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Table of Contents

PreviousNext

November 01 2013; volume 62 issue 11

In This Issue

  • Open Access
    In This Issue of Diabetes
    Diabetes 2013 Nov; 62 (11): 3645-3646. https://doi.org/10.2337/db13-ti11
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Perspectives in Diabetes

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    Endothelial-Podocyte Crosstalk: The Missing Link Between Endothelial Dysfunction and Albuminuria in Diabetes
    Ferhan S. Siddiqi and Andrew Advani
    Diabetes 2013 Nov; 62 (11): 3647-3655. https://doi.org/10.2337/db13-0795
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Commentaries

  • Open Access
    The Compelling Case for Anti-CD3 in Type 1 Diabetes
    Jay S. Skyler
    Diabetes 2013 Nov; 62 (11): 3656-3657. https://doi.org/10.2337/db13-1157
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  • Open Access
    Location, Location, Location?Is the Pain of Diabetic Neuropathy Generated by Hyperactive Sensory Neurons?
    Nigel A. Calcutt
    Diabetes 2013 Nov; 62 (11): 3658-3660. https://doi.org/10.2337/db13-1158
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  • Open Access
    Cholesterol Accumulation in Podocytes: A Potential Novel Targetable Pathway in Diabetic Nephropathy
    Alda Tufro
    Diabetes 2013 Nov; 62 (11): 3661-3662. https://doi.org/10.2337/db13-1167
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  • Open Access
    How Does Pioglitazone Prevent Progression of Impaired Glucose Tolerance to Diabetes?
    Saul M. Genuth
    Diabetes 2013 Nov; 62 (11): 3663-3665. https://doi.org/10.2337/db13-1175
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  • Open Access
    ATP and Sulfonylurea Linkage in the KATP Channel Solves a Diabetes Puzzler
    Peter Drain
    Diabetes 2013 Nov; 62 (11): 3666-3668. https://doi.org/10.2337/db13-1194
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  • Open Access
    Depleting T Cells in Newly Diagnosed Autoimmune (Type 1) Diabetes—Are We Getting Anywhere?
    Åke Lernmark
    Diabetes 2013 Nov; 62 (11): 3669-3670. https://doi.org/10.2337/db13-1207
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  • Open Access
    Going With the Flow: Adaptation of β-Cell Function to Glucose Fluxes After Bariatric Surgery
    Marzieh Salehi and David A. D’Alessio
    Diabetes 2013 Nov; 62 (11): 3671-3673. https://doi.org/10.2337/db13-1213
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  • Open Access
    GABAergic System in β-Cells: From Autoimmunity Target to Regeneration Tool
    Paolo Fiorina
    Diabetes 2013 Nov; 62 (11): 3674-3676. https://doi.org/10.2337/db13-1243
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Methodology Review

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    Assessing Decreased Sensation and Increased Sensory Phenomena in Diabetic Polyneuropathies
    Peter J. Dyck, David N. Herrmann, Nathan P. Staff and P. James B. Dyck
    Diabetes 2013 Nov; 62 (11): 3677-3686. https://doi.org/10.2337/db13-0352
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Technological Advances

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    Age-Dependent Labeling and Imaging of Insulin Secretory Granules
    Anna Ivanova, Yannis Kalaidzidis, Ronald Dirkx, Mihail Sarov, Michael Gerlach, Britta Schroth-Diez, Andreas Müller, Yanmei Liu, Cordula Andree, Bernard Mulligan, Carla Münster, Thomas Kurth, Marc Bickle, Stephan Speier, Konstantinos Anastassiadis and Michele Solimena
    Diabetes 2013 Nov; 62 (11): 3687-3696. https://doi.org/10.2337/db12-1819
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Metabolism

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    Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity
    Stefania Carobbio, Rachel M. Hagen, Christopher J. Lelliott, Marc Slawik, Gema Medina-Gomez, Chong-Yew Tan, Audrey Sicard, Helen J. Atherton, Nuria Barbarroja, Mikael Bjursell, Mohammad Bohlooly-Y, Sam Virtue, Antoinette Tuthill, Etienne Lefai, Martine Laville, Tingting Wu, Robert V. Considine, Hubert Vidal, Dominique Langin, Matej Oresic, Francisco J. Tinahones, Jose Manuel Fernandez-Real, Julian L. Griffin, Jaswinder K. Sethi, Miguel López and Antonio Vidal-Puig
    Diabetes 2013 Nov; 62 (11): 3697-3708. https://doi.org/10.2337/db12-1748
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Obesity Studies

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    Long-Term Effects of Bariatric Surgery on Meal Disposal and β-Cell Function in Diabetic and Nondiabetic Patients
    Stefania Camastra, Elza Muscelli, Amalia Gastaldelli, Jens J. Holst, Brenno Astiarraga, Simona Baldi, Monica Nannipieri, Demetrio Ciociaro, Marco Anselmino, Andrea Mari and Ele Ferrannini
    Diabetes 2013 Nov; 62 (11): 3709-3717. https://doi.org/10.2337/db13-0321
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    Profilin-1 Haploinsufficiency Protects Against Obesity-Associated Glucose Intolerance and Preserves Adipose Tissue Immune Homeostasis
    Giulio R. Romeo, Munkyong Pae, Delphine Eberlé, Jongsoon Lee and Steven E. Shoelson
    Diabetes 2013 Nov; 62 (11): 3718-3726. https://doi.org/10.2337/db13-0050
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    Maternal Obesity Induces Epigenetic Modifications to Facilitate Zfp423 Expression and Enhance Adipogenic Differentiation in Fetal Mice
    Qi-Yuan Yang, Jun-Fang Liang, Carl J. Rogers, Jun-Xing Zhao, Mei-Jun Zhu and Min Du
    Diabetes 2013 Nov; 62 (11): 3727-3735. https://doi.org/10.2337/db13-0433
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    Overnutrition Stimulates Intestinal Epithelium Proliferation Through β-Catenin Signaling in Obese Mice
    Jiaming Mao, Xiaomin Hu, Yao Xiao, Chao Yang, Yi Ding, Ning Hou, Jue Wang, Heping Cheng and Xiuqin Zhang
    Diabetes 2013 Nov; 62 (11): 3736-3746. https://doi.org/10.2337/db13-0035
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    Downregulation of CPPED1 Expression Improves Glucose Metabolism In Vitro in Adipocytes
    Maija Vaittinen, Dorota Kaminska, Pirjo Käkelä, Matti Eskelinen, Marjukka Kolehmainen, Jussi Pihlajamäki, Matti Uusitupa and Leena Pulkkinen
    Diabetes 2013 Nov; 62 (11): 3747-3750. https://doi.org/10.2337/db13-0830
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Islet Studies

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    High Glucose Represses β-Klotho Expression and Impairs Fibroblast Growth Factor 21 Action in Mouse Pancreatic IsletsInvolvement of Peroxisome Proliferator–Activated Receptor γ Signaling
    Wing Yan So, Qianni Cheng, Lihua Chen, Carmella Evans-Molina, Aimin Xu, Karen S.L. Lam and Po Sing Leung
    Diabetes 2013 Nov; 62 (11): 3751-3759. https://doi.org/10.2337/db13-0645
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    γ-Aminobutyric Acid Regulates Both the Survival and Replication of Human β-Cells
    Jide Tian, Hoa Dang, Zheying Chen, Alice Guan, Yingli Jin, Mark A. Atkinson and Daniel L. Kaufman
    Diabetes 2013 Nov; 62 (11): 3760-3765. https://doi.org/10.2337/db13-0931
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Immunology and Transplantation

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    Teplizumab (Anti-CD3 mAb) Treatment Preserves C-Peptide Responses in Patients With New-Onset Type 1 Diabetes in a Randomized Controlled TrialMetabolic and Immunologic Features at Baseline Identify a Subgroup of Responders
    Kevan C. Herold, Stephen E. Gitelman, Mario R. Ehlers, Peter A. Gottlieb, Carla J. Greenbaum, William Hagopian, Karen D. Boyle, Lynette Keyes-Elstein, Sudeepta Aggarwal, Deborah Phippard, Peter H. Sayre, James McNamara, Jeffrey A. Bluestone and and the AbATE Study Team
    Diabetes 2013 Nov; 62 (11): 3766-3774. https://doi.org/10.2337/db13-0345
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    β-Cell–Specific IL-2 Therapy Increases Islet Foxp3+Treg and Suppresses Type 1 Diabetes in NOD Mice
    Mark C. Johnson, Alaina L. Garland, Sarah C. Nicolson, Chengwen Li, R. Jude Samulski, Bo Wang and Roland Tisch
    Diabetes 2013 Nov; 62 (11): 3775-3784. https://doi.org/10.2337/db13-0669
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    Protection Against Type 1 Diabetes Upon Coxsackievirus B4 Infection and iNKT-Cell StimulationRole of Suppressive Macrophages
    Liana Ghazarian, Julien Diana, Lucie Beaudoin, Pär G. Larsson, Raj K. Puri, Nico van Rooijen, Malin Flodström-Tullberg and Agnès Lehuen
    Diabetes 2013 Nov; 62 (11): 3785-3796. https://doi.org/10.2337/db12-0958
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Pathophysiology

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    A Mouse Model of Human Hyperinsulinism Produced by the E1506K Mutation in the Sulphonylurea Receptor SUR1
    Kenju Shimomura, Maija Tusa, Michaela Iberl, Melissa F. Brereton, Stephan Kaizik, Peter Proks, Carolina Lahmann, Nagendra Yaluri, Shalem Modi, Hanna Huopio, Jarkko Ustinov, Timo Otonkoski, Markku Laakso and Frances M. Ashcroft
    Diabetes 2013 Nov; 62 (11): 3797-3806. https://doi.org/10.2337/db12-1611
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    Elastin-Derived Peptides Are New Regulators of Insulin Resistance Development in Mice
    Sébastien Blaise, Béatrice Romier, Charlotte Kawecki, Maxime Ghirardi, Fanja Rabenoelina, Stéphanie Baud, Laurent Duca, Pascal Maurice, Andrea Heinz, Christian E.H. Schmelzer, Michel Tarpin, Laurent Martiny, Christian Garbar, Manuel Dauchez, Laurent Debelle and Vincent Durlach
    Diabetes 2013 Nov; 62 (11): 3807-3816. https://doi.org/10.2337/db13-0508
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Complications

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    Cyclodextrin Protects Podocytes in Diabetic Kidney Disease
    Sandra Merscher-Gomez, Johanna Guzman, Christopher E. Pedigo, Markku Lehto, Robier Aguillon-Prada, Armando Mendez, Mariann I. Lassenius, Carol Forsblom, TaeHyun Yoo, Rodrigo Villarreal, Dony Maiguel, Kevin Johnson, Ronald Goldberg, Viji Nair, Ann Randolph, Matthias Kretzler, Robert G. Nelson, George W. Burke, Per-Henrik Groop, Alessia Fornoni and the FinnDiane Study Group
    Diabetes 2013 Nov; 62 (11): 3817-3827. https://doi.org/10.2337/db13-0399
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    Reversal of Neuropathic Pain in Diabetes by Targeting Glycosylation of Cav3.2 T-Type Calcium Channels
    Peihan Orestes, Hari Prasad Osuru, William E. McIntire, Megan O. Jacus, Reza Salajegheh, Miljen M. Jagodic, WonJoo Choe, JeongHan Lee, Sang-Soo Lee, Kirstin E. Rose, Nathan Poiro, Michael R. DiGruccio, Katiresan Krishnan, Douglas F. Covey, Jung-Ha Lee, Paula Q. Barrett, Vesna Jevtovic-Todorovic and Slobodan M. Todorovic
    Diabetes 2013 Nov; 62 (11): 3828-3838. https://doi.org/10.2337/db13-0813
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    Copper Transporter ATP7A Protects Against Endothelial Dysfunction in Type 1 Diabetic Mice by Regulating Extracellular Superoxide Dismutase
    Varadarajan Sudhahar, Norifumi Urao, Jin Oshikawa, Ronald D. McKinney, Roxana M. Llanos, Julian F.B. Mercer, Masuko Ushio-Fukai and Tohru Fukai
    Diabetes 2013 Nov; 62 (11): 3839-3850. https://doi.org/10.2337/db12-1228
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    C-Peptide Activates AMPKα and Prevents ROS-Mediated Mitochondrial Fission and Endothelial Apoptosis in Diabetes
    Mahendra Prasad Bhatt, Young-Cheol Lim, Young-Myeong Kim and Kwon-Soo Ha
    Diabetes 2013 Nov; 62 (11): 3851-3862. https://doi.org/10.2337/db13-0039
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    VEGF Secreted by Hypoxic Müller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy
    Murilo Rodrigues, Xiaoban Xin, Kathleen Jee, Savalan Babapoor-Farrokhran, Fabiana Kashiwabuchi, Tao Ma, Imran Bhutto, Syed Junaid Hassan, Yassine Daoud, David Baranano, Sharon Solomon, Gerard Lutty, Gregg L. Semenza, Silvia Montaner and Akrit Sodhi
    Diabetes 2013 Nov; 62 (11): 3863-3873. https://doi.org/10.2337/db13-0014
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    Inhibition of Src Kinase Blocks High Glucose–Induced EGFR Transactivation and Collagen Synthesis in Mesangial Cells and Prevents Diabetic Nephropathy in Mice
    Kanta Taniguchi, Ling Xia, Howard J. Goldberg, Ken W.K. Lee, Anu Shah, Laura Stavar, Elodie A.Y. Masson, Abdul Momen, Eric A. Shikatani, Rohan John, Mansoor Husain and I. George Fantus
    Diabetes 2013 Nov; 62 (11): 3874-3886. https://doi.org/10.2337/db12-1010
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    Myocardial Loss of IRS1 and IRS2 Causes Heart Failure and Is Controlled by p38α MAPK During Insulin Resistance
    Yajuan Qi, Zihui Xu, Qinglei Zhu, Candice Thomas, Rajesh Kumar, Hao Feng, David E. Dostal, Morris F. White, Kenneth M. Baker and Shaodong Guo
    Diabetes 2013 Nov; 62 (11): 3887-3900. https://doi.org/10.2337/db13-0095
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Pharmacology and Therapeutics

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    Teplizumab Preserves C-Peptide in Recent-Onset Type 1 DiabetesTwo-Year Results From the Randomized, Placebo-Controlled Protégé Trial
    William Hagopian, Robert J. Ferry, Nicole Sherry, David Carlin, Ezio Bonvini, Syd Johnson, Kathryn E. Stein, Scott Koenig, Anastasia G. Daifotis, Kevan C. Herold, Johnny Ludvigsson and for the Protégé Trial Investigators
    Diabetes 2013 Nov; 62 (11): 3901-3908. https://doi.org/10.2337/db13-0236
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    Molecular Mechanism of Sulphonylurea Block of KATP Channels Carrying Mutations That Impair ATP Inhibition and Cause Neonatal Diabetes
    Peter Proks, Heidi de Wet and Frances M. Ashcroft
    Diabetes 2013 Nov; 62 (11): 3909-3919. https://doi.org/10.2337/db13-0531
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    Prevention of Diabetes With Pioglitazone in ACT NOWPhysiologic Correlates
    Ralph A. DeFronzo, Devjit Tripathy, Dawn C. Schwenke, MaryAnn Banerji, George A. Bray, Thomas A. Buchanan, Stephen C. Clement, Amalia Gastaldelli, Robert R. Henry, Abbas E. Kitabchi, Sunder Mudaliar, Robert E. Ratner, Frankie B. Stentz, Nicolas Musi, Peter D. Reaven and for the ACT NOW Study
    Diabetes 2013 Nov; 62 (11): 3920-3926. https://doi.org/10.2337/db13-0265
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    Rhein Protects Pancreatic β-Cells From Dynamin-Related Protein-1–Mediated Mitochondrial Fission and Cell Apoptosis Under Hyperglycemia
    Jing Liu, Zhaohong Chen, Yujing Zhang, Mingchao Zhang, Xiaodong Zhu, Yun Fan, Shaolin Shi, Ke Zen and Zhihong Liu
    Diabetes 2013 Nov; 62 (11): 3927-3935. https://doi.org/10.2337/db13-0251
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Genetics/Genomes/Proteomics/Metabolomics

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    A New Strategy for Early Diagnosis of Type 2 Diabetes by Standard-Free, Label-Free LC-MS/MS Quantification of Glycated Peptides
    Mei Zhang, Wei Xu and Yulin Deng
    Diabetes 2013 Nov; 62 (11): 3936-3942. https://doi.org/10.2337/db13-0347
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    Autosomal Dominant Diabetes Arising From a Wolfram Syndrome 1 Mutation
    Lori L. Bonnycastle, Peter S. Chines, Takashi Hara, Jeroen R. Huyghe, Amy J. Swift, Pirkko Heikinheimo, Jana Mahadevan, Sirkku Peltonen, Hanna Huopio, Pirjo Nuutila, Narisu Narisu, Rachel L. Goldfeder, Michael L. Stitzel, Simin Lu, Michael Boehnke, Fumihiko Urano, Francis S. Collins and Markku Laakso
    Diabetes 2013 Nov; 62 (11): 3943-3950. https://doi.org/10.2337/db13-0571
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    Decreased Cord-Blood Phospholipids in Young Age–at–Onset Type 1 Diabetes
    Daria La Torre, Tuulikki Seppänen-Laakso, Helena E. Larsson, Tuulia Hyötyläinen, Sten A. Ivarsson, Åke Lernmark, Matej Orešič and and the DiPiS Study Group
    Diabetes 2013 Nov; 62 (11): 3951-3956. https://doi.org/10.2337/db13-0215
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Issues and Events

  • Open Access
    Issues and Events
    Diabetes 2013 Nov; 62 (11): 3957. https://doi.org/10.2337/db13-ie11
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Diabetes Digests

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    Highlights From the Latest in Diabetes Research
    Diabetes 2013 Nov; 62 (11): 3958-3959. https://doi.org/10.2337/db13-dd11
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Diabetes: 62 (11)

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November 2013, 62(11)
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