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Table of Contents

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January 01 2015; volume 64 issue 1

In This Issue

  • Open Access
    In This Issue of Diabetes
    Diabetes 2015 Jan; 64 (1): 1-2. https://doi.org/10.2337/db15-ti01
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Commentaries

  • Open Access
    Mineralocorticoid Receptors: An Appealing Target to Treat Coronary Microvascular Dysfunction in Diabetes
    Shawn B. Bender, Guanghong Jia and James R. Sowers
    Diabetes 2015 Jan; 64 (1): 3-5. https://doi.org/10.2337/db14-1425
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  • Open Access
    Glucose-Dependent Foxo1 Switch in Healing Wounds: A Shred of Hope for Diabetic Ulcers?
    Sigal Shaklai, Gabi Shefer and Naftali Stern
    Diabetes 2015 Jan; 64 (1): 6-8. https://doi.org/10.2337/db14-1440
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  • Open Access
    Hidden Complexities in the Measurement of Fructosyl-Lysine and Advanced Glycation End Products for Risk Prediction of Vascular Complications of Diabetes
    Naila Rabbani and Paul J. Thornalley
    Diabetes 2015 Jan; 64 (1): 9-11. https://doi.org/10.2337/db14-1516
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Metabolism

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    Deleted in Breast Cancer 1 Limits Adipose Tissue Fat Accumulation and Plays a Key Role in the Development of Metabolic Syndrome Phenotype
    Carlos Escande, Veronica Nin, Tamar Pirtskhalava, Claudia C.S. Chini, Tamar Tchkonia, James L. Kirkland and Eduardo N. Chini
    Diabetes 2015 Jan; 64 (1): 12-22. https://doi.org/10.2337/db14-0192
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    Compartmentalized Acyl-CoA Metabolism in Skeletal Muscle Regulates Systemic Glucose Homeostasis
    Lei O. Li, Trisha J. Grevengoed, David S. Paul, Olga Ilkayeva, Timothy R. Koves, Florencia Pascual, Christopher B. Newgard, Deborah M. Muoio and Rosalind A. Coleman
    Diabetes 2015 Jan; 64 (1): 23-35. https://doi.org/10.2337/db13-1070
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    Adiponectin Stimulates Autophagy and Reduces Oxidative Stress to Enhance Insulin Sensitivity During High-Fat Diet Feeding in Mice
    Ying Liu, Rengasamy Palanivel, Esther Rai, Min Park, Tim V. Gabor, Michael P. Scheid, Aimin Xu and Gary Sweeney
    Diabetes 2015 Jan; 64 (1): 36-48. https://doi.org/10.2337/db14-0267
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    Impaired Adiponectin Signaling Contributes to Disturbed Catabolism of Branched-Chain Amino Acids in Diabetic Mice
    Kun Lian, Chaosheng Du, Yi Liu, Di Zhu, Wenjun Yan, Haifeng Zhang, Zhibo Hong, Peilin Liu, Lijian Zhang, Haifeng Pei, Jinglong Zhang, Chao Gao, Chao Xin, Hexiang Cheng, Lize Xiong and Ling Tao
    Diabetes 2015 Jan; 64 (1): 49-59. https://doi.org/10.2337/db14-0312
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    PRMT3 Regulates Hepatic Lipogenesis Through Direct Interaction With LXRα
    Dong-il Kim, Min-jung Park, Seul-ki Lim, Jae-il Park, Kyung-chul Yoon, Ho-jae Han, Jan-Åke Gustafsson, Jae-hyang Lim and Soo-hyun Park
    Diabetes 2015 Jan; 64 (1): 60-71. https://doi.org/10.2337/db13-1394
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    Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes
    Mikkel Christensen, Salvatore Calanna, Alexander H. Sparre-Ulrich, Peter L. Kristensen, Mette M. Rosenkilde, Jens Faber, Francesco Purrello, Gerrit van Hall, Jens J. Holst, Tina Vilsbøll and Filip K. Knop
    Diabetes 2015 Jan; 64 (1): 72-78. https://doi.org/10.2337/db14-0440
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Signal Transduction

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    GLP-1 and Exendin-4 Transiently Enhance GABAA Receptor–Mediated Synaptic and Tonic Currents in Rat Hippocampal CA3 Pyramidal Neurons
    Sergiy V. Korol, Zhe Jin, Omar Babateen and Bryndis Birnir
    Diabetes 2015 Jan; 64 (1): 79-89. https://doi.org/10.2337/db14-0668
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Obesity Studies

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    Perforin Is a Novel Immune Regulator of Obesity-Related Insulin Resistance
    Xavier S. Revelo, Sue Tsai, Helena Lei, Helen Luck, Magar Ghazarian, Hubert Tsui, Sally Y. Shi, Stephanie Schroer, Cynthia T. Luk, Gloria H.Y. Lin, Tak W. Mak, Minna Woo, Shawn Winer and Daniel A. Winer
    Diabetes 2015 Jan; 64 (1): 90-103. https://doi.org/10.2337/db13-1524
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    Pancreastatin-Dependent Inflammatory Signaling Mediates Obesity-Induced Insulin Resistance
    Gautam K. Bandyopadhyay, Minh Lu, Ennio Avolio, Jawed A. Siddiqui, Jiaur R. Gayen, Joshua Wollam, Christine U. Vu, Nai-Wen Chi, Daniel T. O’Connor and Sushil K. Mahata
    Diabetes 2015 Jan; 64 (1): 104-116. https://doi.org/10.2337/db13-1747
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    Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Promotes Adipogenesis and Diet-Induced Obesity
    Min Park, Ja-Woon Yi, Eun-Mi Kim, Il-Joo Yoon, Eun-Hee Lee, Hwa-Youn Lee, Kon-Young Ji, Kwang-Ho Lee, Ji-Hun Jang, Seung-Su Oh, Chul-Ho Yun, Seung-Hyung Kim, Ki-Mo Lee, Mun-Gyu Song, Dong-Hoon Kim and Hyung-Sik Kang
    Diabetes 2015 Jan; 64 (1): 117-127. https://doi.org/10.2337/db13-1869
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    Adiponectin Induces A20 Expression in Adipose Tissue to Confer Metabolic Benefit
    Laura E. Hand, Paola Usan, Garth J.S. Cooper, Lance Y. Xu, Basil Ammori, Peter S. Cunningham, Reza Aghamohammadzadeh, Handrean Soran, Adam Greenstein, Andrew S.I. Loudon, David A. Bechtold and David W. Ray
    Diabetes 2015 Jan; 64 (1): 128-136. https://doi.org/10.2337/db13-1835
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    Distinct Networks of Leptin- and Insulin-Sensing Neurons Regulate Thermogenic Responses to Nutritional and Cold Challenges
    Angie C.N. Chong, Richard A. Greendyk and Lori M. Zeltser
    Diabetes 2015 Jan; 64 (1): 137-146. https://doi.org/10.2337/db14-0567
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Islet Studies

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    PTEN Deletion in Pancreatic α-Cells Protects Against High-Fat Diet–Induced Hyperglucagonemia and Insulin Resistance
    Linyuan Wang, Cynthia T. Luk, Erica P. Cai, Stephanie A. Schroer, Emma M. Allister, Sally Y. Shi, Michael B. Wheeler, Herbert Y. Gaisano and Minna Woo
    Diabetes 2015 Jan; 64 (1): 147-157. https://doi.org/10.2337/db13-1715
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Immunology and Transplantation

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    Interleukin-10+ Regulatory B Cells Arise Within Antigen-Experienced CD40+ B Cells to Maintain Tolerance to Islet Autoantigens
    Sonja Kleffel, Andrea Vergani, Sara Tezza, Moufida Ben Nasr, Monika A. Niewczas, Susan Wong, Roberto Bassi, Francesca D’Addio, Tobias Schatton, Reza Abdi, Mark Atkinson, Mohamed H. Sayegh, Li Wen, Clive H. Wasserfall, Kevin C. O’Connor and Paolo Fiorina
    Diabetes 2015 Jan; 64 (1): 158-171. https://doi.org/10.2337/db13-1639
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    Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+ T Cells Infiltrate Islets in Type 1 Diabetes
    Vimukthi Pathiraja, Janine P. Kuehlich, Peter D. Campbell, Balasubramanian Krishnamurthy, Thomas Loudovaris, P. Toby H. Coates, Thomas C. Brodnicki, Philip J. O’Connell, Katherine Kedzierska, Christine Rodda, Philip Bergman, Erin Hill, Anthony W. Purcell, Nadine L. Dudek, Helen E. Thomas, Thomas W.H. Kay and Stuart I. Mannering
    Diabetes 2015 Jan; 64 (1): 172-182. https://doi.org/10.2337/db14-0858
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Pathophysiology

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    Impaired Macromolecular Protein Pools in Fronto-Striato-Thalamic Circuits in Type 2 Diabetes Revealed by Magnetization Transfer Imaging
    Shaolin Yang, Olusola Ajilore, Minjie Wu, Melissa Lamar and Anand Kumar
    Diabetes 2015 Jan; 64 (1): 183-192. https://doi.org/10.2337/db14-0316
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    Loss-of-Function Mutations in ABCA1 and Enhanced β-Cell Secretory Capacity in Young Adults
    Michael R. Rickels, Eugen S. Goeser, Carissa Fuller, Christine Lord, Anne M. Bowler, Nicolai M. Doliba, Robert A. Hegele and Marina Cuchel
    Diabetes 2015 Jan; 64 (1): 193-199. https://doi.org/10.2337/db14-0436
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Complications

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    Deletion of Placental Growth Factor Prevents Diabetic Retinopathy and Is Associated With Akt Activation and HIF1α-VEGF Pathway Inhibition
    Hu Huang, Jianbo He, Da’Kuawn Johnson, Yanhong Wei, Ying Liu, Shuang Wang, Gerard A. Lutty, Elia J. Duh, Peter Carmeliet and Richard D. Semba
    Diabetes 2015 Jan; 64 (1): 200-212. https://doi.org/10.2337/db14-0016
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    High Tissue Glucose Alters Intersomitic Blood Vessels in Zebrafish via Methylglyoxal Targeting the VEGF Receptor Signaling Cascade
    Kristina Jörgens, Sandra J. Stoll, Jennifer Pohl, Thomas H. Fleming, Carsten Sticht, Peter P. Nawroth, Hans-Peter Hammes and Jens Kroll
    Diabetes 2015 Jan; 64 (1): 213-225. https://doi.org/10.2337/db14-0352
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    Perifornical Hypothalamic Orexin and Serotonin Modulate the Counterregulatory Response to Hypoglycemic and Glucoprivic Stimuli
    Oleg Otlivanchik, Christelle Le Foll and Barry E. Levin
    Diabetes 2015 Jan; 64 (1): 226-235. https://doi.org/10.2337/db14-0671
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    Mineralocorticoid Receptor Blockade Improves Coronary Microvascular Function in Individuals With Type 2 Diabetes
    Rajesh Garg, Ajay D. Rao, Maria Baimas-George, Shelley Hurwitz, Courtney Foster, Ravi V. Shah, Michael Jerosch-Herold, Raymond Y. Kwong, Marcelo F. Di Carli and Gail K. Adler
    Diabetes 2015 Jan; 64 (1): 236-242. https://doi.org/10.2337/db14-0670
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    Foxo1 Inhibits Diabetic Mucosal Wound Healing but Enhances Healing of Normoglycemic Wounds
    Fanxing Xu, Badr Othman, Jason Lim, Angelika Batres, Bhaskar Ponugoti, Chenying Zhang, Leah Yi, Jian Liu, Chen Tian, Alhassan Hameedaldeen, Sarah Alsadun, Rohinton Tarapore and Dana T. Graves
    Diabetes 2015 Jan; 64 (1): 243-256. https://doi.org/10.2337/db14-0589
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    Plasma Advanced Glycation End Products Are Associated With Incident Cardiovascular Events in Individuals With Type 2 Diabetes: A Case-Cohort Study With a Median Follow-up of 10 Years (EPIC-NL)
    Nordin M.J. Hanssen, Joline W.J. Beulens, Susan van Dieren, Jean L.J.M. Scheijen, Daphne L. van der A, Annemieke M.W. Spijkerman, Yvonne T. van der Schouw, Coen D.A. Stehouwer and Casper G. Schalkwijk
    Diabetes 2015 Jan; 64 (1): 257-265. https://doi.org/10.2337/db13-1864
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    Skin Advanced Glycation End Products Glucosepane and Methylglyoxal Hydroimidazolone Are Independently Associated With Long-term Microvascular Complication Progression of Type 1 Diabetes
    Saul Genuth, Wanjie Sun, Patricia Cleary, Xiaoyu Gao, David R. Sell, John Lachin, The DCCT/EDIC Research Group and Vincent M. Monnier
    Diabetes 2015 Jan; 64 (1): 266-278. https://doi.org/10.2337/db14-0215
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    Type 2 Diabetes, Skin Autofluorescence, and Brain Atrophy
    Chris Moran, Gerald Münch, Josephine M. Forbes, Richard Beare, Leigh Blizzard, Alison J. Venn, Thanh G. Phan, Jian Chen and Velandai Srikanth
    Diabetes 2015 Jan; 64 (1): 279-283. https://doi.org/10.2337/db14-0506
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Pharmacology and Therapeutics

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    Metformin Supports the Antidiabetic Effect of a Sodium Glucose Cotransporter 2 Inhibitor by Suppressing Endogenous Glucose Production in Diabetic Mice
    Susanne Neschen, Markus Scheerer, Anett Seelig, Peter Huypens, Jürgen Schultheiss, Moya Wu, Wolfgang Wurst, Birgit Rathkolb, Karsten Suhre, Eckhard Wolf, Johannes Beckers and Martin Hrabé de Angelis
    Diabetes 2015 Jan; 64 (1): 284-290. https://doi.org/10.2337/db14-0393
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Genetics/Genomes/Proteomics/Metabolomics

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    Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians
    Joo-Yeon Hwang, Xueling Sim, Ying Wu, Jun Liang, Yasuharu Tabara, Cheng Hu, Kazuo Hara, Claudia H.T. Tam, Qiuyin Cai, Qi Zhao, Sunha Jee, Fumihiko Takeuchi, Min Jin Go, Rick Twee Hee Ong, Takayoshi Ohkubo, Young Jin Kim, Rong Zhang, Toshimasa Yamauchi, Wing Yee So, Jirong Long, Dongfeng Gu, Nanette R. Lee, Soriul Kim, Tomohiro Katsuya, Ji Hee Oh, Jianjun Liu, Satoshi Umemura, Yeon-Jung Kim, Feng Jiang, Shiro Maeda, Juliana C.N. Chan, Wei Lu, James E. Hixson, Linda S. Adair, Keum Ji Jung, Toru Nabika, Jae-Bum Bae, Mi Hee Lee, Mark Seielstad, Terri L. Young, Yik Ying Teo, Yoshikuni Kita, Naoyuki Takashima, Haruhiko Osawa, So-Hyun Lee, Min-Ho Shin, Dong Hoon Shin, Bo Youl Choi, Jiajun Shi, Yu-Tang Gao, Yong-Bing Xiang, Wei Zheng, Norihiro Kato, Miwuk Yoon, Jiang He, Xiao Ou Shu, Ronald C.W. Ma, Takashi Kadowaki, Weiping Jia, Tetsuro Miki, Lu Qi, E Shyong Tai, Karen L. Mohlke, Bok-Ghee Han, Yoon Shin Cho and Bong-Jo Kim
    Diabetes 2015 Jan; 64 (1): 291-298. https://doi.org/10.2337/db14-0563
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    Clinical and Molecular Characterization of a Novel PLIN1 Frameshift Mutation Identified in Patients With Familial Partial Lipodystrophy
    Kristina Kozusko, Venessa H.M. Tsang, William Bottomley, Yoon-Hi Cho, Sheetal Gandotra, Michael Mimmack, Koini Lim, Iona Isaac, Satish Patel, Vladimir Saudek, Stephen O’Rahilly, Shubha Srinivasan, Jerry R. Greenfield, Ines Barroso, Lesley V. Campbell and David B. Savage
    Diabetes 2015 Jan; 64 (1): 299-310. https://doi.org/10.2337/db14-0104
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Statement of Principle

  • Open Access
    Statement of Principle
    Diabetes 2015 Jan; 64 (1): 311. https://doi.org/10.2337/db14-sp01
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Erratum

  • Open Access
    Bimodal Effect on Pancreatic β-Cells of Secretory Products From Normal or Insulin-Resistant Human Skeletal Muscle. Diabetes 2011;60:1111–1121
    Karim Bouzakri, Peter Plomgaard, Thierry Berney, Marc Y. Donath, Bente Karlund Pedersen and Philippe A. Halban
    Diabetes 2015 Jan; 64 (1): 312. https://doi.org/10.2337/db15-er01a
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Issues and Events

  • Open Access
    Issues and Events
    Diabetes 2015 Jan; 64 (1): 313. https://doi.org/10.2337/db15-ie01
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Diabetes: 64 (1)

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January 2015, 64(1)
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