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Original Article

Differences in Baseline Lymphocyte Counts and Autoreactivity Are Associated With Differences in Outcome of Islet Cell Transplantation in Type 1 Diabetic Patients

  1. Robert Hilbrands1,2,
  2. Volkert A.L. Huurman2,3,
  3. Pieter Gillard1,2,4,
  4. Jurjen H.L. Velthuis2,3,
  5. Marc De Waele1,
  6. Chantal Mathieu2,4,
  7. Leonard Kaufman5,
  8. Miriam Pipeleers-Marichal1,
  9. Zhidong Ling1,2,
  10. Babak Movahedi1,2,
  11. Daniel Jacobs-Tulleneers-Thevissen1,2,
  12. Diethard Monbaliu6,
  13. Dirk Ysebaert7,
  14. Frans K. Gorus1,2,
  15. Bart O. Roep2,3,
  16. Daniel G. Pipeleers1,2 and
  17. Bart Keymeulen1,2
  1. 1Diabetes Research Center and Universitair Ziekenhuis Brussels, Brussels Free University-Vrije Universiteit Brussel (VUB), Brussels, Belgium;
  2. 2Juvenile Diabetes Research Foundation Center for β-Cell Therapy in Diabetes, Brussels, Belgium;
  3. 3Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands;
  4. 4Department of Endocrinology, Universitair Ziekenhuis Gasthuisberg, Catholic University of Leuven, Leuven, Belgium;
  5. 5Department of Biostatistics, Brussels Free University-VUB, Brussels, Belgium;
  6. 6Department of Surgery, Universitair Ziekenhuis Gasthuisberg, Catholic University of Leuven, Leuven, Belgium;
  7. 7Department of Surgery, Universitair Ziekenhuis Antwerpen, University of Antwerp, Antwerp, Belgium.
  1. Corresponding author: Bart Keymeulen, bart.keymeulen{at}uzbrussel.be.
  1. R.H. and V.A.L.H. contributed equally to this article.

Diabetes 2009 Oct; 58(10): 2267-2276. https://doi.org/10.2337/db09-0160
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October 2009, 58(10)
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Differences in Baseline Lymphocyte Counts and Autoreactivity Are Associated With Differences in Outcome of Islet Cell Transplantation in Type 1 Diabetic Patients
Robert Hilbrands, Volkert A.L. Huurman, Pieter Gillard, Jurjen H.L. Velthuis, Marc De Waele, Chantal Mathieu, Leonard Kaufman, Miriam Pipeleers-Marichal, Zhidong Ling, Babak Movahedi, Daniel Jacobs-Tulleneers-Thevissen, Diethard Monbaliu, Dirk Ysebaert, Frans K. Gorus, Bart O. Roep, Daniel G. Pipeleers, Bart Keymeulen
Diabetes Oct 2009, 58 (10) 2267-2276; DOI: 10.2337/db09-0160

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Differences in Baseline Lymphocyte Counts and Autoreactivity Are Associated With Differences in Outcome of Islet Cell Transplantation in Type 1 Diabetic Patients
Robert Hilbrands, Volkert A.L. Huurman, Pieter Gillard, Jurjen H.L. Velthuis, Marc De Waele, Chantal Mathieu, Leonard Kaufman, Miriam Pipeleers-Marichal, Zhidong Ling, Babak Movahedi, Daniel Jacobs-Tulleneers-Thevissen, Diethard Monbaliu, Dirk Ysebaert, Frans K. Gorus, Bart O. Roep, Daniel G. Pipeleers, Bart Keymeulen
Diabetes Oct 2009, 58 (10) 2267-2276; DOI: 10.2337/db09-0160
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Original Article

  • An Update on the Molecular Actions of Fenofibrate and Its Clinical Effects on Diabetic Retinopathy and Other Microvascular End Points in Patients With Diabetes
  • Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development
  • Cbl-b Is a Critical Regulator of Macrophage Activation Associated With Obesity-Induced Insulin Resistance in Mice
Show more Original Article

Immunology and Transplantation

  • InsB9-23 Gene Transfer to Hepatocyte-Based Combined Therapy Abrogates Recurrence of Type 1 Diabetes After Islet Transplantation
  • Peptides Derived From Insulin Granule Proteins Are Targeted by CD8+ T Cells Across MHC Class I Restrictions in Humans and NOD Mice
  • Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms
Show more Immunology and Transplantation

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