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Obesity Studies

Disruption of Hypoxia-Inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-Fat Diet–Fed Mice

  1. Changtao Jiang1,
  2. Aijuan Qu1,
  3. Tsutomu Matsubara1,
  4. Tatyana Chanturiya2,
  5. William Jou2,
  6. Oksana Gavrilova2,
  7. Yatrik M. Shah1,3 and
  8. Frank J. Gonzalez1⇓
  1. 1Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland
  2. 2Mouse Metabolism Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
  3. 3Division of Gastroenterology, Department of Molecular and Integrative Physiology and Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan
  1. Corresponding author: Frank J. Gonzalez, gonzalef{at}mail.nih.gov.
Diabetes 2011 Oct; 60(10): 2484-2495. https://doi.org/10.2337/db11-0174
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Diabetes: 60 (10)

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October 2011, 60(10)
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Disruption of Hypoxia-Inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-Fat Diet–Fed Mice
Changtao Jiang, Aijuan Qu, Tsutomu Matsubara, Tatyana Chanturiya, William Jou, Oksana Gavrilova, Yatrik M. Shah, Frank J. Gonzalez
Diabetes Oct 2011, 60 (10) 2484-2495; DOI: 10.2337/db11-0174

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Disruption of Hypoxia-Inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-Fat Diet–Fed Mice
Changtao Jiang, Aijuan Qu, Tsutomu Matsubara, Tatyana Chanturiya, William Jou, Oksana Gavrilova, Yatrik M. Shah, Frank J. Gonzalez
Diabetes Oct 2011, 60 (10) 2484-2495; DOI: 10.2337/db11-0174
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  • Placental Insulin/IGF-1 Signaling, PGC-1α, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4–6 Years of Age: The ECHO Healthy Start Cohort
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