Evidence That Hyperglycemia After Recovery From Hypoglycemia Worsens Endothelial Function and Increases Oxidative Stress and Inflammation in Healthy Control Subjects and Subjects With Type 1 Diabetes
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Figures
- FIG. 1.
Levels for glucose, sICAM-1, FMD, nitrotyrosine, IL-6, and 8-iso-PGF2α in type 1 diabetes are shown for hypoglycemia + hyperglycemia (solid line), hypoglycemia + normoglycemia (dashed line), and hypoglycemia + hyperglycemia + vitamin C (dashed-dotted line). *P < 0.05 vs. basal. #P < 0.01 vs. basal. §P < 0.01 vs. hypoglycemia + normoglycemia. “P < 0.05 vs. hypoglycemia + normoglycemia. P < 0.01 vs. hypoglycemia + hyperglycemia + vitamin C.
- FIG. 2.
Levels for glucose, sICAM-1, FMD, nitrotyrosine, IL-6, and 8-iso-PGF2α in normal healthy control subjects are shown for hypoglycemia + hyperglycemia (solid line), hypoglycemia + normoglycemia (dashed line), and hypoglycemia + hyperglycemia + vitamin C (dashed-dotted line). *P < 0.05 vs. basal. #P < 0.01 vs. basal. §P < 0.01 vs. hypoglycemia + normoglycemia. P < 0.01 vs. hypoglycemia + hyperglycemia + vitamin C.
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