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Genetics/Genomes/Proteomics/Metabolomics

Sixty-Five Common Genetic Variants and Prediction of Type 2 Diabetes

  1. Philippa J. Talmud1⇑,
  2. Jackie A. Cooper1,
  3. Richard W. Morris2,
  4. Frank Dudbridge3,
  5. Tina Shah4,
  6. Jorgen Engmann4,
  7. Caroline Dale3,
  8. Jon White5,
  9. Stela McLachlan6,
  10. Delilah Zabaneh5,
  11. Andrew Wong7,
  12. Ken K. Ong7,8,
  13. Tom Gaunt9,10,
  14. Michael V. Holmes4,11,
  15. Debbie A. Lawlor9,10,
  16. Marcus Richards7,
  17. Rebecca Hardy7,
  18. Diana Kuh7,
  19. Nicholas Wareham8,
  20. Claudia Langenberg4,8,
  21. Yoav Ben-Shlomo10,
  22. S. Goya Wannamethee2,
  23. Mark W.J. Strachan12,
  24. Meena Kumari4,
  25. John C. Whittaker13,
  26. Fotios Drenos1,10,
  27. Mika Kivimaki4,
  28. Aroon D. Hingorani4,14,
  29. Jacqueline F. Price6 and
  30. Steve E. Humphries1
  31. on behalf of the UCLEB Consortium
  1. 1Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, U.K.
  2. 2Department of Primary Care and Population Health, University College London, Royal Free Campus, London, U.K.
  3. 3Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, U.K.
  4. 4Department of Epidemiology and Public Health, University College London Institute of Epidemiology and Health Care, University College London, London, U.K.
  5. 5University College London Genetics Institute, Department of Genetics, Environment and Evolution, London, U.K.
  6. 6Centre for Population Health Sciences, University of Edinburgh, Edinburgh, U.K.
  7. 7Medical Research Council Unit for Lifelong Health and Ageing at University College London, London, U.K.
  8. 8Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, U.K.
  9. 9School of Social and Community Medicine, University of Bristol, Bristol, U.K.
  10. 10Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, U.K.
  11. 11Division of Transplant Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
  12. 12Metabolic Unit, Western General Hospital, Edinburgh, U.K.
  13. 13Genetics Division, Research and Development, GlaxoSmithKline, Harlow, U.K.
  14. 14Centre for Clinical Pharmacology, University College London, London, U.K.
  1. Corresponding author: Philippa J. Talmud, p.talmud{at}ucl.ac.uk.
Diabetes 2015 May; 64(5): 1830-1840. https://doi.org/10.2337/db14-1504
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Article Information

vol. 64 no. 5 1830-1840
DOI 
https://doi.org/10.2337/db14-1504
PubMed 
25475436

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • Received October 9, 2014
  • Accepted November 27, 2014
  • Published in print April 23, 2015.
  • Published online ahead of print December 4, 2014.

Article Versions

  • Previous version (December 4, 2014 - 13:59).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

Author Information

  1. Philippa J. Talmud1⇑,
  2. Jackie A. Cooper1,
  3. Richard W. Morris2,
  4. Frank Dudbridge3,
  5. Tina Shah4,
  6. Jorgen Engmann4,
  7. Caroline Dale3,
  8. Jon White5,
  9. Stela McLachlan6,
  10. Delilah Zabaneh5,
  11. Andrew Wong7,
  12. Ken K. Ong7,8,
  13. Tom Gaunt9,10,
  14. Michael V. Holmes4,11,
  15. Debbie A. Lawlor9,10,
  16. Marcus Richards7,
  17. Rebecca Hardy7,
  18. Diana Kuh7,
  19. Nicholas Wareham8,
  20. Claudia Langenberg4,8,
  21. Yoav Ben-Shlomo10,
  22. S. Goya Wannamethee2,
  23. Mark W.J. Strachan12,
  24. Meena Kumari4,
  25. John C. Whittaker13,
  26. Fotios Drenos1,10,
  27. Mika Kivimaki4,
  28. Aroon D. Hingorani4,14,
  29. Jacqueline F. Price6 and
  30. Steve E. Humphries1
  31. on behalf of the UCLEB Consortium
  1. 1Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, U.K.
  2. 2Department of Primary Care and Population Health, University College London, Royal Free Campus, London, U.K.
  3. 3Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, U.K.
  4. 4Department of Epidemiology and Public Health, University College London Institute of Epidemiology and Health Care, University College London, London, U.K.
  5. 5University College London Genetics Institute, Department of Genetics, Environment and Evolution, London, U.K.
  6. 6Centre for Population Health Sciences, University of Edinburgh, Edinburgh, U.K.
  7. 7Medical Research Council Unit for Lifelong Health and Ageing at University College London, London, U.K.
  8. 8Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, U.K.
  9. 9School of Social and Community Medicine, University of Bristol, Bristol, U.K.
  10. 10Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, U.K.
  11. 11Division of Transplant Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
  12. 12Metabolic Unit, Western General Hospital, Edinburgh, U.K.
  13. 13Genetics Division, Research and Development, GlaxoSmithKline, Harlow, U.K.
  14. 14Centre for Clinical Pharmacology, University College London, London, U.K.
  1. Corresponding author: Philippa J. Talmud, p.talmud{at}ucl.ac.uk.
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Sixty-Five Common Genetic Variants and Prediction of Type 2 Diabetes
Philippa J. Talmud, Jackie A. Cooper, Richard W. Morris, Frank Dudbridge, Tina Shah, Jorgen Engmann, Caroline Dale, Jon White, Stela McLachlan, Delilah Zabaneh, Andrew Wong, Ken K. Ong, Tom Gaunt, Michael V. Holmes, Debbie A. Lawlor, Marcus Richards, Rebecca Hardy, Diana Kuh, Nicholas Wareham, Claudia Langenberg, Yoav Ben-Shlomo, S. Goya Wannamethee, Mark W.J. Strachan, Meena Kumari, John C. Whittaker, Fotios Drenos, Mika Kivimaki, Aroon D. Hingorani, Jacqueline F. Price, Steve E. Humphries
Diabetes May 2015, 64 (5) 1830-1840; DOI: 10.2337/db14-1504

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Sixty-Five Common Genetic Variants and Prediction of Type 2 Diabetes
Philippa J. Talmud, Jackie A. Cooper, Richard W. Morris, Frank Dudbridge, Tina Shah, Jorgen Engmann, Caroline Dale, Jon White, Stela McLachlan, Delilah Zabaneh, Andrew Wong, Ken K. Ong, Tom Gaunt, Michael V. Holmes, Debbie A. Lawlor, Marcus Richards, Rebecca Hardy, Diana Kuh, Nicholas Wareham, Claudia Langenberg, Yoav Ben-Shlomo, S. Goya Wannamethee, Mark W.J. Strachan, Meena Kumari, John C. Whittaker, Fotios Drenos, Mika Kivimaki, Aroon D. Hingorani, Jacqueline F. Price, Steve E. Humphries
Diabetes May 2015, 64 (5) 1830-1840; DOI: 10.2337/db14-1504
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