Diabetes: 61 (3)

March 01 2012; volume 61 issue 3

Perspectives in Diabetes

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Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications
Ryoji Nagai, David B. Murray, Thomas O. Metz and John W. Baynes

Diabetes 2012 Mar; 61 (3): 549-559. https://doi.org/10.2337/db11-1120

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Commentaries

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Does Inhibition of β-Cell Proliferation by Free Fatty Acid in Mice Explain the Progressive Failure of Insulin Secretion in Type 2 Diabetes?
Guenther Boden

Diabetes 2012 Mar; 61 (3): 560-561. https://doi.org/10.2337/db11-1613

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Predicting Diabetes Using Measures of β-Cell Function
Adrian Vella and Alan R. Zinsmeister

Diabetes 2012 Mar; 61 (3): 562-563. https://doi.org/10.2337/db11-1785

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Hypothalamic Regulation of Glucose-Stimulated Insulin Secretion
Owen Chan and Robert S. Sherwin

Diabetes 2012 Mar; 61 (3): 564-565. https://doi.org/10.2337/db11-1846

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Metabolism

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Hepatic TRAF2 Regulates Glucose Metabolism Through Enhancing Glucagon Responses
Zheng Chen, Liang Sheng, Hong Shen, Yujun Zhao, Shaomeng Wang, Robert Brink and Liangyou Rui

Diabetes 2012 Mar; 61 (3): 566-573. https://doi.org/10.2337/db11-0474

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Signal Transduction

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Glucose-Induced Nuclear Shuttling of ChREBP Is Mediated by Sorcin and Ca²⁺ Ions in Pancreatic β-Cells
Nafeesa A. Noordeen, Gargi Meur, Guy A. Rutter and Isabelle Leclerc

Diabetes 2012 Mar; 61 (3): 574-585. https://doi.org/10.2337/db10-1329

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Thiazolidinedione Treatment Decreases Oxidative Stress in Spontaneously Hypertensive Heart Failure Rats Through Attenuation of Inducible Nitric Oxide Synthase–Mediated Lipid Radical Formation
Maria B. Kadiiska, Marcelo G. Bonini, Christine Ruggiero, Ellen Cleland, Shawna Wicks and Krisztian Stadler

Diabetes 2012 Mar; 61 (3): 586-596. https://doi.org/10.2337/db11-1091

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Bioactives of Artemisia dracunculus L. Mitigate the Role of Ceramides in Attenuating Insulin Signaling in Rat Skeletal Muscle Cells
Diana N. Obanda, Amy Hernandez, David Ribnicky, Yongmei Yu, Xian H. Zhang, Zhong Q. Wang and William T. Cefalu

Diabetes 2012 Mar; 61 (3): 597-605. https://doi.org/10.2337/db11-0396

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Obesity Studies

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Evidence for Early Defects in Insulin Sensitivity and Secretion Before the Onset of Glucose Dysregulation in Obese YouthsA Longitudinal Study
Cosimo Giannini, Ram Weiss, Anna Cali, Riccardo Bonadonna, Nicola Santoro, Bridget Pierpont, Melissa Shaw and Sonia Caprio

Diabetes 2012 Mar; 61 (3): 606-614. https://doi.org/10.2337/db11-1111

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Heat Shock Protein 60 as a Mediator of Adipose Tissue Inflammation and Insulin Resistance
Tina Märker, Henrike Sell, Pia Zilleßen, Anja Glöde, Jennifer Kriebel, D. Margriet Ouwens, Piet Pattyn, Johannes Ruige, Susanne Famulla, Michael Roden, Jürgen Eckel and Christiane Habich

Diabetes 2012 Mar; 61 (3): 615-625. https://doi.org/10.2337/db10-1574

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Common Variants of IL6, LEPR, and PBEF1 Are Associated With Obesity in Indian Children
Rubina Tabassum, Yuvaraj Mahendran, Om Prakash Dwivedi, Ganesh Chauhan, Saurabh Ghosh, Raman K. Marwaha, Nikhil Tandon and Dwaipayan Bharadwaj

Diabetes 2012 Mar; 61 (3): 626-631. https://doi.org/10.2337/db11-1501

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Islet Studies

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Free Fatty Acids Block Glucose-Induced β-Cell Proliferation in Mice by Inducing Cell Cycle Inhibitors p16 and p18
Jordan Pascoe, Douglas Hollern, Rachel Stamateris, Munira Abbasi, Lia C. Romano, Baobo Zou, Christopher P. O’Donnell, Adolfo Garcia-Ocana and Laura C. Alonso

Diabetes 2012 Mar; 61 (3): 632-641. https://doi.org/10.2337/db11-0991

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Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism That Prevents High-Fat Diet–Induced β-Cell Failure
Sophie Turban, Xiaoxia Liu, Lynne Ramage, Scott P. Webster, Brian R. Walker, Donald R. Dunbar, John J. Mullins, Jonathan R. Seckl and Nicholas M. Morton

Diabetes 2012 Mar; 61 (3): 642-652. https://doi.org/10.2337/db11-1054

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miR-33a Modulates ABCA1 Expression, Cholesterol Accumulation, and Insulin Secretion in Pancreatic Islets
Nadeeja Wijesekara, Lin-hua Zhang, Martin H. Kang, Thomas Abraham, Alpana Bhattacharjee, Garth L. Warnock, C. Bruce Verchere and Michael R. Hayden

Diabetes 2012 Mar; 61 (3): 653-658. https://doi.org/10.2337/db11-0944

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Loss of Both ABCA1 and ABCG1 Results in Increased Disturbances in Islet Sterol Homeostasis, Inflammation, and Impaired β-Cell Function
Janine K. Kruit, Nadeeja Wijesekara, Clara Westwell-Roper, Tim Vanmierlo, Willeke de Haan, Alpana Bhattacharjee, Renmei Tang, Cheryl L. Wellington, Dieter LütJohann, James D. Johnson, Liam R. Brunham, C. Bruce Verchere and Michael R. Hayden

Diabetes 2012 Mar; 61 (3): 659-664. https://doi.org/10.2337/db11-1341

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Immunology and Transplantation

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Markedly Decreased Blood Perfusion of Pancreatic Islets Transplanted Intraportally Into the LiverDisruption of Islet Integrity Necessary for Islet Revascularization
Johanna Henriksnäs, Joey Lau, Guangxiang Zang, Per-Olof Berggren, Martin Köhler and Per-Ola Carlsson

Diabetes 2012 Mar; 61 (3): 665-673. https://doi.org/10.2337/db10-0895

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Reversal of Type 1 Diabetes in Mice by Brown Adipose Tissue Transplant
Subhadra C. Gunawardana and David W. Piston

Diabetes 2012 Mar; 61 (3): 674-682. https://doi.org/10.2337/db11-0510

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Rising Incidence of Type 1 Diabetes Is Associated With Altered Immunophenotype at Diagnosis
Anna E. Long, Kathleen M. Gillespie, Saba Rokni, Polly J. Bingley and Alistair J.K. Williams

Diabetes 2012 Mar; 61 (3): 683-686. https://doi.org/10.2337/db11-0962

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Pathophysiology

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Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa
Maarit Oikarinen, Sisko Tauriainen, Sami Oikarinen, Teemu Honkanen, Pekka Collin, Immo Rantala, Markku Mäki, Katri Kaukinen and Heikki Hyöty

Diabetes 2012 Mar; 61 (3): 687-691. https://doi.org/10.2337/db11-1157

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Age-Related Impairment in Insulin ReleaseThe Essential Role of β₂-Adrenergic Receptor
Gaetano Santulli, Angela Lombardi, Daniela Sorriento, Antonio Anastasio, Carmine Del Giudice, Pietro Formisano, Francesco Béguinot, Bruno Trimarco, Claudia Miele and Guido Iaccarino

Diabetes 2012 Mar; 61 (3): 692-701. https://doi.org/10.2337/db11-1027

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Interbirth Interval Is Associated With Childhood Type 1 Diabetes Risk
Chris R. Cardwell, Jannet Svensson, Thomas Waldhoer, Johnny Ludvigsson, Vaiva Sadauskaitė-Kuehne, Christine L. Roberts, Roger C. Parslow, Emma J.K. Wadsworth, Girts Brigis, Brone Urbonaitė, Edith Schober, Gabriele Devoti, Constantin Ionescu-Tirgoviste, Carine E. de Beaufort, Gyula Soltesz and Chris C. Patterson

Diabetes 2012 Mar; 61 (3): 702-707. https://doi.org/10.2337/db11-1000

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Complications

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Glycemic Control and Cardiovascular Mortality in Hemodialysis Patients With DiabetesA 6-Year Cohort Study
Joni Ricks, Miklos Z. Molnar, Csaba P. Kovesdy, Anuja Shah, Allen R. Nissenson, Mark Williams and Kamyar Kalantar-Zadeh

Diabetes 2012 Mar; 61 (3): 708-715. https://doi.org/10.2337/db11-1015

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Cannabinoid 1 Receptor Promotes Cardiac Dysfunction, Oxidative Stress, Inflammation, and Fibrosis in Diabetic Cardiomyopathy
Mohanraj Rajesh, Sándor Bátkai, Malek Kechrid, Partha Mukhopadhyay, Wen-Shin Lee, Béla Horváth, Eileen Holovac, Resat Cinar, Lucas Liaudet, Ken Mackie, György Haskó and Pál Pacher

Diabetes 2012 Mar; 61 (3): 716-727. https://doi.org/10.2337/db11-0477

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Catalase Deficiency Accelerates Diabetic Renal Injury Through Peroxisomal Dysfunction
Inah Hwang, Jiyoun Lee, Joo Young Huh, Jehyun Park, Hi Bahl Lee, Ye-Shih Ho and Hunjoo Ha

Diabetes 2012 Mar; 61 (3): 728-738. https://doi.org/10.2337/db11-0584

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Gene Expression Differences in Skin Fibroblasts in Identical Twins Discordant for Type 1 Diabetes
M. Luiza Caramori, Youngki Kim, Jason H. Moore, Stephen S. Rich, Josyf C. Mychaleckyj, Nobuaki Kikyo and Michael Mauer

Diabetes 2012 Mar; 61 (3): 739-744. https://doi.org/10.2337/db11-0617

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Genetics/Genomes/Proteomics/Metabolomics

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Genetic Predisposition to Dyslipidemia and Type 2 Diabetes Risk in Two Prospective Cohorts
Qibin Qi, Liming Liang, Alessandro Doria, Frank B. Hu and Lu Qi

Diabetes 2012 Mar; 61 (3): 745-752. https://doi.org/10.2337/db11-1254

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Effects of Non-HLA Gene Polymorphisms on Development of Islet Autoimmunity and Type 1 Diabetes in a Population With High-Risk HLA-DR,DQ Genotypes
Andrea K. Steck, Randall Wong, Brandie Wagner, Kelly Johnson, Edwin Liu, Jihane Romanos, Cisca Wijmenga, Jill M. Norris, George S. Eisenbarth and Marian J. Rewers

Diabetes 2012 Mar; 61 (3): 753-758. https://doi.org/10.2337/db11-1228

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Erratum

Open Access
Erratum
Diabetes 2012 Mar; 61 (3): 759. https://doi.org/10.2337/db12-er03

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Issues and Events

Open Access
Issues and Events
Diabetes 2012 Mar; 61 (3): 760. https://doi.org/10.2337/db12-ie03

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Table of Contents

Perspectives in Diabetes

Commentaries

Metabolism

Signal Transduction

Obesity Studies

Islet Studies

Immunology and Transplantation

Pathophysiology

Complications

Genetics/Genomes/Proteomics/Metabolomics

Erratum

Issues and Events

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