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Islet Studies

Cx36-Mediated Coupling Reduces β-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics

  1. Stephan Speier1,
  2. Asllan Gjinovci2,
  3. Anne Charollais2,
  4. Paolo Meda2 and
  5. Marjan Rupnik1
  1. 1Neuroendocrinology, European Neuroscience Institute Göttingen, Göttingen, Germany
  2. 2Department of Cell Physiology and Metabolism, University of Geneva, Genève, Switzerland
  1. Address correspondence and reprint requests to Stephan Speier, The Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital L1, Stockholm, Sweden. E-mail: stephan.speier{at}ki.se
Diabetes 2007 Apr; 56(4): 1078-1086. https://doi.org/10.2337/db06-0232
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Article Information

vol. 56 no. 4 1078-1086
DOI 
https://doi.org/10.2337/db06-0232
PubMed 
17395748

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • December 15, 2006
  • February 19, 2006
  • Published in print March 29, 2007.

Copyright & Usage 
DIABETES

Author Information

  1. Stephan Speier1,
  2. Asllan Gjinovci2,
  3. Anne Charollais2,
  4. Paolo Meda2 and
  5. Marjan Rupnik1
  1. 1Neuroendocrinology, European Neuroscience Institute Göttingen, Göttingen, Germany
  2. 2Department of Cell Physiology and Metabolism, University of Geneva, Genève, Switzerland
  1. Address correspondence and reprint requests to Stephan Speier, The Rolf Luft Center for Diabetes Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital L1, Stockholm, Sweden. E-mail: stephan.speier{at}ki.se
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Cx36-Mediated Coupling Reduces β-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics
Stephan Speier, Asllan Gjinovci, Anne Charollais, Paolo Meda, Marjan Rupnik
Diabetes Apr 2007, 56 (4) 1078-1086; DOI: 10.2337/db06-0232

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Cx36-Mediated Coupling Reduces β-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics
Stephan Speier, Asllan Gjinovci, Anne Charollais, Paolo Meda, Marjan Rupnik
Diabetes Apr 2007, 56 (4) 1078-1086; DOI: 10.2337/db06-0232
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  • Pancreatic β-Cell–Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion
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