Signal Transduction

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein–Coupled Receptor FFAR2

  1. Gwen Tolhurst1,
  2. Helen Heffron2,
  3. Yu Shan Lam1,
  4. Helen E. Parker1,
  5. Abdella M. Habib1,
  6. Eleftheria Diakogiannaki1,
  7. Jennifer Cameron2,
  8. Johannes Grosse2,
  9. Frank Reimann1⇓ and
  10. Fiona M. Gribble1⇓
  1. 1Cambridge Institute for Medical Research, Wellcome Trust/Medical Research Council Building, Addenbrooke’s Hospital, Cambridge, U.K.
  2. 2Takeda Cambridge Ltd, Cambridge, U.K.
  1. Corresponding authors: Fiona M. Gribble, fmg23{at}cam.ac.uk, and Frank Reimann, fr222{at}cam.ac.uk.

  1. G.T. and H.H. contributed equally to this work.

Diabetes 2012 Feb; 61(2): 364-371. https://doi.org/10.2337/db11-1019

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February 2012, 61(2)
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Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein–Coupled Receptor FFAR2
Gwen Tolhurst, Helen Heffron, Yu Shan Lam, Helen E. Parker, Abdella M. Habib, Eleftheria Diakogiannaki, Jennifer Cameron, Johannes Grosse, Frank Reimann, Fiona M. Gribble
Diabetes Feb 2012, 61 (2) 364-371; DOI: 10.2337/db11-1019
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