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Islet Studies

Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study

  1. Hillary A. Keenan1,2,
  2. Jennifer K. Sun1,3,4,
  3. Jared Levine1,2,
  4. Alessandro Doria1,2,
  5. Lloyd P. Aiello1,3,4,
  6. George Eisenbarth5,
  7. Susan Bonner-Weir1,2 and
  8. George L. King1,2
  1. 1Research Division, Joslin Diabetes Center, Boston, Massachusetts;
  2. 2Department of Medicine, Harvard Medical School, Boston, Massachusetts;
  3. 3Beetham Eye Institute, Joslin Diabetes Center, Boston, Massachusetts;
  4. 4Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts;
  5. 5Barbara Davis Center for Childhood Diabetes, Denver, Colorado.
  1. Corresponding author: George L. King, George.King{at}joslin.harvard.edu.
Diabetes 2010 Nov; 59(11): 2846-2853. https://doi.org/10.2337/db10-0676
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Article Information

vol. 59 no. 11 2846-2853
DOI 
https://doi.org/10.2337/db10-0676
PubMed 
20699420

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • Received May 12, 2010
  • Accepted July 30, 2010
  • Published in print October 27, 2010.
  • Published online ahead of print August 10, 2010.

Article Versions

  • Previous version (August 10, 2010 - 09:53).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

Author Information

  1. Hillary A. Keenan1,2,
  2. Jennifer K. Sun1,3,4,
  3. Jared Levine1,2,
  4. Alessandro Doria1,2,
  5. Lloyd P. Aiello1,3,4,
  6. George Eisenbarth5,
  7. Susan Bonner-Weir1,2 and
  8. George L. King1,2
  1. 1Research Division, Joslin Diabetes Center, Boston, Massachusetts;
  2. 2Department of Medicine, Harvard Medical School, Boston, Massachusetts;
  3. 3Beetham Eye Institute, Joslin Diabetes Center, Boston, Massachusetts;
  4. 4Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts;
  5. 5Barbara Davis Center for Childhood Diabetes, Denver, Colorado.
  1. Corresponding author: George L. King, George.King{at}joslin.harvard.edu.
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Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study
Hillary A. Keenan, Jennifer K. Sun, Jared Levine, Alessandro Doria, Lloyd P. Aiello, George Eisenbarth, Susan Bonner-Weir, George L. King
Diabetes Nov 2010, 59 (11) 2846-2853; DOI: 10.2337/db10-0676

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Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study
Hillary A. Keenan, Jennifer K. Sun, Jared Levine, Alessandro Doria, Lloyd P. Aiello, George Eisenbarth, Susan Bonner-Weir, George L. King
Diabetes Nov 2010, 59 (11) 2846-2853; DOI: 10.2337/db10-0676
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  • Loss of Furin in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction
  • SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients
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