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Islet Studies

Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction

  1. Jianyang Fu1,2,
  2. Xiaoqing Dai1,2,
  3. Gregory Plummer1,2,
  4. Kunimasa Suzuki1,2,
  5. Austin Bautista1,2,
  6. John M. Githaka3,
  7. Laura Senior1,2,
  8. Mette Jensen4,
  9. Dafna Greitzer-Antes5,
  10. Jocelyn E. Manning Fox1,2,
  11. Herbert Y. Gaisano5,
  12. Christopher B. Newgard4,
  13. Nicolas Touret3 and
  14. Patrick E. MacDonald1,2⇑
  1. 1Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
  2. 2Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada
  3. 3Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada
  4. 4Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Departments of Pharmacology & Cancer Biology and Medicine, Duke University, Durham, NC
  5. 5Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario, Canada
  1. Corresponding author: Patrick E. MacDonald, pmacdonald{at}ualberta.ca.
Diabetes 2017 Jul; 66(7): 1890-1900. https://doi.org/10.2337/db16-1170
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Article Information

vol. 66 no. 7 1890-1900
DOI 
https://doi.org/10.2337/db16-1170
PubMed 
28607108

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • Received September 26, 2016
  • Accepted April 15, 2017
  • Published in print June 21, 2017.
  • Published online ahead of print June 12, 2017.

Article Versions

  • Previous version (June 12, 2017 - 07:02).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2017 by the American Diabetes Association. http://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

Author Information

  1. Jianyang Fu1,2,
  2. Xiaoqing Dai1,2,
  3. Gregory Plummer1,2,
  4. Kunimasa Suzuki1,2,
  5. Austin Bautista1,2,
  6. John M. Githaka3,
  7. Laura Senior1,2,
  8. Mette Jensen4,
  9. Dafna Greitzer-Antes5,
  10. Jocelyn E. Manning Fox1,2,
  11. Herbert Y. Gaisano5,
  12. Christopher B. Newgard4,
  13. Nicolas Touret3 and
  14. Patrick E. MacDonald1,2⇑
  1. 1Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
  2. 2Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada
  3. 3Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada
  4. 4Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Departments of Pharmacology & Cancer Biology and Medicine, Duke University, Durham, NC
  5. 5Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario, Canada
  1. Corresponding author: Patrick E. MacDonald, pmacdonald{at}ualberta.ca.
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Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction
Jianyang Fu, Xiaoqing Dai, Gregory Plummer, Kunimasa Suzuki, Austin Bautista, John M. Githaka, Laura Senior, Mette Jensen, Dafna Greitzer-Antes, Jocelyn E. Manning Fox, Herbert Y. Gaisano, Christopher B. Newgard, Nicolas Touret, Patrick E. MacDonald
Diabetes Jul 2017, 66 (7) 1890-1900; DOI: 10.2337/db16-1170

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Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction
Jianyang Fu, Xiaoqing Dai, Gregory Plummer, Kunimasa Suzuki, Austin Bautista, John M. Githaka, Laura Senior, Mette Jensen, Dafna Greitzer-Antes, Jocelyn E. Manning Fox, Herbert Y. Gaisano, Christopher B. Newgard, Nicolas Touret, Patrick E. MacDonald
Diabetes Jul 2017, 66 (7) 1890-1900; DOI: 10.2337/db16-1170
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