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Table of Contents

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August 01 2010; volume 59 issue 8

Perspectives in Diabetes

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    Are Individuals With Diabetes Seeing Better?A Long-Term Epidemiological Perspective
    Ronald Klein and Barbara E.K. Klein
    Diabetes 2010 Aug; 59 (8): 1853-1860. https://doi.org/10.2337/db09-1904
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Commentaries

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    β-Cells Step Up in Controlling the Autoimmune Response
    Paolo Fiorina
    Diabetes 2010 Aug; 59 (8): 1861-1864. https://doi.org/10.2337/db10-0662
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    Getting a Notch Closer to Understanding Diabetic Kidney Disease
    Seon-Ho Ahn and Katalin Susztak
    Diabetes 2010 Aug; 59 (8): 1865-1867. https://doi.org/10.2337/db10-0077
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    Translating “Nondiabetic” A1C Levels to Clinical PracticeThe Art of Medicine
    William T. Cefalu
    Diabetes 2010 Aug; 59 (8): 1868-1869. https://doi.org/10.2337/db10-0800
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Metabolism

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    The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes
    Pontus Boström, Linda Andersson, Birgitte Vind, Liliana Håversen, Mikael Rutberg, Ylva Wickström, Erik Larsson, Per-Anders Jansson, Maria K. Svensson, Richard Brånemark, Charlotte Ling, Henning Beck-Nielsen, Jan Borén, Kurt Højlund and Sven-Olof Olofsson
    Diabetes 2010 Aug; 59 (8): 1870-1878. https://doi.org/10.2337/db09-1503
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    Atrogin-1 Affects Muscle Protein Synthesis and Degradation When Energy Metabolism Is Impaired by the Antidiabetes Drug Berberine
    Huiling Wang, Dajun Liu, Peirang Cao, Stewart Lecker and Zhaoyong Hu
    Diabetes 2010 Aug; 59 (8): 1879-1889. https://doi.org/10.2337/db10-0207
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    Leptin Directly Depolarizes Preproglucagon Neurons in the Nucleus Tractus SolitariusElectrical Properties of Glucagon-Like Peptide 1 Neurons
    Kazunari Hisadome, Frank Reimann, Fiona M. Gribble and Stefan Trapp
    Diabetes 2010 Aug; 59 (8): 1890-1898. https://doi.org/10.2337/db10-0128
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    Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women
    Marleen Kars, Ling Yang, Margaret F. Gregor, B. Selma Mohammed, Terri A. Pietka, Brian N. Finck, Bruce W. Patterson, Jay D. Horton, Bettina Mittendorfer, Gökhan S. Hotamisligil and Samuel Klein
    Diabetes 2010 Aug; 59 (8): 1899-1905. https://doi.org/10.2337/db10-0308
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Signal Transduction

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    T-Cell Protein Tyrosine Phosphatase Attenuates STAT3 and Insulin Signaling in the Liver to Regulate Gluconeogenesis
    Atsushi Fukushima, Kim Loh, Sandra Galic, Barbara Fam, Ben Shields, Florian Wiede, Michel L. Tremblay, Matthew J. Watt, Sofianos Andrikopoulos and Tony Tiganis
    Diabetes 2010 Aug; 59 (8): 1906-1914. https://doi.org/10.2337/db09-1365
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    Modulation of Notch-1 Signaling Alleviates Vascular Endothelial Growth Factor–Mediated Diabetic Nephropathy
    Chun-Liang Lin, Feng-Sheng Wang, Yen-Chen Hsu, Cheng-Nan Chen, Min-Jen Tseng, Moin A. Saleem, Pey-Jium Chang and Jeng-Yi Wang
    Diabetes 2010 Aug; 59 (8): 1915-1925. https://doi.org/10.2337/db09-0663
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Islet Studies

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    Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6
    Nathalie M. Fiaschi-Taesch, Fatimah Salim, Jeffrey Kleinberger, Ronnie Troxell, Irene Cozar-Castellano, Karen Selk, Edward Cherok, Karen K. Takane, Donald K. Scott and Andrew F. Stewart
    Diabetes 2010 Aug; 59 (8): 1926-1936. https://doi.org/10.2337/db09-1776
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    PERK (EIF2AK3) Regulates Proinsulin Trafficking and Quality Control in the Secretory Pathway
    Sounak Gupta, Barbara McGrath and Douglas R. Cavener
    Diabetes 2010 Aug; 59 (8): 1937-1947. https://doi.org/10.2337/db09-1064
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    Mesenchymal Bone Morphogenetic Protein Signaling Is Required for Normal Pancreas Development
    Jonas Ahnfelt-Rønne, Philippe Ravassard, Corinne Pardanaud-Glavieux, Raphaél Scharfmann and Palle Serup
    Diabetes 2010 Aug; 59 (8): 1948-1956. https://doi.org/10.2337/db09-1010
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    Increased β-Cell Mass by Islet Transplantation and PLAG1 Overexpression Causes Hyperinsulinemic Normoglycemia and Hepatic Insulin Resistance in Mice
    Jeroen Declercq, Anujith Kumar, Janna A. Van Diepen, Irene O.C.M. Vroegrijk, Conny Gysemans, Caterina Di Pietro, Peter J. Voshol, Chantal Mathieu, Nadine Ectors, Wim J.M. Van de Ven and Catherine M. Verfaillie
    Diabetes 2010 Aug; 59 (8): 1957-1965. https://doi.org/10.2337/db09-1446
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Immunology and Transplantation

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    Deficiency in B7-H1 (PD-L1)/PD-1 Coinhibition Triggers Pancreatic β-Cell Destruction by Insulin-Specific, Murine CD8 T-Cells
    Tarvo Rajasalu, Helen Brosi, Cornelia Schuster, Andreas Spyrantis, Bernhard Otto Boehm, Lieping Chen, Jörg Reimann and Reinhold Schirmbeck
    Diabetes 2010 Aug; 59 (8): 1966-1973. https://doi.org/10.2337/db09-1135
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Pathophysiology

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    Decreased Circulating Progenitor Cell Number and Failed Mechanisms of Stromal Cell-Derived Factor-1α Mediated Bone Marrow Mobilization Impair Diabetic Tissue Repair
    Oren M. Tepper, Jacquelyn Carr, Robert J. Allen, Christopher C. Chang, Clarence D. Lin, Rica Tanaka, Sanjeev M. Gupta, Jamie P. Levine, Pierre B. Saadeh and Stephen M. Warren
    Diabetes 2010 Aug; 59 (8): 1974-1983. https://doi.org/10.2337/db09-0185
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    N-Glycosylation of Carnosinase Influences Protein Secretion and Enzyme ActivityImplications for Hyperglycemia
    Eva Riedl, Hannes Koeppel, Frederick Pfister, Verena Peters, Sibylle Sauerhoefer, Paula Sternik, Paul Brinkkoetter, Hanswalter Zentgraf, Gerjan Navis, Robert H. Henning, Jacob Van Den Born, Stephan J.L. Bakker, Bart Janssen, Fokko J. van der Woude and Benito A. Yard
    Diabetes 2010 Aug; 59 (8): 1984-1990. https://doi.org/10.2337/db09-0868
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    Control of Adipose Tissue Inflammation Through TRB1
    Anke Ostertag, Allan Jones, Adam J. Rose, Maria Liebert, Stefan Kleinsorg, Anja Reimann, Alexandros Vegiopoulos, Mauricio Berriel Diaz, Daniela Strzoda, Masahiro Yamamoto, Takashi Satoh, Shizuo Akira and Stephan Herzig
    Diabetes 2010 Aug; 59 (8): 1991-2000. https://doi.org/10.2337/db09-1537
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    Increased Cytochrome P4502E1 Expression and Altered Hydroxyeicosatetraenoic Acid Formation Mediate Diabetic Vascular DysfunctionRescue by Guanylyl-Cyclase Activation
    Andreas Schäfer, Paolo Galuppo, Daniela Fraccarollo, Christian Vogt, Julian D. Widder, Julia Pfrang, Piet Tas, Eduardo Barbosa-Sicard, Hartmut Ruetten, Georg Ertl, Ingrid Fleming and Johann Bauersachs
    Diabetes 2010 Aug; 59 (8): 2001-2009. https://doi.org/10.2337/db09-1668
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Complications

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    Transient Inhibition of Transforming Growth Factor-β1 in Human Diabetic CD34+ Cells Enhances Vascular Reparative Functions
    Ashay D. Bhatwadekar, E.P. Guerin, Yagna P.R. Jarajapu, Sergio Caballero, Carl Sheridan, David Kent, Laurence Kennedy, M. Cecilia Lansang, Frank W. Ruscetti, Carl J. Pepine, Paul J. Higgins, Stephen H. Bartelmez and Maria B. Grant
    Diabetes 2010 Aug; 59 (8): 2010-2019. https://doi.org/10.2337/db10-0287
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    The Association of Hemoglobin A1c With Incident Heart Failure Among People Without Diabetes: The Atherosclerosis Risk in Communities Study
    Kunihiro Matsushita, Saul Blecker, Antonio Pazin-Filho, Alain Bertoni, Patricia P. Chang, Josef Coresh and Elizabeth Selvin
    Diabetes 2010 Aug; 59 (8): 2020-2026. https://doi.org/10.2337/db10-0165
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    Higher Plasma Soluble Receptor for Advanced Glycation End Products (sRAGE) Levels Are Associated With Incident Cardiovascular Disease and All-Cause Mortality in Type 1 DiabetesA 12-Year Follow-Up Study
    Johanna W.M. Nin, Anders Jorsal, Isabel Ferreira, Casper G. Schalkwijk, Martin H. Prins, Hans-Henrik Parving, Lise Tarnow, Peter Rossing and Coen D.A. Stehouwer
    Diabetes 2010 Aug; 59 (8): 2027-2032. https://doi.org/10.2337/db09-1509
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    Deficiency of Rac1 Blocks NADPH Oxidase Activation, Inhibits Endoplasmic Reticulum Stress, and Reduces Myocardial Remodeling in a Mouse Model of Type 1 Diabetes
    Jianmin Li, Huaqing Zhu, E Shen, Li Wan, J. Malcolm O. Arnold and Tianqing Peng
    Diabetes 2010 Aug; 59 (8): 2033-2042. https://doi.org/10.2337/db09-1800
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    Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse
    Nina Reiniger, Kai Lau, Daren McCalla, Bonnie Eby, Bin Cheng, Yan Lu, Wu Qu, Nosirudeen Quadri, Radha Ananthakrishnan, Maryana Furmansky, Rosa Rosario, Fei Song, Vivek Rai, Alan Weinberg, Richard Friedman, Ravichandran Ramasamy, Vivette D'Agati and Ann Marie Schmidt
    Diabetes 2010 Aug; 59 (8): 2043-2054. https://doi.org/10.2337/db09-1766
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Genetics

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    HLA DPA1, DPB1 Alleles and Haplotypes Contribute to the Risk Associated With Type 1 DiabetesAnalysis of the Type 1 Diabetes Genetics Consortium Families
    Michael D. Varney, Ana Maria Valdes, Joyce A. Carlson, Janelle A. Noble, Brian D. Tait, Persia Bonella, Eva Lavant, Anna Lisa Fear, Anthony Louey, Priscilla Moonsamy, Josyf C. Mychaleckyj, Henry Erlich and for the Type 1 Diabetes Genetics Consortium
    Diabetes 2010 Aug; 59 (8): 2055-2062. https://doi.org/10.2337/db09-0680
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    BMI at Age 8 Years Is Influenced by the Type 2 Diabetes Susceptibility Genes HHEX-IDE and CDKAL1
    Christiane Winkler, Ezio Bonifacio, Harald Grallert, Lydia Henneberger, Thomas Illig and Anette-Gabriele Ziegler
    Diabetes 2010 Aug; 59 (8): 2063-2067. https://doi.org/10.2337/db10-0099
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    Impact of Common Variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the Risk of Type 2 Diabetes in 5,164 Indians
    Ganesh Chauhan, Charles J. Spurgeon, Rubina Tabassum, Seema Bhaskar, Smita R. Kulkarni, Anubha Mahajan, Sreenivas Chavali, M.V. Kranthi Kumar, Swami Prakash, Om Prakash Dwivedi, Saurabh Ghosh, Chittaranjan S. Yajnik, Nikhil Tandon, Dwaipayan Bharadwaj and Giriraj R. Chandak
    Diabetes 2010 Aug; 59 (8): 2068-2074. https://doi.org/10.2337/db09-1386
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    Replication Study for the Association Between Four Loci Identified by a Genome-Wide Association Study on European American Subjects With Type 1 Diabetes and Susceptibility to Diabetic Nephropathy in Japanese Subjects With Type 2 Diabetes
    Shiro Maeda, Shin-ichi Araki, Tetsuya Babazono, Masao Toyoda, Tomoya Umezono, Koichi Kawai, Masahito Imanishi, Takashi Uzu, Hirotaka Watada, Daisuke Suzuki, Atsunori Kashiwagi, Yasuhiko Iwamoto, Kohei Kaku, Ryuzo Kawamori and Yusuke Nakamura
    Diabetes 2010 Aug; 59 (8): 2075-2079. https://doi.org/10.2337/db10-0067
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    Functional Variants in MBL2 Are Associated With Type 2 Diabetes and Pre-Diabetes Traits in Pima Indians and the Old Order Amish
    Yunhua L. Muller, Robert L. Hanson, Li Bian, Janel Mack, Xiaolian Shi, Ruth Pakyz, Alan R. Shuldiner, William C. Knowler, Clifton Bogardus and Leslie J. Baier
    Diabetes 2010 Aug; 59 (8): 2080-2085. https://doi.org/10.2337/db09-1593
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In this Issue

August 2010, 59(8)
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