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Islet Studies

Radiomanganese PET Detects Changes in Functional β-Cell Mass in Mouse Models of Diabetes

  1. Reinier Hernandez1,
  2. Stephen A. Graves1,
  3. Trillian Gregg2,3,
  4. Halena R. VanDeusen2,
  5. Rachel J. Fenske2,
  6. Haley N. Wienkes2,
  7. Christopher G. England1,
  8. Hector F. Valdovinos1,
  9. Justin J. Jeffery4,
  10. Todd E. Barnhart1,
  11. Gregory W. Severin5,6,
  12. Robert J. Nickles1,
  13. Michelle E. Kimple2,7,
  14. Matthew J. Merrins2,7,8⇑ and
  15. Weibo Cai1,4,9⇑
  1. 1Department of Medical Physics, University of Wisconsin-Madison, Madison, WI
  2. 2Department of Medicine, Division of Endocrinology, Diabetes & Metabolism, University of Wisconsin-Madison, Madison, WI
  3. 3Program in Biophysics, University of Wisconsin-Madison, Madison, WI
  4. 4Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI
  5. 5Center for Nuclear Technologies, Technical University of Denmark, Roskilde, Denmark
  6. 6Department of Chemistry, Michigan State University, East Lansing, MI
  7. 7William S. Middleton Memorial Veterans Hospital, Madison, WI
  8. 8Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI
  9. 9Department of Radiology, University of Wisconsin-Madison, Madison, WI
  1. Corresponding authors: Matthew J. Merrins, merrins{at}wisc.edu, and Weibo Cai, wcai{at}uwhealth.org.

  1. R.H. and S.A.G. contributed equally to this work.

Diabetes 2017 Aug; 66(8): 2163-2174. https://doi.org/10.2337/db16-1285

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Radiomanganese PET Detects Changes in Functional β-Cell Mass in Mouse Models of Diabetes
Reinier Hernandez, Stephen A. Graves, Trillian Gregg, Halena R. VanDeusen, Rachel J. Fenske, Haley N. Wienkes, Christopher G. England, Hector F. Valdovinos, Justin J. Jeffery, Todd E. Barnhart, Gregory W. Severin, Robert J. Nickles, Michelle E. Kimple, Matthew J. Merrins, Weibo Cai
Diabetes Aug 2017, 66 (8) 2163-2174; DOI: 10.2337/db16-1285
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