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Table of Contents

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August 01 2017; volume 66 issue 8

In This Issue

  • Open Access
    In This Issue of Diabetes
    Diabetes 2017 Aug; 66 (8): 2061-2062. https://doi.org/10.2337/db17-ti08
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Commentaries

  • Open Access
    Species-Dependent Mechanisms Regulating Glucose-Dependent GLP-1 Secretion?
    Patricia L. Brubaker
    Diabetes 2017 Aug; 66 (8): 2063-2065. https://doi.org/10.2337/dbi17-0020
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  • Open Access
    Bait and Trap: Enriching Autoreactive T Cells With β-Cell Antigen-Loading Biomaterial Scaffolds for Early Detection of Type 1 Diabetes
    Yong Fan
    Diabetes 2017 Aug; 66 (8): 2066-2068. https://doi.org/10.2337/dbi17-0019
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  • Open Access
    Some Doubts About the Mantra on the Deleterious Cardiovascular Effects of Sulfonylureas
    Vincenzo Trischitta and Sabrina Prudente
    Diabetes 2017 Aug; 66 (8): 2069-2071. https://doi.org/10.2337/dbi17-0023
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Metabolism

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    Mitochondrial-Targeted Catalase Protects Against High-Fat Diet–Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation
    Hui-Young Lee, Jae Sung Lee, Tiago Alves, Warren Ladiges, Peter S. Rabinovitch, Michael J. Jurczak, Cheol Soo Choi, Gerald I. Shulman and Varman T. Samuel
    Diabetes 2017 Aug; 66 (8): 2072-2081. https://doi.org/10.2337/db16-1334
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    Intramyocellular Ceramides: Subcellular Concentrations and Fractional De Novo Synthesis in Postabsorptive Humans
    Jin Ook Chung, Christina Koutsari, Agnieszka U. Blachnio-Zabielska, Kazanna C. Hames and Michael D. Jensen
    Diabetes 2017 Aug; 66 (8): 2082-2091. https://doi.org/10.2337/db17-0082
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    Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in db/db Mice
    Emi Ishida, Ja Young Kim-Muller and Domenico Accili
    Diabetes 2017 Aug; 66 (8): 2092-2101. https://doi.org/10.2337/db16-1213
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    Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity
    Jung Dae Kim, Chitoku Toda, Cristina M. Ramírez, Carlos Fernández-Hernando and Sabrina Diano
    Diabetes 2017 Aug; 66 (8): 2102-2111. https://doi.org/10.2337/db16-1558
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    Acyl-CoA Thioesterase 1 (ACOT1) Regulates PPARα to Couple Fatty Acid Flux With Oxidative Capacity During Fasting
    Mallory P. Franklin, Aishwarya Sathyanarayan and Douglas G. Mashek
    Diabetes 2017 Aug; 66 (8): 2112-2123. https://doi.org/10.2337/db16-1519
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    Maternal Exercise Improves Glucose Tolerance in Female Offspring
    Kristin I. Stanford, Hirokazu Takahashi, Kawai So, Ana Barbara Alves-Wagner, Noah B. Prince, Adam C. Lehnig, Kristen M. Getchell, Min-Young Lee, Michael F. Hirshman and Laurie J. Goodyear
    Diabetes 2017 Aug; 66 (8): 2124-2136. https://doi.org/10.2337/db17-0098
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    Cationic Polystyrene Resolves Nonalcoholic Steatohepatitis, Obesity, and Metabolic Disorders by Promoting Eubiosis of Gut Microbiota and Decreasing Endotoxemia
    Airu Zhu, Jingjing Chen, Pengfei Wu, Mei Luo, Yilan Zeng, Yong Liu, Han Zheng, Li Zhang, Zishou Chen, Qun Sun, Wenwen Li, Yixiang Duan, Danmei Su, Zhixiong Xiao, Zhongping Duan, Sujun Zheng, Li Bai, Xiaohui Zhang, Zhongyuan Ju, Yan Li, Richard Hu, Stephen J. Pandol and Yuan-Ping Han
    Diabetes 2017 Aug; 66 (8): 2137-2143. https://doi.org/10.2337/db17-0070
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Signal Transduction

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    Mechanisms Controlling Glucose-Induced GLP-1 Secretion in Human Small Intestine
    Emily W. Sun, Dayan de Fontgalland, Philippa Rabbitt, Paul Hollington, Luigi Sposato, Steven L. Due, David A. Wattchow, Christopher K. Rayner, Adam M. Deane, Richard L. Young and Damien J. Keating
    Diabetes 2017 Aug; 66 (8): 2144-2149. https://doi.org/10.2337/db17-0058
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Islet Studies

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    Overexpression of Kinase-Dead mTOR Impairs Glucose Homeostasis by Regulating Insulin Secretion and Not β-Cell Mass
    Emilyn U. Alejandro, Nadejda Bozadjieva, Manuel Blandino-Rosano, Michelle Ann Wasan, Lynda Elghazi, Suryakiran Vadrevu, Leslie Satin and Ernesto Bernal-Mizrachi
    Diabetes 2017 Aug; 66 (8): 2150-2162. https://doi.org/10.2337/db16-1349
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    Radiomanganese PET Detects Changes in Functional β-Cell Mass in Mouse Models of Diabetes
    Reinier Hernandez, Stephen A. Graves, Trillian Gregg, Halena R. VanDeusen, Rachel J. Fenske, Haley N. Wienkes, Christopher G. England, Hector F. Valdovinos, Justin J. Jeffery, Todd E. Barnhart, Gregory W. Severin, Robert J. Nickles, Michelle E. Kimple, Matthew J. Merrins and Weibo Cai
    Diabetes 2017 Aug; 66 (8): 2163-2174. https://doi.org/10.2337/db16-1285
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    Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca2+-Regulated Genes
    Jennifer S. Stancill, Jean-Philippe Cartailler, Hannah W. Clayton, James T. O’Connor, Matthew T. Dickerson, Prasanna K. Dadi, Anna B. Osipovich, David A. Jacobson and Mark A. Magnuson
    Diabetes 2017 Aug; 66 (8): 2175-2187. https://doi.org/10.2337/db16-1355
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    Temporal Transcriptomic and Proteomic Landscapes of Deteriorating Pancreatic Islets in Type 2 Diabetic Rats
    Junjie Hou, Zonghong Li, Wen Zhong, Qiang Hao, Lei Lei, Linlin Wang, Dongyu Zhao, Pingyong Xu, Yifa Zhou, You Wang and Tao Xu
    Diabetes 2017 Aug; 66 (8): 2188-2200. https://doi.org/10.2337/db16-1305
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    Neprilysin Is Required for Angiotensin-(1–7)’s Ability to Enhance Insulin Secretion via Its Proteolytic Activity to Generate Angiotensin-(1–2)
    Gurkirat S. Brar, Breanne M. Barrow, Matthew Watson, Ryan Griesbach, Edwina Choung, Andrew Welch, Bela Ruzsicska, Daniel P. Raleigh and Sakeneh Zraika
    Diabetes 2017 Aug; 66 (8): 2201-2212. https://doi.org/10.2337/db16-1318
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    SOX4 Allows Facultative β-Cell Proliferation Through Repression of Cdkn1a
    Eric E. Xu, Shugo Sasaki, Thilo Speckmann, Cuilan Nian and Francis C. Lynn
    Diabetes 2017 Aug; 66 (8): 2213-2219. https://doi.org/10.2337/db16-1074
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Immunology and Transplantation

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    In Vivo Enrichment of Diabetogenic T Cells
    Martin A. Thelin, Stephan Kissler, Frederic Vigneault, Alexander L. Watters, Des White, Sandeep T. Koshy, Sarah A. Vermillion, David J. Mooney, Thomas Serwold and Omar A. Ali
    Diabetes 2017 Aug; 66 (8): 2220-2229. https://doi.org/10.2337/db16-0946
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Pathophysiology

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    Glucagon-Like Peptide 1 Receptor Activation Augments Cardiac Output and Improves Cardiac Efficiency in Obese Swine After Myocardial Infarction
    Daniel J. Sassoon, Johnathan D. Tune, Kieren J. Mather, Jillian N. Noblet, Mackenzie A. Eagleson, Abass M. Conteh, Joshua T. Sturek and Adam G. Goodwill
    Diabetes 2017 Aug; 66 (8): 2230-2240. https://doi.org/10.2337/db16-1206
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    Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver
    Tomas Jelenik, Kirti Kaul, Gilles Séquaris, Ulrich Flögel, Esther Phielix, Jörg Kotzka, Birgit Knebel, Pia Fahlbusch, Tina Hörbelt, Stefan Lehr, Anna Lena Reinbeck, Dirk Müller-Wieland, Irene Esposito, Gerald I. Shulman, Julia Szendroedi and Michael Roden
    Diabetes 2017 Aug; 66 (8): 2241-2253. https://doi.org/10.2337/db16-1147
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Complications

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    Topical Erythropoietin Treatment Accelerates the Healing of Cutaneous Burn Wounds in Diabetic Pigs Through an Aquaporin-3–Dependent Mechanism
    Saher Hamed, Yehuda Ullmann, Dana Egozi, Aviad Keren, Essam Daod, Omer Anis, Hoda Kabha, Mark Belokopytov, Manal Ashkar, Rona Shofti, Asaph Zaretsky, Michal Schlesinger, Luc Teot and Paul Y. Liu
    Diabetes 2017 Aug; 66 (8): 2254-2265. https://doi.org/10.2337/db16-1205
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    Protective Effect of let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis
    Eoin Brennan, Bo Wang, Aaron McClelland, Muthukumar Mohan, Mariam Marai, Ophelie Beuscart, Sinda Derouiche, Stephen Gray, Raelene Pickering, Chris Tikellis, Monica de Gaetano, Mary Barry, Orina Belton, Syed Tasadaque Ali-Shah, Patrick Guiry, Karin A.M. Jandeleit-Dahm, Mark E. Cooper, Catherine Godson and Phillip Kantharidis
    Diabetes 2017 Aug; 66 (8): 2266-2277. https://doi.org/10.2337/db16-1405
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    Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease in Individuals With Type 1 Diabetes: A 12-Year Follow-up Study
    Nordin M.J. Hanssen, Jean L.J.M. Scheijen, Anders Jorsal, Hans-Henrik Parving, Lise Tarnow, Peter Rossing, Coen D.A. Stehouwer and Casper G. Schalkwijk
    Diabetes 2017 Aug; 66 (8): 2278-2283. https://doi.org/10.2337/db16-1578
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Genetics/Genomes/Proteomics/Metabolomics

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    A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians
    Paolo Piaggi, Ivica Masindova, Yunhua L. Muller, Josep Mercader, Gregory B. Wiessner, Peng Chen, SIGMA Type 2 Diabetes Consortium, Sayuko Kobes, Wen-Chi Hsueh, Milliejoan Mongalo, William C. Knowler, Jonathan Krakoff, Robert L. Hanson, Clifton Bogardus and Leslie J. Baier
    Diabetes 2017 Aug; 66 (8): 2284-2295. https://doi.org/10.2337/db16-1565
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    A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants
    Andrew R. Wood, Anna Jonsson, Anne U. Jackson, Nan Wang, Nienke van Leewen, Nicholette D. Palmer, Sayuko Kobes, Joris Deelen, Lorena Boquete-Vilarino, Jussi Paananen, Alena Stančáková, Dorret I. Boomsma, Eco J.C. de Geus, Elisabeth M.W. Eekhoff, Andreas Fritsche, Mark Kramer, Giel Nijpels, Annemarie Simonis-Bik, Timon W. van Haeften, Anubha Mahajan, Michael Boehnke, Richard N. Bergman, Jaakko Tuomilehto, Francis S. Collins, Karen L. Mohlke, Karina Banasik, Christopher J. Groves, Mark I. McCarthy, Diabetes Research on Patient Stratification (DIRECT), Ewan R. Pearson, Andrea Natali, Andrea Mari, Thomas A. Buchanan, Kent D. Taylor, Anny H. Xiang, Anette P. Gjesing, Niels Grarup, Hans Eiberg, Oluf Pedersen, Yii-Derr Chen, Markku Laakso, Jill M. Norris, Ulf Smith, Lynne E. Wagenknecht, Leslie Baier, Donald W. Bowden, Torben Hansen, Mark Walker, Richard M. Watanabe, Leen M. ‘t Hart, Robert L. Hanson and Timothy M. Frayling
    Diabetes 2017 Aug; 66 (8): 2296-2309. https://doi.org/10.2337/db16-1452
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    Genetic Variation at the Sulfonylurea Receptor, Type 2 Diabetes, and Coronary Heart Disease
    Connor A. Emdin, Derek Klarin, Pradeep Natarajan, CARDIOGRAM Exome Consortium, Jose C. Florez, Sekar Kathiresan and Amit V. Khera
    Diabetes 2017 Aug; 66 (8): 2310-2315. https://doi.org/10.2337/db17-0149
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    Recessively Inherited LRBA Mutations Cause Autoimmunity Presenting as Neonatal Diabetes
    Matthew B. Johnson, Elisa De Franco, Hana Lango Allen, Aisha Al Senani, Nancy Elbarbary, Zeynep Siklar, Merih Berberoglu, Zineb Imane, Alireza Haghighi, Zahra Razavi, Irfan Ullah, Saif Alyaarubi, Daphne Gardner, Ayla Güven, Sian Ellard, Andrew T. Hattersley and Sarah E. Flanagan
    Diabetes 2017 Aug; 66 (8): 2316-2322. https://doi.org/10.2337/db17-0040
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Issues and Events

  • Open Access
    Issues and Events
    Diabetes 2017 Aug; 66 (8): 2323. https://doi.org/10.2337/db17-ie08
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e-Letters: Comments and Responses

  • Open Access
    Comment on Muka et al. Associations of Steroid Sex Hormones and Sex Hormone–Binding Globulin With the Risk of Type 2 Diabetes in Women: A Population-Based Cohort Study and Meta-analysis. Diabetes 2017;66:577–586
    Ali Abbasi
    Diabetes 2017 Aug; 66 (8): e7. https://doi.org/10.2337/db17-0269
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Diabetes: 66 (8)

In this Issue

August 2017, 66(8)
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