Diabetes: 67 (8)

August 01 2018; volume 67 issue 8

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Open Access
In This Issue of Diabetes
Diabetes 2018 Aug; 67 (8): 1455-1456. https://doi.org/10.2337/db18-ti08

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Commentary

Open Access
Strong Heart, Low Ceramides
William L. Holland and Scott A. Summers

Diabetes 2018 Aug; 67 (8): 1457-1460. https://doi.org/10.2337/dbi18-0018

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Diabetes Symposium: Emerging Areas of Islet Biology

This section features two articles from the 5th Diabetes Symposium held in conjunction with the ADA's 78th Scientific Sessions in Orlando, FL, 22–26 June 2018.
- Open Access
  Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization
  Ruth A. Singer and Lori Sussel
  
  Diabetes 2018 Aug; 67 (8): 1461-1470. https://doi.org/10.2337/dbi18-0001
  
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- Open Access
  Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors
  Angeliki M. Stamatouli, Zoe Quandt, Ana Luisa Perdigoto, Pamela L. Clark, Harriet Kluger, Sarah A. Weiss, Scott Gettinger, Mario Sznol, Arabella Young, Robert Rushakoff, James Lee, Jeffrey A. Bluestone, Mark Anderson and Kevan C. Herold
  
  Diabetes 2018 Aug; 67 (8): 1471-1480. https://doi.org/10.2337/dbi18-0002
  
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Methodology Review

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Altered Function of Antigen-Presenting Cells in Type 1 Diabetes: A Challenge for Antigen-Specific Immunotherapy?
Rémi J. Creusot, Jorge Postigo-Fernandez and Nato Teteloshvili

Diabetes 2018 Aug; 67 (8): 1481-1494. https://doi.org/10.2337/db17-1564

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Metabolism

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Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin
Isaac Asare-Bediako, Rebecca L. Paszkiewicz, Stella P. Kim, Orison O. Woolcott, Cathryn M. Kolka, Miguel A. Burch, Morvarid Kabir and Richard N. Bergman

Diabetes 2018 Aug; 67 (8): 1495-1503. https://doi.org/10.2337/db17-1520

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Enhanced Glucose Control Following Vertical Sleeve Gastrectomy Does Not Require a β-Cell Glucagon-Like Peptide 1 Receptor
Jonathan D. Douros, Alfor G. Lewis, Eric P. Smith, JingJing Niu, Megan Capozzi, April Wittmann, Jonathan Campbell, Jenny Tong, Constance Wagner, Parinaz Mahbod, Randy Seeley and David A. D’Alessio

Diabetes 2018 Aug; 67 (8): 1504-1511. https://doi.org/10.2337/db18-0081

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Obesity Studies

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The Transplantation of ω3 PUFA–Altered Gut Microbiota of fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders
Célia Bidu, Quentin Escoula, Sandrine Bellenger, Aymé Spor, Maxime Galan, Audrey Geissler, André Bouchot, Dominique Dardevet, Béatrice Morio, Patrice D. Cani, Laurent Lagrost, Michel Narce and Jérôme Bellenger

Diabetes 2018 Aug; 67 (8): 1512-1523. https://doi.org/10.2337/db17-1488

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Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A
Kazutaka Ueda, Eiki Takimoto, Qing Lu, Pangyen Liu, Nobuaki Fukuma, Yusuke Adachi, Ryo Suzuki, Shengpu Chou, Wendy Baur, Mark J. Aronovitz, Andrew S. Greenberg, Issei Komuro and Richard H. Karas

Diabetes 2018 Aug; 67 (8): 1524-1537. https://doi.org/10.2337/db17-1342

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Liraglutide Modulates Appetite and Body Weight Through Glucagon-Like Peptide 1 Receptor–Expressing Glutamatergic Neurons
Jessica M. Adams, Hongjuan Pei, Darleen A. Sandoval, Randy J. Seeley, Rui B. Chang, Stephen D. Liberles and David P. Olson

Diabetes 2018 Aug; 67 (8): 1538-1548. https://doi.org/10.2337/db17-1385

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Perivascular Adipose Tissue–Derived PDGF-D Contributes to Aortic Aneurysm Formation During Obesity
Ze-Bei Zhang, Cheng-Chao Ruan, Jing-Rong Lin, Lian Xu, Xiao-Hui Chen, Ya-Nan Du, Meng-Xia Fu, Ling-Ran Kong, Ding-Liang Zhu and Ping-Jin Gao

Diabetes 2018 Aug; 67 (8): 1549-1560. https://doi.org/10.2337/db18-0098

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Islet Studies

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Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation
Anil Kumar, Liora S. Katz, Anna M. Schulz, Misung Kim, Lee B. Honig, Lucy Li, Bennett Davenport, Dirk Homann, Adolfo Garcia-Ocaña, Mark A. Herman, Cole M. Haynes, Jerry E. Chipuk and Donald K. Scott

Diabetes 2018 Aug; 67 (8): 1561-1575. https://doi.org/10.2337/db17-0943

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Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response
Michelle R. Marasco, Abass M. Conteh, Christopher A. Reissaus, John E. Cupit, Evan M. Appleman, Raghavendra G. Mirmira and Amelia K. Linnemann

Diabetes 2018 Aug; 67 (8): 1576-1588. https://doi.org/10.2337/db17-1280

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Immunology and Transplantation

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TACI-Deficient Macrophages Protect Mice Against Metaflammation and Obesity-Induced Dysregulation of Glucose Homeostasis
Lunhua Liu, Karen Etsuko Inouye, Windy Rose Allman, Adam Steven Coleman, Shafiuddin Siddiqui, Gökhan Siddik Hotamisligil and Mustafa Akkoyunlu

Diabetes 2018 Aug; 67 (8): 1589-1603. https://doi.org/10.2337/db17-1089

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Pathophysiology

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Production of Elastin-Derived Peptides Contributes to the Development of Nonalcoholic Steatohepatitis
Béatrice Romier, Corinne Ivaldi, Hervé Sartelet, Andrea Heinz, Christian E.H. Schmelzer, Roselyne Garnotel, Alexandre Guillot, Jessica Jonquet, Eric Bertin, Jean-Louis Guéant, Jean-Marc Alberto, Jean-Pierre Bronowicki, Johanne Amoyel, Thinhinane Hocine, Laurent Duca, Pascal Maurice, Amar Bennasroune, Laurent Martiny, Laurent Debelle, Vincent Durlach and Sébastien Blaise

Diabetes 2018 Aug; 67 (8): 1604-1615. https://doi.org/10.2337/db17-0490

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Complications

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Vascular and Neural Complications in Type 2 Diabetic Rats: Improvement by Sacubitril/Valsartan Greater Than Valsartan Alone
Eric P. Davidson, Lawrence J. Coppey, Hanna Shevalye, Alexander Obrosov and Mark A. Yorek

Diabetes 2018 Aug; 67 (8): 1616-1626. https://doi.org/10.2337/db18-0062

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MicroRNA-129 and -335 Promote Diabetic Wound Healing by Inhibiting Sp1-Mediated MMP-9 Expression
Wei Wang, Chuan Yang, Xiao yi Wang, Li yan Zhou, Guo juan Lao, Dan Liu, Chuan Wang, Meng die Hu, Ting ting Zeng, Li Yan and Meng Ren

Diabetes 2018 Aug; 67 (8): 1627-1638. https://doi.org/10.2337/db17-1238

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Plasma Exosomes Contribute to Microvascular Damage in Diabetic Retinopathy by Activating the Classical Complement Pathway
Chao Huang, Kiera P. Fisher, Sandra S. Hammer, Svetlana Navitskaya, Gary J. Blanchard and Julia V. Busik

Diabetes 2018 Aug; 67 (8): 1639-1649. https://doi.org/10.2337/db17-1587

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Impaired Nociception in the Diabetic Ins2^+/Akita Mouse
Nisha Vastani, Franziska Guenther, Clive Gentry, Amazon L. Austin, Aileen J. King, Stuart Bevan and David A. Andersson

Diabetes 2018 Aug; 67 (8): 1650-1662. https://doi.org/10.2337/db17-1306

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Genetics/Genomes/Proteomics/Metabolomics

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Circulating Sphingolipids, Insulin, HOMA-IR, and HOMA-B: The Strong Heart Family Study
Rozenn N. Lemaitre, Chaoyu Yu, Andrew Hoofnagle, Nair Hari, Paul N. Jensen, Amanda M. Fretts, Jason G. Umans, Barbara V. Howard, Colleen M. Sitlani, David S. Siscovick, Irena B. King, Nona Sotoodehnia and Barbara McKnight

Diabetes 2018 Aug; 67 (8): 1663-1672. https://doi.org/10.2337/db17-1449

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Placental DNA Methylation Adaptation to Maternal Glycemic Response in Pregnancy
Andres Cardenas, Valerie Gagné-Ouellet, Catherine Allard, Diane Brisson, Patrice Perron, Luigi Bouchard and Marie-France Hivert

Diabetes 2018 Aug; 67 (8): 1673-1683. https://doi.org/10.2337/db18-0123

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Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study
Stephanie J. Loomis, Man Li, Nisa M. Maruthur, Abigail S. Baldridge, Kari E. North, Hao Mei, Alanna Morrison, April P. Carson, James S. Pankow, Eric Boerwinkle, Robert Scharpf, Laura J. Rasmussen-Torvik, Josef Coresh, Priya Duggal, Anna Köttgen and Elizabeth Selvin

Diabetes 2018 Aug; 67 (8): 1684-1696. https://doi.org/10.2337/db17-1362

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Issues and Events

Open Access
Issues and Events
Diabetes 2018 Aug; 67 (8): 1697. https://doi.org/10.2337/db18-ie08

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Table of Contents

In This Issue

Commentary

Diabetes Symposium: Emerging Areas of Islet Biology

This section features two articles from the 5th Diabetes Symposium held in conjunction with the ADA's 78th Scientific Sessions in Orlando, FL, 22–26 June 2018.

Methodology Review

Metabolism

Obesity Studies

Islet Studies

Immunology and Transplantation

Pathophysiology

Complications

Genetics/Genomes/Proteomics/Metabolomics

Issues and Events

In this Issue

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