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Original Article

Activation of Insulin-Reactive CD8 T-Cells for Development of Autoimmune Diabetes

  1. F. Susan Wong1,
  2. Lai Khai Siew1,
  3. Gwen Scott1,
  4. Ian J. Thomas1,
  5. Stephen Chapman1,
  6. Christophe Viret2 and
  7. Li Wen3
  1. 1Department of Cellular and Molecular Medicine, University of Bristol, Bristol, U.K.; the
  2. 2Centre de Physiopathologie de Toulouse Purpan, INSERM, U563-BAT A CHU Purpan, Toulouse, France; and the
  3. 3Section of Endocrinology, Yale University School of Medicine, New Haven, Connecticut.
  1. Corresponding author: Susan Wong, susan.wong{at}bristol.ac.uk.
Diabetes 2009 May; 58(5): 1156-1164. https://doi.org/10.2337/db08-0800
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May 2009, 58(5)
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Activation of Insulin-Reactive CD8 T-Cells for Development of Autoimmune Diabetes
F. Susan Wong, Lai Khai Siew, Gwen Scott, Ian J. Thomas, Stephen Chapman, Christophe Viret, Li Wen
Diabetes May 2009, 58 (5) 1156-1164; DOI: 10.2337/db08-0800

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Activation of Insulin-Reactive CD8 T-Cells for Development of Autoimmune Diabetes
F. Susan Wong, Lai Khai Siew, Gwen Scott, Ian J. Thomas, Stephen Chapman, Christophe Viret, Li Wen
Diabetes May 2009, 58 (5) 1156-1164; DOI: 10.2337/db08-0800
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  • Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development
  • Cbl-b Is a Critical Regulator of Macrophage Activation Associated With Obesity-Induced Insulin Resistance in Mice
Show more Original Article

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  • Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice
  • Differentiating MHC-Dependent and -Independent Mechanisms of Lymph Node Stromal Cell Regulation of Proinsulin-Specific CD8+ T Cells in Type 1 Diabetes
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