AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

Jee-Hyun Um; Sung-Jun Park; Hyeog Kang; Shutong Yang; Marc Foretz; Michael W. McBurney; Myung K. Kim; Benoit Viollet; Jay H. Chung

doi:10.2337/db09-0482

Original Article

AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

Jee-Hyun Um¹,
Sung-Jun Park¹,
Hyeog Kang¹,
Shutong Yang¹,
Marc Foretz²,³,
Michael W. McBurney⁴,
Myung K. Kim¹,
Benoit Viollet²,³ and
Jay H. Chung¹

¹Laboratory of Biochemical Genetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland;
²Institut Cochin, Université Paris Descartes, Centre National de la Recherche Scientifique (UMR 8104), Paris, France;
³National de la Santé et de la Recherche Médicale, Paris, France;
⁴Center for Cancer Therapeutics, Ottawa Health Research Institute, Ottawa, Ontario, Canada.

Corresponding author: Jay H. Chung, chungj{at}nhlbi.nih.gov.

J.-H.U. and S.-J.P. contributed equally to this article.

Diabetes 2010 Mar; 59(3): 554-563. https://doi.org/10.2337/db09-0482

Article Information

vol. 59 no. 3 554-563

DOI

https://doi.org/10.2337/db09-0482

PubMed

19934007

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

Received April 1, 2009
Accepted October 30, 2009
Published in print February 26, 2010.
Published online ahead of print November 23, 2009.

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Previous version (November 23, 2009 - 13:28).
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© 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

Author Information

Jee-Hyun Um¹,
Sung-Jun Park¹,
Hyeog Kang¹,
Shutong Yang¹,
Marc Foretz²,³,
Michael W. McBurney⁴,
Myung K. Kim¹,
Benoit Viollet²,³ and
Jay H. Chung¹

¹Laboratory of Biochemical Genetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland;
²Institut Cochin, Université Paris Descartes, Centre National de la Recherche Scientifique (UMR 8104), Paris, France;
³National de la Santé et de la Recherche Médicale, Paris, France;
⁴Center for Cancer Therapeutics, Ottawa Health Research Institute, Ottawa, Ontario, Canada.

Corresponding author: Jay H. Chung, chungj{at}nhlbi.nih.gov.

J.-H.U. and S.-J.P. contributed equally to this article.

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