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Pharmacology and Therapeutics

Lowering Plasma 1-Deoxysphingolipids Improves Neuropathy in Diabetic Rats

  1. Alaa Othman1,2,3,
  2. Roberto Bianchi4,
  3. Irina Alecu1,2,
  4. Yu Wei1,
  5. Carla Porretta-Serapiglia4,
  6. Raffaella Lombardi4,
  7. Alessia Chiorazzi5,
  8. Cristina Meregalli5,
  9. Norberto Oggioni5,
  10. Guido Cavaletti5,
  11. Giuseppe Lauria4,
  12. Arnold von Eckardstein1,2,3 and
  13. Thorsten Hornemann1,2,3⇑
  1. 1Institute for Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland
  2. 2Centre for Integrative Human Physiology, University of Zurich, Zurich, Switzerland
  3. 3Competence Centre for Systems Physiology and Metabolic Diseases, Zurich, Switzerland
  4. 4Neuroalgology and Headache Unit, IRCCS Foundation, Carlo Besta Neurological Institute, Milan, Italy
  5. 5Experimental Neurology Unit and Milan Center for Neuroscience, Department of Surgery and Translational Medicine, University of Milan-Bicocca, Milan, Italy
  1. Corresponding author: Thorsten Hornemann, thorsten.hornemann{at}usz.ch.
  1. A.O. and R.B. contributed equally to this study.

Diabetes 2015 Mar; 64(3): 1035-1045. https://doi.org/10.2337/db14-1325
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Article Information

vol. 64 no. 3 1035-1045
DOI 
https://doi.org/10.2337/db14-1325
PubMed 
25277395

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • Received August 27, 2014
  • Accepted September 22, 2014
  • Published in print February 24, 2015.
  • Published online ahead of print October 2, 2014.

Article Versions

  • Previous version (October 2, 2014 - 06:14).
  • Previous version (October 3, 2014 - 06:57).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

Author Information

  1. Alaa Othman1,2,3,
  2. Roberto Bianchi4,
  3. Irina Alecu1,2,
  4. Yu Wei1,
  5. Carla Porretta-Serapiglia4,
  6. Raffaella Lombardi4,
  7. Alessia Chiorazzi5,
  8. Cristina Meregalli5,
  9. Norberto Oggioni5,
  10. Guido Cavaletti5,
  11. Giuseppe Lauria4,
  12. Arnold von Eckardstein1,2,3 and
  13. Thorsten Hornemann1,2,3⇑
  1. 1Institute for Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland
  2. 2Centre for Integrative Human Physiology, University of Zurich, Zurich, Switzerland
  3. 3Competence Centre for Systems Physiology and Metabolic Diseases, Zurich, Switzerland
  4. 4Neuroalgology and Headache Unit, IRCCS Foundation, Carlo Besta Neurological Institute, Milan, Italy
  5. 5Experimental Neurology Unit and Milan Center for Neuroscience, Department of Surgery and Translational Medicine, University of Milan-Bicocca, Milan, Italy
  1. Corresponding author: Thorsten Hornemann, thorsten.hornemann{at}usz.ch.
  1. A.O. and R.B. contributed equally to this study.

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Lowering Plasma 1-Deoxysphingolipids Improves Neuropathy in Diabetic Rats
Alaa Othman, Roberto Bianchi, Irina Alecu, Yu Wei, Carla Porretta-Serapiglia, Raffaella Lombardi, Alessia Chiorazzi, Cristina Meregalli, Norberto Oggioni, Guido Cavaletti, Giuseppe Lauria, Arnold von Eckardstein, Thorsten Hornemann
Diabetes Mar 2015, 64 (3) 1035-1045; DOI: 10.2337/db14-1325

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Lowering Plasma 1-Deoxysphingolipids Improves Neuropathy in Diabetic Rats
Alaa Othman, Roberto Bianchi, Irina Alecu, Yu Wei, Carla Porretta-Serapiglia, Raffaella Lombardi, Alessia Chiorazzi, Cristina Meregalli, Norberto Oggioni, Guido Cavaletti, Giuseppe Lauria, Arnold von Eckardstein, Thorsten Hornemann
Diabetes Mar 2015, 64 (3) 1035-1045; DOI: 10.2337/db14-1325
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