Diabetes: 60 (8)

August 01 2011; volume 60 issue 8

Perspectives in Diabetes

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The Metabolically Benign and Malignant Fatty Liver
Norbert Stefan and Hans-Ulrich Häring

Diabetes 2011 Aug; 60 (8): 2011-2017. https://doi.org/10.2337/db11-0231

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Commentaries

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Sleeping Islets and the Relationship Between β-Cell Mass and Function
Gordon C. Weir and Susan Bonner-Weir

Diabetes 2011 Aug; 60 (8): 2018-2019. https://doi.org/10.2337/db10-1808

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To B or Not to B: (Anti)bodies of Evidence on the Crime Scene of Type 1 Diabetes?
Roberto Mallone and Vedran Brezar

Diabetes 2011 Aug; 60 (8): 2020-2022. https://doi.org/10.2337/db11-0700

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Metabolism

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Macrophage Deletion of SOCS1 Increases Sensitivity to LPS and Palmitic Acid and Results in Systemic Inflammation and Hepatic Insulin Resistance
Nirupa Sachithanandan, Kate L. Graham, Sandra Galic, Jane E. Honeyman, Stacey L. Fynch, Kimberly A. Hewitt, Gregory R. Steinberg and Thomas W. Kay

Diabetes 2011 Aug; 60 (8): 2023-2031. https://doi.org/10.2337/db11-0259

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Storage of Circulating Free Fatty Acid in Adipose Tissue of Postabsorptive HumansQuantitative Measures and Implications for Body Fat Distribution
Christina Koutsari, Asem H. Ali, Manpreet S. Mundi and Michael D. Jensen

Diabetes 2011 Aug; 60 (8): 2032-2040. https://doi.org/10.2337/db11-0154

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Severity of Diabetes Governs Vascular Lipoprotein Lipase by Affecting Enzyme Dimerization and Disassembly
Ying Wang, Prasanth Puthanveetil, Fang Wang, Min Suk Kim, Ashraf Abrahani and Brian Rodrigues

Diabetes 2011 Aug; 60 (8): 2041-2050. https://doi.org/10.2337/db11-0042

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Reduction in Reactive Oxygen Species Production by Mitochondria From Elderly Subjects With Normal and Impaired Glucose Tolerance
Sangeeta Ghosh, Raweewan Lertwattanarak, Natalie Lefort, Marjorie Molina-Carrion, Joaquin Joya-Galeana, Benjamin P. Bowen, Jose de Jesus Garduno-Garcia, Muhammad Abdul-Ghani, Arlan Richardson, Ralph A. DeFronzo, Lawrence Mandarino, Holly Van Remmen and Nicolas Musi

Diabetes 2011 Aug; 60 (8): 2051-2060. https://doi.org/10.2337/db11-0121

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Endothelin-1 Reduces Glucose Uptake in Human Skeletal Muscle In Vivo and In Vitro
Alexey Shemyakin, Firoozeh Salehzadeh, Daniella Esteves Duque-Guimaraes, Felix Böhm, Eric Rullman, Thomas Gustafsson, John Pernow and Anna Krook

Diabetes 2011 Aug; 60 (8): 2061-2067. https://doi.org/10.2337/db10-1281

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A Low-Oxygenated Subpopulation of Pancreatic Islets Constitutes a Functional Reserve of Endocrine Cells
Richard Olsson and Per-Ola Carlsson

Diabetes 2011 Aug; 60 (8): 2068-2075. https://doi.org/10.2337/db09-0877

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Islet Studies

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Heterozygous Inactivation of the Na/Ca Exchanger Increases Glucose-Induced Insulin Release, β-Cell Proliferation, and Mass
Evrard Nguidjoe, Sophie Sokolow, Serge Bigabwa, Nathalie Pachera, Eva D'Amico, Florent Allagnat, Jean-Marie Vanderwinden, Abdullah Sener, Mario Manto, Marianne Depreter, Jan Mast, Geraldine Joanny, Eduard Montanya, Jacques Rahier, Alessandra K. Cardozo, Décio L. Eizirik, Stéphane Schurmans and André Herchuelz

Diabetes 2011 Aug; 60 (8): 2076-2085. https://doi.org/10.2337/db10-0924

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Progressive Erosion of β-Cell Function Precedes the Onset of Hyperglycemia in the NOD Mouse Model of Type 1 Diabetes
Diego Ize-Ludlow, Yaima L. Lightfoot, Matthew Parker, Song Xue, Clive Wasserfall, Michael J. Haller, Desmond Schatz, Dorothy J. Becker, Mark A. Atkinson and Clayton E. Mathews

Diabetes 2011 Aug; 60 (8): 2086-2091. https://doi.org/10.2337/db11-0373

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In Vivo Misfolding of Proinsulin Below the Threshold of Frank Diabetes
Israel Hodish, Afaf Absood, Leanza Liu, Ming Liu, Leena Haataja, Dennis Larkin, Ahmed Al-Khafaji, Anthony Zaki and Peter Arvan

Diabetes 2011 Aug; 60 (8): 2092-2101. https://doi.org/10.2337/db10-1671

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Immunology and Transplantation

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Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells
Diego G. Silva, Stephen R. Daley, Jennifer Hogan, Sau K. Lee, Charis E. Teh, Daniel Y. Hu, Kong-Peng Lam, Christopher C. Goodnow and Carola G. Vinuesa

Diabetes 2011 Aug; 60 (8): 2102-2111. https://doi.org/10.2337/db10-1344

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Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death
Sefina Arif, Fabrice Moore, Katherine Marks, Thomas Bouckenooghe, Colin M. Dayan, Raquel Planas, Marta Vives-Pi, Jake Powrie, Timothy Tree, Piero Marchetti, Guo Cai Huang, Esteban N. Gurzov, Ricardo Pujol-Borrell, Decio L. Eizirik and Mark Peakman

Diabetes 2011 Aug; 60 (8): 2112-2119. https://doi.org/10.2337/db10-1643

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Defective Differentiation of Regulatory FoxP3⁺ T Cells by Small-Intestinal Dendritic Cells in Patients With Type 1 Diabetes
Ester Badami, Chiara Sorini, Margherita Coccia, Vera Usuelli, Laura Molteni, Andrea Mario Bolla, Marina Scavini, Alberto Mariani, Cecile King, Emanuele Bosi and Marika Falcone

Diabetes 2011 Aug; 60 (8): 2120-2124. https://doi.org/10.2337/db10-1201

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Uncoupling of Proliferation and Cytokines From Suppression Within the CD4+CD25+Foxp3+ T–Cell Compartment in the 1st Year of Human Type 1 Diabetes
Angela Hughson, Irina Bromberg, Barbara Johnson, Sally Quataert, Nicholas Jospe and Deborah J. Fowell

Diabetes 2011 Aug; 60 (8): 2125-2133. https://doi.org/10.2337/db10-1661

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High-Fat Diet–Induced Adipocyte Cell Death Occurs Through a Cyclophilin D Intrinsic Signaling Pathway Independent of Adipose Tissue Inflammation
Daorong Feng, Yan Tang, Hyokjoon Kwon, Haihong Zong, Meredith Hawkins, Richard N. Kitsis and Jeffrey E. Pessin

Diabetes 2011 Aug; 60 (8): 2134-2143. https://doi.org/10.2337/db10-1411

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Superoxide Production by Macrophages and T Cells Is Critical for the Induction of Autoreactivity and Type 1 Diabetes
Terri C. Thayer, Matthew Delano, Chao Liu, Jing Chen, Lindsey E. Padgett, Hubert M. Tse, Mani Annamali, Jon D. Piganelli, Lyle L. Moldawer and Clayton E. Mathews

Diabetes 2011 Aug; 60 (8): 2144-2151. https://doi.org/10.2337/db10-1222

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Pathophysiology

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Higher Cord C-Peptide Concentrations Are Associated With Slower Growth Rate in the 1st Year of Life in Girls but Not in Boys
Nolwenn Regnault, Jérémie Botton, Barbara Heude, Anne Forhan, Régis Hankard, Bernard Foliguet, Teresa A. Hillier, Jean-Claude Souberbielle, Patricia Dargent-Molina, Marie-Aline Charles and the EDEN Mother-Child Cohort Study Group

Diabetes 2011 Aug; 60 (8): 2152-2159. https://doi.org/10.2337/db10-1189

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Loss of Inverse Relationship Between Pulsatile Insulin and Glucagon Secretion in Patients With Type 2 Diabetes
Björn A. Menge, Lena Grüber, Signe M. Jørgensen, Carolyn F. Deacon, Wolfgang E. Schmidt, Johannes D. Veldhuis, Jens J. Holst and Juris J. Meier

Diabetes 2011 Aug; 60 (8): 2160-2168. https://doi.org/10.2337/db11-0251

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The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium
Afroze Abbas, Helen Imrie, Hema Viswambharan, Piruthivi Sukumar, Adil Rajwani, Richard M. Cubbon, Matthew Gage, Jessica Smith, Stacey Galloway, Nadira Yuldeshava, Matthew Kahn, Shouhong Xuan, Peter J. Grant, Keith M. Channon, David J. Beech, Stephen B. Wheatcroft and Mark T. Kearney

Diabetes 2011 Aug; 60 (8): 2169-2178. https://doi.org/10.2337/db11-0197

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CD14 Modulates Inflammation-Driven Insulin Resistance
José Manuel Fernández-Real, Sofia Pérez del Pulgar, Elodie Luche, José Maria Moreno-Navarrete, Aurelie Waget, Matteo Serino, Eleonora Sorianello, Alex Sánchez-Pla, Francesc Carmona Pontaque, Joan Vendrell, Matilde R. Chacón, Wifredo Ricart, Remy Burcelin and Antonio Zorzano

Diabetes 2011 Aug; 60 (8): 2179-2186. https://doi.org/10.2337/db10-1210

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Complications

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The RANKL/RANK/OPG Signaling Pathway Mediates Medial Arterial Calcification in Diabetic Charcot Neuroarthropathy
Agbor Ndip, Alfred Williams, Edward B. Jude, Ferdinand Serracino-Inglott, Steve Richardson, J.V. Smyth, Andrew J.M. Boulton and M. Yvonne Alexander

Diabetes 2011 Aug; 60 (8): 2187-2196. https://doi.org/10.2337/db10-1220

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Genetics

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Novel Locus FER Is Associated With Serum HMW Adiponectin Levels
Lu Qi, Claudia Menzaghi, Lucia Salvemini, Concetta De Bonis, Vincenzo Trischitta and Frank B. Hu

Diabetes 2011 Aug; 60 (8): 2197-2201. https://doi.org/10.2337/db10-1645

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Issues and Events

Open Access
Issues and Events
Diabetes 2011 Aug; 60 (8): 2202. https://doi.org/10.2337/db11-ie08

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Online Letters to the Editor

Open Access
Comment on: Ott et al. Reduction in Basal Nitric Oxide Activity Causes Albuminuria. Diabetes 2011;60:572–576
Dimitrios Tsikas, Stefan Engeli, Jens Tank, Dirk O. Stichtenoth and Jens Jordan

Diabetes 2011 Aug; 60 (8): e21. https://doi.org/10.2337/db11-0519

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Open Access
Response to Comment on: Ott et al. Reduction in Basal Nitric Oxide Activity Causes Albuminuria. Diabetes 2011;60:572–576
Christian Ott, Markus P. Schneider and Roland E. Schmieder

Diabetes 2011 Aug; 60 (8): e22. https://doi.org/10.2337/db11-0602

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Table of Contents

Perspectives in Diabetes

Commentaries

Metabolism

Islet Studies

Immunology and Transplantation

Pathophysiology

Complications

Genetics

Issues and Events

Online Letters to the Editor

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