The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History on the Progression From Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report

Jeffrey P. Krischer; Xiang Liu; Åke Lernmark; William A. Hagopian; Marian J. Rewers; Jin-Xiong She; Jorma Toppari; Anette-G. Ziegler; Beena Akolkar

doi:10.2337/db17-0261

Genetics/Genomes/Proteomics/Metabolomics

The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History on the Progression From Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report

Jeffrey P. Krischer¹ ⇑,
Xiang Liu¹,
Åke Lernmark²,
William A. Hagopian³,
Marian J. Rewers⁴,
Jin-Xiong She⁵,
Jorma Toppari⁶,⁷,
Anette-G. Ziegler⁸ and
Beena Akolkar⁹
on behalf of the TEDDY Study Group*

¹Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL
²Department of Clinical Sciences, Lund University Clinical Research Center, Skåne University Hospital, Malmö, Sweden
³Pacific Northwest Diabetes Research Institute, Seattle, WA
⁴Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO
⁵Center for Biotechnology and Genomic Medicine, Augusta University, Augusta, GA
⁶Department of Pediatrics, Turku University Hospital, Turku, Finland
⁷Department of Physiology, Institute of Biomedicine, University of Turku, Turku, Finland
⁸Institute of Diabetes Research, Helmholtz Zentrum München; Klinikum rechts der Isar, Technische Universität München; and Forschergruppe Diabetes e.V., Neuherberg, Germany
⁹National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD

Corresponding author: Jeffrey P. Krischer, jeffrey.krischer{at}epi.usf.edu.

Diabetes 2017 Dec; 66(12): 3122-3129. https://doi.org/10.2337/db17-0261

Article Information

vol. 66 no. 12 3122-3129

DOI

https://doi.org/10.2337/db17-0261

PubMed

28903990

Published By

American Diabetes Association

Print ISSN

0012-1797

Online ISSN

1939-327X

History

Received February 28, 2017
Accepted September 7, 2017
Published in print November 21, 2017.
Published online ahead of print September 13, 2017.

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© 2017 by the American Diabetes Association. http://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

Author Information

Jeffrey P. Krischer¹ ⇑,
Xiang Liu¹,
Åke Lernmark²,
William A. Hagopian³,
Marian J. Rewers⁴,
Jin-Xiong She⁵,
Jorma Toppari⁶,⁷,
Anette-G. Ziegler⁸ and
Beena Akolkar⁹
on behalf of the TEDDY Study Group*

¹Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL
²Department of Clinical Sciences, Lund University Clinical Research Center, Skåne University Hospital, Malmö, Sweden
³Pacific Northwest Diabetes Research Institute, Seattle, WA
⁴Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO
⁵Center for Biotechnology and Genomic Medicine, Augusta University, Augusta, GA
⁶Department of Pediatrics, Turku University Hospital, Turku, Finland
⁷Department of Physiology, Institute of Biomedicine, University of Turku, Turku, Finland
⁸Institute of Diabetes Research, Helmholtz Zentrum München; Klinikum rechts der Isar, Technische Universität München; and Forschergruppe Diabetes e.V., Neuherberg, Germany
⁹National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD

Corresponding author: Jeffrey P. Krischer, jeffrey.krischer{at}epi.usf.edu.

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