Short-Term Exercise Training Does Not Stimulate Skeletal Muscle ATP Synthesis in Relatives of Humans With Type 2 Diabetes

Gertrud Kacerovsky-Bielesz; Marek Chmelik; Charlotte Ling; Rochus Pokan; Julia Szendroedi; Michaela Farukuoye; Michaela Kacerovsky; Albrecht I. Schmid; Stephan Gruber; Michael Wolzt; Ewald Moser; Giovanni Pacini; Gerhard Smekal; Leif Groop; Michael Roden

doi:10.2337/db08-1240

Original Article

Short-Term Exercise Training Does Not Stimulate Skeletal Muscle ATP Synthesis in Relatives of Humans With Type 2 Diabetes

Gertrud Kacerovsky-Bielesz¹,²,
Marek Chmelik²,³,
Charlotte Ling⁴,
Rochus Pokan⁵,
Julia Szendroedi¹,²,
Michaela Farukuoye²,
Michaela Kacerovsky²,
Albrecht I. Schmid²,³,
Stephan Gruber³,
Michael Wolzt⁶,
Ewald Moser³,
Giovanni Pacini⁷,
Gerhard Smekal⁵,
Leif Groop⁴ and
Michael Roden¹,²,⁸

¹Medical Department, Hanusch Hospital, Vienna, Austria;
²Karl-Landsteiner Institute for Endocrinology and Metabolism, Vienna, Austria;
³MR Center of Excellence, Medical University of Vienna, Vienna, Austria;
⁴Department of Clinical Sciences, Lund University, Malmö, Sweden;
⁵Department of Sports and Exercise Physiology, University of Vienna, Vienna, Austria;
⁶Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;
⁷Metabolic Unit, Institute of Biomedical Engineering, Consiglio Nazionale delle Ricerche, Padua, Italy;
⁸Institute for Clinical Diabetology, German Diabetes Center-Leibniz Center for Diabetes Research, Department of Medicine/Metabolic Diseases, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Corresponding author: Michael Roden, michael.roden{at}ddz.uni-duesseldorf.de.

Diabetes 2009 Jun; 58(6): 1333-1341. https://doi.org/10.2337/db08-1240

Article Information

vol. 58 no. 6 1333-1341

DOI

https://doi.org/10.2337/db08-1240

PubMed

19265027

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

September 6, 2008
February 27, 2009
Published in print May 21, 2009.
Published online ahead of print March 5, 2009.

Article Versions

Previous version (March 5, 2009 - 11:59).
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© 2009 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

Author Information

Gertrud Kacerovsky-Bielesz¹,²,
Marek Chmelik²,³,
Charlotte Ling⁴,
Rochus Pokan⁵,
Julia Szendroedi¹,²,
Michaela Farukuoye²,
Michaela Kacerovsky²,
Albrecht I. Schmid²,³,
Stephan Gruber³,
Michael Wolzt⁶,
Ewald Moser³,
Giovanni Pacini⁷,
Gerhard Smekal⁵,
Leif Groop⁴ and
Michael Roden¹,²,⁸

¹Medical Department, Hanusch Hospital, Vienna, Austria;
²Karl-Landsteiner Institute for Endocrinology and Metabolism, Vienna, Austria;
³MR Center of Excellence, Medical University of Vienna, Vienna, Austria;
⁴Department of Clinical Sciences, Lund University, Malmö, Sweden;
⁵Department of Sports and Exercise Physiology, University of Vienna, Vienna, Austria;
⁶Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria;
⁷Metabolic Unit, Institute of Biomedical Engineering, Consiglio Nazionale delle Ricerche, Padua, Italy;
⁸Institute for Clinical Diabetology, German Diabetes Center-Leibniz Center for Diabetes Research, Department of Medicine/Metabolic Diseases, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Corresponding author: Michael Roden, michael.roden{at}ddz.uni-duesseldorf.de.

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