Skip to main content
  • More from ADA
    • Diabetes Care
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care in Diabetes
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care
  • Subscribe
  • Log in
  • My Cart
  • Follow ada on Twitter
  • RSS
  • Visit ada on Facebook
Diabetes

Advanced Search

Main menu

  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • ADA Scientific Sessions Abstracts
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • ADA Scientific Sessions Abstracts
    • Diabetes COVID-19 Article Collection
    • Diabetes Symposium 2020
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Submit Cover Art
    • ADA Journal Policies
    • Instructions for Authors
    • ADA Peer Review
  • More from ADA
    • Diabetes Care
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care in Diabetes
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care

User menu

  • Subscribe
  • Log in
  • My Cart

Search

  • Advanced search
Diabetes
  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • ADA Scientific Sessions Abstracts
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • ADA Scientific Sessions Abstracts
    • Diabetes COVID-19 Article Collection
    • Diabetes Symposium 2020
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Submit Cover Art
    • ADA Journal Policies
    • Instructions for Authors
    • ADA Peer Review
Original Article

Hyperglycemia Impairs Proteasome Function by Methylglyoxal

  1. Markus A. Queisser1,2,
  2. Dachun Yao2,
  3. Sven Geisler1,
  4. Hans-Peter Hammes3,
  5. Günter Lochnit1,
  6. Erwin D. Schleicher4,5,
  7. Michael Brownlee2 and
  8. Klaus T. Preissner1
  1. 1School of Medicine, Institute of Biochemistry, Justus-Liebig-University, Giessen, Germany;
  2. 2Diabetes Center, Albert Einstein College of Medicine, New York, New York;
  3. 3Department of Endocrinology, University of Heidelberg, Mannheim, Germany;
  4. 4Department of Medicine IV, Eberhard-Karls-University, Tübingen, Germany;
  5. 5Department of Neurology, Eberhard-Karls-University, Tübingen, Germany.
  1. Corresponding author: Klaus T. Preissner, klaus.t.preissner{at}biochemie.med.uni-giessen.de.
  1. M.A.Q., D.Y., M.B., and K.T.P. contributed equally to this work.

Diabetes 2010 Mar; 59(3): 670-678. https://doi.org/10.2337/db08-1565
PreviousNext
  • Article
  • Figures & Tables
  • Info & Metrics
  • PDF
Loading

Article Information

vol. 59 no. 3 670-678
DOI 
https://doi.org/10.2337/db08-1565
PubMed 
20009088

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • Received November 10, 2008
  • Accepted December 3, 2009
  • Published in print February 26, 2010.
  • Published online ahead of print December 15, 2009.

Article Versions

  • Previous version (December 15, 2009 - 14:06).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

Author Information

  1. Markus A. Queisser1,2,
  2. Dachun Yao2,
  3. Sven Geisler1,
  4. Hans-Peter Hammes3,
  5. Günter Lochnit1,
  6. Erwin D. Schleicher4,5,
  7. Michael Brownlee2 and
  8. Klaus T. Preissner1
  1. 1School of Medicine, Institute of Biochemistry, Justus-Liebig-University, Giessen, Germany;
  2. 2Diabetes Center, Albert Einstein College of Medicine, New York, New York;
  3. 3Department of Endocrinology, University of Heidelberg, Mannheim, Germany;
  4. 4Department of Medicine IV, Eberhard-Karls-University, Tübingen, Germany;
  5. 5Department of Neurology, Eberhard-Karls-University, Tübingen, Germany.
  1. Corresponding author: Klaus T. Preissner, klaus.t.preissner{at}biochemie.med.uni-giessen.de.
  1. M.A.Q., D.Y., M.B., and K.T.P. contributed equally to this work.

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: December 2009 to February 2021

Rendering graph...
AbstractFullPdf
Dec 2009332062
Jan 2010233083
Feb 2010274466
Mar 2010135147103
Apr 20102993650
May 20101932528
Jun 201013517831
Jul 20108813924
Aug 20108812424
Sep 2010859223
Oct 20107117819
Nov 20108811517
Dec 20104610714
Jan 20118411023
Feb 20117820720
Mar 20111023551
Apr 2011813333
May 2011553130
Jun 2011532826
Jul 2011471834
Aug 2011683543
Sep 2011622441
Oct 2011523023
Nov 2011542031
Dec 2011621917
Jan 2012694431
Feb 2012542720
Mar 2012634233
Apr 2012502219
May 2012472327
Jun 2012322524
Jul 2012402736
Aug 2012482322
Sep 2012432913
Oct 2012362219
Nov 2012581718
Dec 2012462716
Jan 2013392613
Feb 2013535228
Mar 2013541916
Apr 2013512218
May 201342277
Jun 2013291410
Jul 2013251514
Aug 201326109
Sep 2013451410
Oct 2013373011
Nov 2013232414
Dec 2013211313
Jan 2014262917
Feb 2014312116
Mar 2014343526
Apr 201430447
May 2014474224
Jun 201430199
Jul 2014432311
Aug 2014312317
Sep 20142385
Oct 2014251917
Nov 2014471512
Dec 201436149
Jan 2015241415
Feb 201522698
Mar 2015281912
Apr 2015182718
May 2015141210
Jun 2015141813
Jul 2015201211
Aug 2015242010
Sep 2015383916
Oct 201515199
Nov 2015361311
Dec 201534216
Jan 2016321913
Feb 2016282112
Mar 2016784316
Apr 201628106
May 2016183220
Jun 2016101815
Jul 201663729
Aug 201685231
Sep 201674112
Oct 2016247730
Nov 201645513
Dec 20168348
Jan 20172467
Feb 20178299
Mar 20172327
Apr 20172227
May 20174336
Jun 20175276
Jul 20170475
Aug 20173269
Sep 201712012
Oct 20171358
Nov 20175367
Dec 20176204
Jan 20182408
Feb 20180274
Mar 201844110
Apr 20180378
May 20181475
Jun 20182356
Jul 201842615
Aug 20180203
Sep 201843110
Oct 201844011
Nov 20184516
Dec 201855216
Jan 20195176
Feb 201992910
Mar 201972914
Apr 201993314
May 201943712
Jun 2019112422
Jul 2019142818
Aug 20196178
Sep 20199745
Oct 201941510
Nov 201982313
Dec 20194227
Jan 202061618
Feb 20204108
Mar 20207167
Apr 20202105
May 202083922
Jun 20206148
Jul 20201248
Aug 20202157
Sep 202071613
Oct 20203206
Nov 202093620
Dec 20207239
Jan 202142113
Feb 2021095

PreviousNext
Back to top

In this Issue

March 2010, 59(3)
  • Table of Contents
  • Index by Author
Sign up to receive current issue alerts
View Selected Citations (0)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word about Diabetes.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Hyperglycemia Impairs Proteasome Function by Methylglyoxal
(Your Name) has forwarded a page to you from Diabetes
(Your Name) thought you would like to see this page from the Diabetes web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Hyperglycemia Impairs Proteasome Function by Methylglyoxal
Markus A. Queisser, Dachun Yao, Sven Geisler, Hans-Peter Hammes, Günter Lochnit, Erwin D. Schleicher, Michael Brownlee, Klaus T. Preissner
Diabetes Mar 2010, 59 (3) 670-678; DOI: 10.2337/db08-1565

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Add to Selected Citations
Share

Hyperglycemia Impairs Proteasome Function by Methylglyoxal
Markus A. Queisser, Dachun Yao, Sven Geisler, Hans-Peter Hammes, Günter Lochnit, Erwin D. Schleicher, Michael Brownlee, Klaus T. Preissner
Diabetes Mar 2010, 59 (3) 670-678; DOI: 10.2337/db08-1565
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • RESEARCH DESIGN AND METHODS
    • RESULTS
    • DISCUSSION
    • ACKNOWLEDGMENTS
    • Footnotes
    • REFERENCES
  • Figures & Tables
  • Info & Metrics
  • PDF

Related Articles

Cited By...

More in this TOC Section

Original Article

  • An Update on the Molecular Actions of Fenofibrate and Its Clinical Effects on Diabetic Retinopathy and Other Microvascular End Points in Patients With Diabetes
  • Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development
  • Cbl-b Is a Critical Regulator of Macrophage Activation Associated With Obesity-Induced Insulin Resistance in Mice
Show more Original Article

Pathophysiology

  • Podocyte EGFR Inhibits Autophagy Through Upregulation of Rubicon in Type 2 Diabetic Nephropathy
  • A High-Fat Diet Attenuates AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo
  • Multinucleated Giant Cells in Adipose Tissue Are Specialized in Adipocyte Degradation
Show more Pathophysiology

Similar Articles

Navigate

  • Current Issue
  • Online Ahead of Print
  • Scientific Sessions Abstracts
  • Collections
  • Archives
  • Submit
  • Subscribe
  • Email Alerts
  • RSS Feeds

More Information

  • About the Journal
  • Instructions for Authors
  • Journal Policies
  • Reprints and Permissions
  • Advertising
  • Privacy Policy: ADA Journals
  • Copyright Notice/Public Access Policy
  • Contact Us

Other ADA Resources

  • Diabetes Care
  • Clinical Diabetes
  • Diabetes Spectrum
  • Scientific Sessions Abstracts
  • Standards of Medical Care in Diabetes
  • BMJ Open - Diabetes Research & Care
  • Professional Books
  • Diabetes Forecast

 

  • DiabetesJournals.org
  • Diabetes Core Update
  • ADA's DiabetesPro
  • ADA Member Directory
  • Diabetes.org

© 2021 by the American Diabetes Association. Diabetes Print ISSN: 0012-1797, Online ISSN: 1939-327X.