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Table of Contents

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October 01 2008; volume 57 issue 10

Perspectives in Diabetes

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    The “Perfect Storm” for Type 1 DiabetesThe Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity
    Outi Vaarala, Mark A. Atkinson and Josef Neu
    Diabetes 2008 Oct; 57 (10): 2555-2562. https://doi.org/10.2337/db08-0331
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Commentaries

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    Mary, Mary, Quite Contrary, How Do Your β-Cells Fail?
    Jack L. Leahy
    Diabetes 2008 Oct; 57 (10): 2563-2564. https://doi.org/10.2337/db08-0869
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    Vitamin D and Type 2 DiabetesAre We Ready for a Prevention Trial?
    Robert Scragg
    Diabetes 2008 Oct; 57 (10): 2565-2566. https://doi.org/10.2337/db08-0879
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    Role of MicroRNA in Pancreatic β-CellsWhere More Is Less
    Michael D. Walker
    Diabetes 2008 Oct; 57 (10): 2567-2568. https://doi.org/10.2337/db08-0934
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Metabolism

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    Metabolism-Independent Sugar Sensing in Central Orexin Neurons
    J. Antonio González, Lise T. Jensen, Lars Fugger and Denis Burdakov
    Diabetes 2008 Oct; 57 (10): 2569-2576. https://doi.org/10.2337/db08-0548
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    Brain Glucagon-Like Peptide-1 Regulates Arterial Blood Flow, Heart Rate, and Insulin Sensitivity
    Cendrine Cabou, Gérard Campistron, Nicolas Marsollier, Corinne Leloup, Celine Cruciani-Guglielmacci, Luc Pénicaud, Daniel J. Drucker, Christophe Magnan and Rémy Burcelin
    Diabetes 2008 Oct; 57 (10): 2577-2587. https://doi.org/10.2337/db08-0121
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    Cerebral Blood Flow and Cerebral Edema in Rats With Diabetic Ketoacidosis
    Natalie Yuen, Steven E. Anderson, Nicole Glaser, Daniel J. Tancredi and Martha E. O'Donnell
    Diabetes 2008 Oct; 57 (10): 2588-2594. https://doi.org/10.2337/db07-1410
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    Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects
    Sara M. Reyna, Sangeeta Ghosh, Puntip Tantiwong, C.S. Reddy Meka, Phyllis Eagan, Christopher P. Jenkinson, Eugenio Cersosimo, Ralph A. DeFronzo, Dawn K. Coletta, Apiradee Sriwijitkamol and Nicolas Musi
    Diabetes 2008 Oct; 57 (10): 2595-2602. https://doi.org/10.2337/db08-0038
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    Role of Central Nervous System Glucagon-Like Peptide-1 Receptors in Enteric Glucose Sensing
    Claude Knauf, Patrice D. Cani, Dong-Hoon Kim, Miguel A. Iglesias, Chantal Chabo, Aurélie Waget, André Colom, Sophie Rastrelli, Nathalie M. Delzenne, Daniel J. Drucker, Randy J. Seeley and Remy Burcelin
    Diabetes 2008 Oct; 57 (10): 2603-2612. https://doi.org/10.2337/db07-1788
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    Physical Activity and Insulin SensitivityThe RISC Study
    Beverley Balkau, Leila Mhamdi, Jean-Michel Oppert, John Nolan, Alain Golay, Francesca Porcellati, Markku Laakso and Ele Ferrannini
    Diabetes 2008 Oct; 57 (10): 2613-2618. https://doi.org/10.2337/db07-1605
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Signal Transduction

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    Baseline Serum 25-Hydroxy Vitamin D Is Predictive of Future Glycemic Status and Insulin ResistanceThe Medical Research Council Ely Prospective Study 1990–2000
    Nita G. Forouhi, Jian'an Luan, Andrew Cooper, Barbara J. Boucher and Nicholas J. Wareham
    Diabetes 2008 Oct; 57 (10): 2619-2625. https://doi.org/10.2337/db08-0593
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    Mechanism of Oxidative DNA Damage in DiabetesTuberin Inactivation and Downregulation of DNA Repair Enzyme 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine-DNA Glycosylase
    Simona Simone, Yves Gorin, Chakradhar Velagapudi, Hanna E. Abboud and Samy L. Habib
    Diabetes 2008 Oct; 57 (10): 2626-2636. https://doi.org/10.2337/db07-1579
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    Integrin-Associated Protein Association With Src Homology 2 Domain Containing Tyrosine Phosphatase Substrate 1 Regulates IGF-I Signaling In Vivo
    Laura A. Maile, Byron E. Capps, Emily C. Miller, Ariel W. Aday and David R. Clemmons
    Diabetes 2008 Oct; 57 (10): 2637-2643. https://doi.org/10.2337/db08-0326
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    Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle
    Katsutaro Morino, Susanne Neschen, Stefan Bilz, Saki Sono, Dimitrios Tsirigotis, Richard M. Reznick, Irene Moore, Yoshio Nagai, Varman Samuel, David Sebastian, Morris White, William Philbrick and Gerald I. Shulman
    Diabetes 2008 Oct; 57 (10): 2644-2651. https://doi.org/10.2337/db06-0454
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Obesity Studies

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    Impaired Glucose Tolerance and Insulin Resistance Are Associated With Increased Adipose 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Elevated Hepatic 5α-Reductase Activity
    Jeremy W. Tomlinson, Joanne Finney, Christopher Gay, Beverly A. Hughes, Susan V. Hughes and Paul M. Stewart
    Diabetes 2008 Oct; 57 (10): 2652-2660. https://doi.org/10.2337/db08-0495
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    Diurnal Variation of Human Sweet Taste Recognition Thresholds Is Correlated With Plasma Leptin Levels
    Yuki Nakamura, Keisuke Sanematsu, Rie Ohta, Shinya Shirosaki, Kiyoshi Koyano, Kazuaki Nonaka, Noriatsu Shigemura and Yuzo Ninomiya
    Diabetes 2008 Oct; 57 (10): 2661-2665. https://doi.org/10.2337/db07-1103
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Immunology and Transplantation

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    Simultaneous Islet and Kidney Transplantation in Seven Patients With Type 1 Diabetes and End-Stage Renal Disease Using a Glucocorticoid-Free Immunosuppressive Regimen With Alemtuzumab Induction
    Jianming Tan, Shunliang Yang, Jinquan Cai, Junqi Guo, Lianghu Huang, Zhixian Wu, Jin Chen and Lianming Liao
    Diabetes 2008 Oct; 57 (10): 2666-2671. https://doi.org/10.2337/db08-0358
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    CD28/CD154 Blockade Prevents Autoimmune Diabetes by Inducing Nondeletional Tolerance After Effector T-Cell Inhibition and Regulatory T-Cell Expansion
    Mark R. Rigby, Alison M. Trexler, Thomas C. Pearson and Christian P. Larsen
    Diabetes 2008 Oct; 57 (10): 2672-2683. https://doi.org/10.2337/db07-1712
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    Transforming Growth Factor-β Suppresses the Activation of CD8+ T-Cells When Naïve but Promotes Their Survival and Function Once Antigen Experienced A Two-Faced Impact on Autoimmunity
    Christophe M. Filippi, Amy E. Juedes, Janine E. Oldham, Ellie Ling, Lisa Togher, Yufeng Peng, Richard A. Flavell and Matthias G. von Herrath
    Diabetes 2008 Oct; 57 (10): 2684-2692. https://doi.org/10.2337/db08-0609
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    A Common Nonsynonymous Single Nucleotide Polymorphism in the SLC30A8 Gene Determines ZnT8 Autoantibody Specificity in Type 1 Diabetes
    Janet M. Wenzlau, Yu Liu, Liping Yu, Ong Moua, Kimberly T. Fowler, Sampathkumar Rangasamy, Jay Walters, George S. Eisenbarth, Howard W. Davidson and John C. Hutton
    Diabetes 2008 Oct; 57 (10): 2693-2697. https://doi.org/10.2337/db08-0522
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Islet Studies

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    Decreased Fetal Size Is Associated With β-Cell Hyperfunction in Early Life and Failure With Age
    Manu V. Chakravarthy, Yimin Zhu, Mitchell B. Wice, Trey Coleman, Kirk L. Pappan, Connie A. Marshall, Michael L. McDaniel and Clay F. Semenkovich
    Diabetes 2008 Oct; 57 (10): 2698-2707. https://doi.org/10.2337/db08-0404
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    miR-375 Targets 3′-Phosphoinositide–Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic β-Cells
    Abdelfattah El Ouaamari, Nadine Baroukh, Geert A. Martens, Patricia Lebrun, Daniel Pipeleers and Emmanuel van Obberghen
    Diabetes 2008 Oct; 57 (10): 2708-2717. https://doi.org/10.2337/db07-1614
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    Postnatal Expansion of the Pancreatic β-Cell Mass Is Dependent on Survivin
    Yuying Jiang, Wataru Nishimura, Deborah Devor-Henneman, Donna Kusewitt, Haijuan Wang, Michael P. Holloway, Takehiko Dohi, Edmond Sabo, Michael L. Robinson, Dario C. Altieri, Arun Sharma and Rachel A. Altura
    Diabetes 2008 Oct; 57 (10): 2718-2727. https://doi.org/10.2337/db08-0170
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    Alterations in MicroRNA Expression Contribute to Fatty Acid–Induced Pancreatic β-Cell Dysfunction
    Pascal Lovis, Elodie Roggli, D. Ross Laybutt, Sonia Gattesco, Jiang-Yan Yang, Christian Widmann, Amar Abderrahmani and Romano Regazzi
    Diabetes 2008 Oct; 57 (10): 2728-2736. https://doi.org/10.2337/db07-1252
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    Spontaneous Diabetes in Hemizygous Human Amylin Transgenic Mice That Developed Neither Islet Amyloid nor Peripheral Insulin Resistance
    Winifred P.S. Wong, David W. Scott, Chia-Lin Chuang, Shaoping Zhang, Hong Liu, Athena Ferreira, Etuate L. Saafi, Yee Soon Choong and Garth J.S. Cooper
    Diabetes 2008 Oct; 57 (10): 2737-2744. https://doi.org/10.2337/db06-1755
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    Hepatocyte Growth Factor Enhances Engraftment and Function of Nonhuman Primate Islets
    Nathalie M. Fiaschi-Taesch, Dora M. Berman, Brian M. Sicari, Karen K. Takane, Adolfo Garcia-Ocaña, Camillo Ricordi, Norma S. Kenyon and Andrew F. Stewart
    Diabetes 2008 Oct; 57 (10): 2745-2754. https://doi.org/10.2337/db07-1085
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    Mouse Pancreatic Endocrine Cell Transcriptome Defined in the Embryonic Ngn3-Null Mouse
    Kirstine Juhl, Suparna A. Sarkar, Randall Wong, Jan Jensen and John C. Hutton
    Diabetes 2008 Oct; 57 (10): 2755-2761. https://doi.org/10.2337/db07-1126
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Pathophysiology

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    Plasma Fetuin-A Levels and the Risk of Type 2 Diabetes
    Norbert Stefan, Andreas Fritsche, Cornelia Weikert, Heiner Boeing, Hans-Georg Joost, Hans-Ulrich Häring and Matthias B. Schulze
    Diabetes 2008 Oct; 57 (10): 2762-2767. https://doi.org/10.2337/db08-0538
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    Distinct Monocyte Gene-Expression Profiles in Autoimmune Diabetes
    Roos C. Padmos, Nanette C. Schloot, Huriya Beyan, Cindy Ruwhof, Frank J.T. Staal, Dick de Ridder, Henk-Jan Aanstoot, Wai Kwan Lam-Tse, Harm de Wit, Christian de Herder, Roos C. Drexhage, Barbara Menart, R. David Leslie, Hemmo A. Drexhage and the LADA Consortium
    Diabetes 2008 Oct; 57 (10): 2768-2773. https://doi.org/10.2337/db08-0496
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Complications

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    Neuronatin: A New Inflammation Gene Expressed on the Aortic Endothelium of Diabetic Mice
    Nino Mzhavia, Shuiqing Yu, Shota Ikeda, Tehua T. Chu, Ira Goldberg and Hayes M. Dansky
    Diabetes 2008 Oct; 57 (10): 2774-2783. https://doi.org/10.2337/db07-1746
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    Potent Inhibition of Cicatricial Contraction in Proliferative Vitreoretinal Diseases by Statins
    Shuhei Kawahara, Yasuaki Hata, Takeshi Kita, Ryoichi Arita, Muneki Miura, Shintaro Nakao, Yasutaka Mochizuki, Hiroshi Enaida, Tadahisa Kagimoto, Yoshinobu Goto, Ali Hafezi-Moghadam and Tatsuro Ishibashi
    Diabetes 2008 Oct; 57 (10): 2784-2793. https://doi.org/10.2337/db08-0302
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    Correction of HDL Dysfunction in Individuals With Diabetes and the Haptoglobin 2-2 Genotype
    Rabea Asleh, Shany Blum, Shiri Kalet-Litman, Jonia Alshiek, Rachel Miller-Lotan, Roy Asaf, Wasseem Rock, Michael Aviram, Uzi Milman, Chen Shapira, Zaid Abassi and Andrew P. Levy
    Diabetes 2008 Oct; 57 (10): 2794-2800. https://doi.org/10.2337/db08-0450
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    Sulfasalazine Blocks the Development of Tactile Allodynia in Diabetic Rats
    Liliana N. Berti-Mattera, Timothy S. Kern, Ruth E. Siegel, Ina Nemet and Rochanda Mitchell
    Diabetes 2008 Oct; 57 (10): 2801-2808. https://doi.org/10.2337/db07-1274
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    Activation of NF-E2–Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease
    Mingzhan Xue, Qingwen Qian, Antonysunil Adaikalakoteswari, Naila Rabbani, Roya Babaei-Jadidi and Paul J. Thornalley
    Diabetes 2008 Oct; 57 (10): 2809-2817. https://doi.org/10.2337/db06-1003
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    Impaired Collateral Recruitment and Outward Remodeling in Experimental Diabetes
    Jolanda M. van Golde, Matthijs S. Ruiter, Nicolaas C. Schaper, Stefan Vöö, Johannes Waltenberger, Walter H. Backes, Mark J. Post and Maya S. Huijberts
    Diabetes 2008 Oct; 57 (10): 2818-2823. https://doi.org/10.2337/db08-0229
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    Inducible Overexpression of sFlt-1 in Podocytes Ameliorates Glomerulopathy in Diabetic Mice
    Ching-Hsin Ku, Kathryn E. White, Alessandra Dei Cas, Anthea Hayward, Zoe Webster, Rudy Bilous, Sally Marshall, Giancarlo Viberti and Luigi Gnudi
    Diabetes 2008 Oct; 57 (10): 2824-2833. https://doi.org/10.2337/db08-0647
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Genetics

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    Common Variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE Genes Are Associated With Type 2 Diabetes and Impaired Fasting Glucose in a Chinese Han Population
    Ying Wu, Huaixing Li, Ruth J.F. Loos, Zhijie Yu, Xingwang Ye, Lihua Chen, An Pan, Frank B. Hu and Xu Lin
    Diabetes 2008 Oct; 57 (10): 2834-2842. https://doi.org/10.2337/db08-0047
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    G/T Substitution in Intron 1 of the UNC13B Gene Is Associated With Increased Risk of Nephropathy in Patients With Type 1 Diabetes
    David-Alexandre Trégouet, Per-Henrik Groop, Steven McGinn, Carol Forsblom, Samy Hadjadj, Michel Marre, Hans-Henrik Parving, Lise Tarnow, Ralph Telgmann, Tiphaine Godefroy, Viviane Nicaud, Rachel Rousseau, Maikki Parkkonen, Anna Hoverfält, Ivo Gut, Simon Heath, Fumihiko Matsuda, Roger Cox, Gbenga Kazeem, Martin Farrall, Dominique Gauguier, Stefan-Martin Brand-Herrmann, François Cambien, Mark Lathrop and Nathalie Vionnet
    Diabetes 2008 Oct; 57 (10): 2843-2850. https://doi.org/10.2337/db08-0073
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    FTO Variants Are Associated With Obesity in the Chinese and Malay Populations in Singapore
    Jonathan T. Tan, Rajkumar Dorajoo, Mark Seielstad, Xue Ling Sim, Rick Twee-Hee Ong, Kee Seng Chia, Tien Yin Wong, Seang Mei Saw, Suok Kai Chew, Tin Aung and E-Shyong Tai
    Diabetes 2008 Oct; 57 (10): 2851-2857. https://doi.org/10.2337/db08-0214
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    A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3
    Patrick Concannon, Suna Onengut-Gumuscu, John A. Todd, Deborah J. Smyth, Flemming Pociot, Regine Bergholdt, Beena Akolkar, Henry A. Erlich, Joan E. Hilner, Cécile Julier, Grant Morahan, Jørn Nerup, Concepcion R. Nierras, Wei-Min Chen, Stephen S. Rich and the Type 1 Diabetes Genetics Consortium
    Diabetes 2008 Oct; 57 (10): 2858-2861. https://doi.org/10.2337/db08-0753
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October 2008, 57(10)
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  • Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis
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