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Perspectives in Diabetes

Proximal Tubulopathy: Prime Mover and Key Therapeutic Target in Diabetic Kidney Disease

  1. Richard E. Gilbert⇑
  1. Keenan Research Centre for Biomedical Science and Li Ka Shing Knowledge Institute of St. Michael’s Hospital, Toronto, Canada
  1. Corresponding author: Richard E. Gilbert, richard.gilbert{at}utoronto.ca.
Diabetes 2017 Apr; 66(4): 791-800. https://doi.org/10.2337/db16-0796
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Article Information

vol. 66 no. 4 791-800
DOI 
https://doi.org/10.2337/db16-0796
PubMed 
28325740

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • Received June 30, 2016
  • Accepted January 2, 2017
  • Published in print March 21, 2017.

Copyright & Usage 
© 2017 by the American Diabetes Association. http://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

Author Information

  1. Richard E. Gilbert⇑
  1. Keenan Research Centre for Biomedical Science and Li Ka Shing Knowledge Institute of St. Michael’s Hospital, Toronto, Canada
  1. Corresponding author: Richard E. Gilbert, richard.gilbert{at}utoronto.ca.
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Diabetes: 66 (4)

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April 2017, 66(4)
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Proximal Tubulopathy: Prime Mover and Key Therapeutic Target in Diabetic Kidney Disease
Richard E. Gilbert
Diabetes Apr 2017, 66 (4) 791-800; DOI: 10.2337/db16-0796

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Proximal Tubulopathy: Prime Mover and Key Therapeutic Target in Diabetic Kidney Disease
Richard E. Gilbert
Diabetes Apr 2017, 66 (4) 791-800; DOI: 10.2337/db16-0796
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  • Article
    • Abstract
    • Introduction
    • Normal and Disordered Structure
    • Primary Tubulopathy Induces Secondary Glomerular Disease
    • The Contiuum of Acute and Chronic Kidney Disease
    • Biomarkers of Proximal Tubular Injury
    • Tubular Hypoxia: a Driving Force in Diabetic Kidney Disease
    • Nonhypoxia-Related Proximal Tubular Mechanisms
    • Proximal Tubule–Targeted Therapeutics
    • Conclusion
    • Article Information
    • References
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  • Info & Metrics
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  • Emerging Role of Bone Morphogenetic Protein 4 in Metabolic Disorders
  • Deciphering the Complex Communication Networks That Orchestrate Pancreatic Islet Function
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