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Table of Contents

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June 01 2007; volume 56 issue 6

Banting Lecture 2006

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    Orchestration of Glucose HomeostasisFrom a Small Acorn to the California Oak
    Richard N. Bergman
    Diabetes 2007 Jun; 56 (6): 1489-1501. https://doi.org/10.2337/db07-9903
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Perspectives in Diabetes

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    (How) Can We Prevent Type 2 Diabetes?
    Thomas A. Buchanan
    Diabetes 2007 Jun; 56 (6): 1502-1507. https://doi.org/10.2337/db07-0140
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Signal Transduction

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    Global Assessment of Regulation of Phosphorylation of Insulin Receptor Substrate-1 by Insulin In Vivo in Human Muscle
    Zhengping Yi, Paul Langlais, Elena A. De Filippis, Moulun Luo, Charles R. Flynn, Stefanie Schroeder, Susan T. Weintraub, Rebekka Mapes and Lawrence J. Mandarino
    Diabetes 2007 Jun; 56 (6): 1508-1516. https://doi.org/10.2337/db06-1355
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    The STAT5A-Mediated Induction of Pyruvate Dehydrogenase Kinase 4 Expression by Prolactin or Growth Hormone in Adipocytes
    Ursula A. White, Ann A. Coulter, Tiffany K. Miles and Jacqueline M. Stephens
    Diabetes 2007 Jun; 56 (6): 1623-1629. https://doi.org/10.2337/db06-1286
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    Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle
    Stephan Glund, Atul Deshmukh, Yun Chau Long, Theodore Moller, Heikki A. Koistinen, Kenneth Caidahl, Juleen R. Zierath and Anna Krook
    Diabetes 2007 Jun; 56 (6): 1630-1637. https://doi.org/10.2337/db06-1733
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    Growth Hormone Regulation of p85α Expression and Phosphoinositide 3-Kinase Activity in Adipose TissueMechanism for Growth Hormone–Mediated Insulin Resistance
    Juan-Pablo del Rincon, Keiji Iida, Bruce D. Gaylinn, Carrie E. McCurdy, J. Wayne Leitner, Linda A. Barbour, John J. Kopchick, Jacob E. Friedman, Boris Draznin and Michael O. Thorner
    Diabetes 2007 Jun; 56 (6): 1638-1646. https://doi.org/10.2337/db06-0299
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Obesity Studies

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    Adipogenesis in Obesity Requires Close Interplay Between Differentiating Adipocytes, Stromal Cells, and Blood Vessels
    Satoshi Nishimura, Ichiro Manabe, Mika Nagasaki, Yumiko Hosoya, Hiroshi Yamashita, Hideo Fujita, Mitsuru Ohsugi, Kazuyuki Tobe, Takashi Kadowaki, Ryozo Nagai and Seiryo Sugiura
    Diabetes 2007 Jun; 56 (6): 1517-1526. https://doi.org/10.2337/db06-1749
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    Increasing Dietary Leucine Intake Reduces Diet-Induced Obesity and Improves Glucose and Cholesterol Metabolism in Mice via Multimechanisms
    Yiying Zhang, Kaiying Guo, Robert E. LeBlanc, Daniella Loh, Gary J. Schwartz and Yi-Hao Yu
    Diabetes 2007 Jun; 56 (6): 1647-1654. https://doi.org/10.2337/db07-0123
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    Omentin Plasma Levels and Gene Expression Are Decreased in Obesity
    Celia M. de Souza Batista, Rong-Ze Yang, Mi-Jeong Lee, Nicole M. Glynn, Dao-Zhan Yu, Jessica Pray, Kelechi Ndubuizu, Susheel Patil, Alan Schwartz, Mark Kligman, Susan K. Fried, Da-Wei Gong, Alan R. Shuldiner, Toni I. Pollin and John C. McLenithan
    Diabetes 2007 Jun; 56 (6): 1655-1661. https://doi.org/10.2337/db06-1506
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    PPARα Agonists Suppress Osteopontin Expression in Macrophages and Decrease Plasma Levels in Patients With Type 2 Diabetes
    Takafumi Nakamachi, Takashi Nomiyama, Florence Gizard, Elizabeth B. Heywood, Karrie L. Jones, Yue Zhao, Lucia Fuentes, Kohzo Takebayashi, Yoshimasa Aso, Bart Staels, Toshihiko Inukai and Dennis Bruemmer
    Diabetes 2007 Jun; 56 (6): 1662-1670. https://doi.org/10.2337/db06-1177
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    Glucagon-Like Peptide-1 Gene Therapy in Obese Diabetic Mice Results in Long-Term Cure of Diabetes by Improving Insulin Sensitivity and Reducing Hepatic Gluconeogenesis
    Young-Sun Lee, Seungjin Shin, Toshikatsu Shigihara, Eunsil Hahm, Meng-Ju Liu, Jaeseok Han, Ji-Won Yoon and Hee-Sook Jun
    Diabetes 2007 Jun; 56 (6): 1671-1679. https://doi.org/10.2337/db06-1182
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    Body Size and Shape Changes and the Risk of Diabetes in the Diabetes Prevention Program
    Wilfred Y. Fujimoto, Kathleen A. Jablonski, George A. Bray, Andrea Kriska, Elizabeth Barrett-Connor, Steven Haffner, Robert Hanson, James O. Hill, Van Hubbard, E. Stamm and F. Xavier Pi-Sunyer
    Diabetes 2007 Jun; 56 (6): 1680-1685. https://doi.org/10.2337/db07-0009
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Immunology and Transplantation

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    GAD Autoantibody Affinity and Epitope Specificity Identify Distinct Immunization Profiles in Children at Risk for Type 1 Diabetes
    Anja Mayr, Michael Schlosser, Natalie Grober, Heidrun Kenk, Anette G. Ziegler, Ezio Bonifacio and Peter Achenbach
    Diabetes 2007 Jun; 56 (6): 1527-1533. https://doi.org/10.2337/db06-1715
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    Transient Upregulation of Indoleamine 2,3-Dioxygenase in Dendritic Cells by Human Chorionic Gonadotropin Downregulates Autoimmune Diabetes
    Aito Ueno, Suzanne Cho, Lu Cheng, Jianxiong Wang, Sheng Hou, Hiroko Nakano, Pere Santamaria and Yang Yang
    Diabetes 2007 Jun; 56 (6): 1686-1693. https://doi.org/10.2337/db06-1727
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Islet Studies

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    Chronic Activation of Liver X Receptor Induces β-Cell Apoptosis Through Hyperactivation of LipogenesisLiver X Receptor–Mediated Lipotoxicity in Pancreatic β-Cells
    Sung Sik Choe, A Hyun Choi, Joo-Won Lee, Kang Ho Kim, Jun-Jae Chung, Jiyoung Park, Kyeong-Min Lee, Keun-Gyu Park, In-Kyu Lee and Jae Bum Kim
    Diabetes 2007 Jun; 56 (6): 1534-1543. https://doi.org/10.2337/db06-1059
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    Implantation Site–Dependent Dysfunction of Transplanted Pancreatic Islets
    Joey Lau, Göran Mattsson, Carina Carlsson, Daniel Nyqvist, Martin Köhler, Per-Olof Berggren, Leif Jansson and Per-Ola Carlsson
    Diabetes 2007 Jun; 56 (6): 1544-1550. https://doi.org/10.2337/db06-1258
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    Glucose-Dependent Modulation of Insulin Secretion and Intracellular Calcium Ions by GKA50, a Glucokinase Activator
    Daniel Johnson, Ruth M. Shepherd, Debra Gill, Tracy Gorman, David M. Smith and Mark J. Dunne
    Diabetes 2007 Jun; 56 (6): 1694-1702. https://doi.org/10.2337/db07-0026
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    Contribution of Hepatic and Extrahepatic Insulin Resistance to the Pathogenesis of Impaired Fasting GlucoseRole of Increased Rates of Gluconeogenesis
    Gerlies Bock, Elizabeth Chittilapilly, Rita Basu, Gianna Toffolo, Claudio Cobelli, Visvanathan Chandramouli, Bernard R. Landau and Robert A. Rizza
    Diabetes 2007 Jun; 56 (6): 1703-1711. https://doi.org/10.2337/db06-1776
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Pathophysiology

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    Downregulation of GLP-1 and GIP Receptor Expression by HyperglycemiaPossible Contribution to Impaired Incretin Effects in Diabetes
    Gang Xu, Hideaki Kaneto, D. Ross Laybutt, Valerie F. Duvivier-Kali, Nitin Trivedi, Kiyoshi Suzuma, George L. King, Gordon C. Weir and Susan Bonner-Weir
    Diabetes 2007 Jun; 56 (6): 1551-1558. https://doi.org/10.2337/db06-1033
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    Paradoxical Elevation of High–Molecular Weight Adiponectin in Acquired Extreme Insulin Resistance Due to Insulin Receptor Antibodies
    Robert K. Semple, Nils H. Halberg, Keith Burling, Maria A. Soos, Todd Schraw, Jian'an Luan, Elaine K. Cochran, David B. Dunger, Nicholas J. Wareham, Philipp E. Scherer, Phillip Gorden and Stephen O'Rahilly
    Diabetes 2007 Jun; 56 (6): 1712-1717. https://doi.org/10.2337/db06-1665
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Complications

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    High Glucose Impairs Early and Late Endothelial Progenitor Cells by Modifying Nitric Oxide–Related but Not Oxidative Stress–Mediated Mechanisms
    Yung-Hsiang Chen, Shing-Jong Lin, Feng-Yen Lin, Tao-Cheng Wu, Chen-Rong Tsao, Po-Hsun Huang, Po-Len Liu, Yuh-Lien Chen and Jaw-Wen Chen
    Diabetes 2007 Jun; 56 (6): 1559-1568. https://doi.org/10.2337/db06-1103
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    Pathogenesis of Spinally Mediated Hyperalgesia in Diabetes
    Khara M. Ramos, Yun Jiang, Camilla I. Svensson and Nigel A. Calcutt
    Diabetes 2007 Jun; 56 (6): 1569-1576. https://doi.org/10.2337/db06-1269
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    Genome-Wide Scans for Diabetic Nephropathy and Albuminuria in Multiethnic PopulationsThe Family Investigation of Nephropathy and Diabetes (FIND)
    Sudha K. Iyengar, Hanna E. Abboud, Katrina A.B. Goddard, Mohammed F. Saad, Sharon G. Adler, Nedal H. Arar, Donald W. Bowden, Ravi Duggirala, Robert C. Elston, Robert L. Hanson, Eli Ipp, W.H. Linda Kao, Paul L. Kimmel, Michael J. Klag, William C. Knowler, Lucy A. Meoni, Robert G. Nelson, Susanne B. Nicholas, Madeleine V. Pahl, Rulan S. Parekh, Shannon R.E. Quade, Stephen S. Rich, Jerome I. Rotter, Marina Scavini, Jeffrey R. Schelling, John R. Sedor, Ashwini R. Sehgal, Vallabh O. Shah, Michael W. Smith, Kent D. Taylor, Cheryl A. Winkler, Philip G. Zager and Barry I. Freedman
    Diabetes 2007 Jun; 56 (6): 1577-1585. https://doi.org/10.2337/db06-1154
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    Variations in Adiponectin Receptor Genes and Susceptibility to Type 2 Diabetes in WomenA Tagging–Single Nucleotide Polymorphism Haplotype Analysis
    Lu Qi, Alessandro Doria, Elena Giorgi and Frank B. Hu
    Diabetes 2007 Jun; 56 (6): 1586-1591. https://doi.org/10.2337/db06-1447
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    Prevalence and Prognostic Impact of Subclinical Cardiovascular Disease in Individuals With the Metabolic Syndrome and Diabetes
    Erik Ingelsson, Lisa M. Sullivan, Joanne M. Murabito, Caroline S. Fox, Emelia J. Benjamin, Joseph F. Polak, James B. Meigs, Michelle J. Keyes, Christopher J. O'Donnell, Thomas J. Wang, Ralph B. D'Agostino, Philip A. Wolf and Ramachandran S. Vasan
    Diabetes 2007 Jun; 56 (6): 1718-1726. https://doi.org/10.2337/db07-0078
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Metabolism

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    Mitochondrial Respiration Is Decreased in Skeletal Muscle of Patients With Type 2 Diabetes
    Martin Mogensen, Kent Sahlin, Maria Fernström, Dorte Glintborg, Birgitte F. Vind, Henning Beck-Nielsen and Kurt Højlund
    Diabetes 2007 Jun; 56 (6): 1592-1599. https://doi.org/10.2337/db06-0981
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    The Mammalian Target of Rapamycin Pathway Regulates Nutrient-Sensitive Glucose Uptake in Man
    Michael Krebs, Barbara Brunmair, Attila Brehm, Michaela Artwohl, Julia Szendroedi, Peter Nowotny, Erich Roth, Clemens Fürnsinn, Miriam Promintzer, Christian Anderwald, Martin Bischof and Michael Roden
    Diabetes 2007 Jun; 56 (6): 1600-1607. https://doi.org/10.2337/db06-1016
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    Resistance Exercise and Insulin Regulate AS160 and Interaction With 14-3-3 in Human Skeletal Muscle
    Kirsten F. Howlett, Kei Sakamoto, Andrew Garnham, David Cameron-Smith and Mark Hargreaves
    Diabetes 2007 Jun; 56 (6): 1608-1614. https://doi.org/10.2337/db06-1398
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    Aerobic Exercise Overcomes the Age-Related Insulin Resistance of Muscle Protein Metabolism by Improving Endothelial Function and Akt/Mammalian Target of Rapamycin Signaling
    Satoshi Fujita, Blake B. Rasmussen, Jerson G. Cadenas, Micah J. Drummond, Erin L. Glynn, Fred R. Sattler and Elena Volpi
    Diabetes 2007 Jun; 56 (6): 1615-1622. https://doi.org/10.2337/db06-1566
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Brief Reports

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    Reduction in Microalbuminuria as an Integrated Indicator for Renal and Cardiovascular Risk Reduction in Patients With Type 2 Diabetes
    Shin-ichi Araki, Masakazu Haneda, Daisuke Koya, Hideki Hidaka, Toshiro Sugimoto, Motohide Isono, Keiji Isshiki, Masami Chin-Kanasaki, Takashi Uzu and Atsunori Kashiwagi
    Diabetes 2007 Jun; 56 (6): 1727-1730. https://doi.org/10.2337/db06-1646
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    A Novel Susceptibility Locus on Rat Chromosome 8 Affects Spontaneous but Not Experimentally Induced Type 1 Diabetes
    Robert H. Wallis, KeSheng Wang, Dominika Dabrowski, Leili Marandi, Terri Ning, Eugene Hsieh, Andrew D. Paterson, John P. Mordes, Elisabeth P. Blankenhorn and Philippe Poussier
    Diabetes 2007 Jun; 56 (6): 1731-1736. https://doi.org/10.2337/db06-1790
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    New ABCC8 Mutations in Relapsing Neonatal Diabetes and Clinical Features
    Martine Vaxillaire, Aurélie Dechaume, Kanetee Busiah, Hélène Cavé, Sabrina Pereira, Raphael Scharfmann, Guiomar Perez de Nanclares, Luis Castano, Philippe Froguel and Michel Polak
    Diabetes 2007 Jun; 56 (6): 1737-1741. https://doi.org/10.2337/db06-1540
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    Quantitative Trait Loci for Fasting Glucose in Young Europeans Replicate Previous Findings for Type 2 Diabetes in 2q23–24 and Other Locations
    Delphine Fradin, Simon Heath, Mark Lathrop and Pierre Bougnères
    Diabetes 2007 Jun; 56 (6): 1742-1745. https://doi.org/10.2337/db06-1329
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Erratum

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    Errata
    Diabetes 2007 Jun; 56 (6): 1746. https://doi.org/10.2337/db07-er06
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    Errata
    Diabetes 2007 Jun; 56 (6): 1747. https://doi.org/10.2337/db07-er06a
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June 2007, 56(6)
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  • Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis
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  • A Polymorphism in the Glucocorticoid Receptor Gene, Which Decreases Sensitivity to Glucocorticoids In Vivo, Is Associated With Low Insulin and Cholesterol Levels
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