiro Hayashi, Yuuka Fujiwara, He-Yao Wang and Susumu Seino

Diabetes 2007 Feb; 56 (2): 506-512. https://doi.org/10.2337/db06-1027

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Perspectives in Diabetes

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Diabetes and Suppressors of Cytokine Signaling Proteins
Sif G. Rønn, Nils Billestrup and Thomas Mandrup-Poulsen

Diabetes 2007 Feb; 56 (2): 541-548. https://doi.org/10.2337/db06-1068

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Erratum

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Errata
Diabetes 2007 Feb; 56 (2): 549. https://doi.org/10.2337/db07-er02

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Table of Contents

Obesity Studies

Islet Studies

Complications

Brief Reports

Signal Transduction

Immunology and Transplantation

Pathophysiology

Pharmacology and Therapeutics

Genetics

Perspectives in Diabetes

Erratum

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