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Table of Contents

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September 01 2007; volume 56 issue 9

Metabolism

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    Neuregulins Increase Mitochondrial Oxidative Capacity and Insulin Sensitivity in Skeletal Muscle Cells
    Carles Cantó, Sara Pich, José C. Paz, Rosario Sanches, Vicente Martínez, Meritxell Orpinell, Manuel Palacín, Antonio Zorzano and Anna Gumà
    Diabetes 2007 Sep; 56 (9): 2185-2193. https://doi.org/10.2337/db06-1726
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    Contraction Stimulates Nitric Oxide–Independent Microvascular Recruitment and Increases Muscle Insulin Uptake
    April C. Inyard, Lucy H. Clerk, Michelle A. Vincent and Eugene J. Barrett
    Diabetes 2007 Sep; 56 (9): 2194-2200. https://doi.org/10.2337/db07-0020
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    Metallothionein Prevents High-Fat Diet–Induced Cardiac Contractile DysfunctionRole of Peroxisome Proliferator–Activated Receptor γ Coactivator 1α and Mitochondrial Biogenesis
    Feng Dong, Qun Li, Nair Sreejayan, Jennifer M. Nunn and Jun Ren
    Diabetes 2007 Sep; 56 (9): 2201-2212. https://doi.org/10.2337/db06-1596
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    Physiological Hyperinsulinemia Has No Detectable Effect on Access of Macromolecules to Insulin-Sensitive Tissues in Healthy Humans
    Heinz Weinhandl, Christoph Pachler, Julia K. Mader, Dimas Ikeoka, Agnes Mautner, Andreas Falk, Maria Suppan, Thomas R. Pieber and Martin Ellmerer
    Diabetes 2007 Sep; 56 (9): 2213-2217. https://doi.org/10.2337/db07-0238
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Signal Transduction

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    Characterization of a Protein Kinase B Inhibitor In Vitro and in Insulin-Treated Liver Cells
    Lisa Logie, Antonio J. Ruiz-Alcaraz, Michael Keane, Yvonne L. Woods, Jennifer Bain, Rudolfo Marquez, Dario R. Alessi and Calum Sutherland
    Diabetes 2007 Sep; 56 (9): 2218-2227. https://doi.org/10.2337/db07-0343
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    AMP Kinase Activation Increases Glucose Uptake, Decreases Apoptosis, and Improves Pregnancy Outcome in Embryos Exposed to High IGF-I Concentrations
    Grace S. Eng, Rachael A. Sheridan, Amanda Wyman, Maggie M.-Y. Chi, Kristin P. Bibee, Emily S. Jungheim and Kelle H. Moley
    Diabetes 2007 Sep; 56 (9): 2228-2234. https://doi.org/10.2337/db07-0074
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    Normalization of Prandial Blood Glucose and Improvement of Glucose Tolerance by Liver-Specific Inhibition of SH2 Domain–Containing Inositol Phosphatase 2 (SHIP2) in Diabetic KKAy Mice SHIP2 Inhibition Causes Insulin-Mimetic Effects on Glycogen Metabolism, Gluconeogenesis, and Glycolysis
    Rolf Grempler, Darya Zibrova, Corinna Schoelch, André van Marle, Joerg F. Rippmann and Norbert Redemann
    Diabetes 2007 Sep; 56 (9): 2235-2241. https://doi.org/10.2337/db06-1660
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Obesity Studies

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    Absence of CC Chemokine Ligand 2 Does Not Limit Obesity-Associated Infiltration of Macrophages Into Adipose Tissue
    Karen E. Inouye, Hang Shi, Jane K. Howard, Christine H. Daly, Graham M. Lord, Barrett J. Rollins and Jeffrey S. Flier
    Diabetes 2007 Sep; 56 (9): 2242-2250. https://doi.org/10.2337/db07-0425
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Immunology and Transplantation

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    Bone Marrow Is a Preferential Homing Site for Autoreactive T-Cells in Type 1 Diabetes
    Ruobing Li, Nicolas Perez, Subha Karumuthil-Melethil and Chenthamarakshan Vasu
    Diabetes 2007 Sep; 56 (9): 2251-2259. https://doi.org/10.2337/db07-0502
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    Adipocyte-Derived Serum Amyloid A3 and Hyaluronan Play a Role in Monocyte Recruitment and Adhesion
    Chang Yeop Han, Savitha Subramanian, Christina K. Chan, Mohamed Omer, Tsuyoshi Chiba, Thomas N. Wight and Alan Chait
    Diabetes 2007 Sep; 56 (9): 2260-2273. https://doi.org/10.2337/db07-0218
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    Angiopoietin-1 Production in Islets Improves Islet Engraftment and Protects Islets From Cytokine-Induced Apoptosis
    Dongming Su, Nan Zhang, Jing He, Shen Qu, Sandra Slusher, Rita Bottino, Suzanne Bertera, Jonathan Bromberg and H. Henry Dong
    Diabetes 2007 Sep; 56 (9): 2274-2283. https://doi.org/10.2337/db07-0371
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Islet Studies

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    Impairment of the Ubiquitin-Proteasome Pathway Is a Downstream Endoplasmic Reticulum Stress Response Induced by Extracellular Human Islet Amyloid Polypeptide and Contributes to Pancreatic β-Cell Apoptosis
    Sílvia Casas, Ramon Gomis, Fiona M. Gribble, Jordi Altirriba, Sakari Knuutila and Anna Novials
    Diabetes 2007 Sep; 56 (9): 2284-2294. https://doi.org/10.2337/db07-0178
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    Metabolic Mechanisms of Failure of Intraportally Transplanted Pancreatic β-Cells in RatsRole of Lipotoxicity and Prevention by Leptin
    Young Lee, Mariella Ravazzola, Byung-Hyun Park, Yuriy K. Bashmakov, Lelio Orci and Roger H. Unger
    Diabetes 2007 Sep; 56 (9): 2295-2301. https://doi.org/10.2337/db07-0460
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    Distinct In Vivo Roles of Caspase-8 in β-Cells in Physiological and Diabetes Models
    Nicole Liadis, Leonardo Salmena, Edwin Kwan, Panteha Tajmir, Stephanie A. Schroer, Anna Radziszewska, Xie Li, Laura Sheu, Mohamed Eweida, Shilong Xu, Herbert Y. Gaisano, Razqallah Hakem and Minna Woo
    Diabetes 2007 Sep; 56 (9): 2302-2311. https://doi.org/10.2337/db06-1771
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    Normal Relationship of β- and Non–β-Cells Not Needed for Successful Islet Transplantation
    Aileen J.F. King, Justin R. Fernandes, Jennifer Hollister-Lock, Cameron E. Nienaber, Susan Bonner-Weir and Gordon C. Weir
    Diabetes 2007 Sep; 56 (9): 2312-2318. https://doi.org/10.2337/db07-0191
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    Ghrelin Uses Gαi2 and Activates Voltage-Dependent K+ Channels to Attenuate Glucose-Induced Ca2+ Signaling and Insulin Release in Islet β-CellsNovel Signal Transduction of Ghrelin
    Katsuya Dezaki, Masafumi Kakei and Toshihiko Yada
    Diabetes 2007 Sep; 56 (9): 2319-2327. https://doi.org/10.2337/db07-0345
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    Direct Effect of Cholesterol on Insulin SecretionA Novel Mechanism for Pancreatic β-Cell Dysfunction
    Mingming Hao, W. Steven Head, Subhadra C. Gunawardana, Alyssa H. Hasty and David W. Piston
    Diabetes 2007 Sep; 56 (9): 2328-2338. https://doi.org/10.2337/db07-0056
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    Congenital Hyperinsulinism–Associated ABCC8 Mutations That Cause Defective Trafficking of ATP-Sensitive K+ ChannelsIdentification and Rescue
    Fei-Fei Yan, Yu-Wen Lin, Courtney MacMullen, Arupa Ganguly, Charles A. Stanley and Show-Ling Shyng
    Diabetes 2007 Sep; 56 (9): 2339-2348. https://doi.org/10.2337/db07-0150
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Pathophysiology

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    Reduced Expression of Nuclear-Encoded Genes Involved in Mitochondrial Oxidative Metabolism in Skeletal Muscle of Insulin-Resistant Women With Polycystic Ovary Syndrome
    Vibe Skov, Dorte Glintborg, Steen Knudsen, Thomas Jensen, Torben A. Kruse, Qihua Tan, Klaus Brusgaard, Henning Beck-Nielsen and Kurt Højlund
    Diabetes 2007 Sep; 56 (9): 2349-2355. https://doi.org/10.2337/db07-0275
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    Increased Number of Islet-Associated Macrophages in Type 2 Diabetes
    Jan A. Ehses, Aurel Perren, Elisabeth Eppler, Pascale Ribaux, John A. Pospisilik, Ranit Maor-Cahn, Xavier Gueripel, Helga Ellingsgaard, Marten K.J. Schneider, Gregoire Biollaz, Adriano Fontana, Manfred Reinecke, Francoise Homo-Delarche and Marc Y. Donath
    Diabetes 2007 Sep; 56 (9): 2356-2370. https://doi.org/10.2337/db06-1650
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Complications

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    The Vascular Ectonucleotidase ENTPD1 Is a Novel Renoprotective Factor in Diabetic Nephropathy
    David J. Friedman, Helmut G. Rennke, Eva Csizmadia, Keiichi Enjyoji and Simon C. Robson
    Diabetes 2007 Sep; 56 (9): 2371-2379. https://doi.org/10.2337/db06-1593
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    Proteolytic Degradation of VE-Cadherin Alters the Blood-Retinal Barrier in Diabetes
    Deepti Navaratna, Paul G. McGuire, Gina Menicucci and Arup Das
    Diabetes 2007 Sep; 56 (9): 2380-2387. https://doi.org/10.2337/db06-1694
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Genetics

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    Alcohol Consumption and Type 2 DiabetesInfluence of Genetic Variation in Alcohol Dehydrogenase
    Joline W.J. Beulens, Eric B. Rimm, Henk F.J. Hendriks, Frank B. Hu, JoAnn E. Manson, David J. Hunter and Kenneth J. Mukamal
    Diabetes 2007 Sep; 56 (9): 2388-2394. https://doi.org/10.2337/db07-0181
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Brief Reports

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    Hepatic Lipin 1β Expression Is Diminished in Insulin-Resistant Obese Subjects and Is Reactivated by Marked Weight Loss
    Michelle A. Croce, J. Christopher Eagon, Lori L. LaRiviere, Kevin M. Korenblat, Samuel Klein and Brian N. Finck
    Diabetes 2007 Sep; 56 (9): 2395-2399. https://doi.org/10.2337/db07-0480
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    Screening for Insulitis in Adult Autoantibody-Positive Organ Donors
    Peter In't Veld, Dirk Lievens, Joeri De Grijse, Zhidong Ling, Bart Van der Auwera, Miriam Pipeleers-Marichal, Frans Gorus and Daniel Pipeleers
    Diabetes 2007 Sep; 56 (9): 2400-2404. https://doi.org/10.2337/db07-0416
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    HLA-DPB1*0402 Protects Against Type 1A Diabetes Autoimmunity in the Highest Risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY Population
    Erin E. Baschal, Theresa A. Aly, Sunanda R. Babu, Maria S. Fernando, Liping Yu, Dongmei Miao, Katherine J. Barriga, Jill M. Norris, Janelle A. Noble, Henry A. Erlich, Marian J. Rewers and George S. Eisenbarth
    Diabetes 2007 Sep; 56 (9): 2405-2409. https://doi.org/10.2337/db07-0029
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    A CTG Polymorphism in the CNDP1 Gene Determines the Secretion of Serum Carnosinase in Cos-7–Transfected Cells
    Eva Riedl, Hannes Koeppel, Paul Brinkkoetter, Paula Sternik, Herbert Steinbeisser, Sibylle Sauerhoefer, Bart Janssen, Fokko J. van der Woude and Benito A. Yard
    Diabetes 2007 Sep; 56 (9): 2410-2413. https://doi.org/10.2337/db07-0128
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Online Letters to the Editor

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    Comment on: Hosagai et al. (2007) Adipose Tissue Hypoxia in Obesity and Its Impact on Adipocytokine Dysregulation: Diabetes 56:901–911
    Paul Trayhurn, Bohan Wang and I. Stuart Wood
    Diabetes 2007 Sep; 56 (9): e14. https://doi.org/10.2337/db07-0747
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    Comment on: Harmancey et al. (2007) Adrenomedullin Inhibits Adipogenesis Under Transcriptional Control of Insulin: Diabetes 56:553–563
    Kazuhiro Takahashi
    Diabetes 2007 Sep; 56 (9): e15. https://doi.org/10.2337/db07-0592
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    Comment on: Marchand and Polychronakos (2007) Evaluation of Polymorphic Splicing in the Mechanism of the Association of the Insulin Gene with Diabetes: Diabetes 56:709–713
    Santiago Rodriguez, Tom R. Gaunt, Igoř Vorechovský, Jana Kralovičová, Peter J. Wood and Ian N.M. Day
    Diabetes 2007 Sep; 56 (9): e16. https://doi.org/10.2337/db07-0805
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    Response to Comment on: Marchand and Polychronakos (2007) Evaluation of Polymorphic Splicing in the Mechanism of the Association of the Insulin Gene with Diabetes: Diabetes 56:709–713
    Luc Marchand and Constantin Polychronakos
    Diabetes 2007 Sep; 56 (9): e17. https://doi.org/10.2337/db07-0836
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September 2007, 56(9)
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