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Table of Contents

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May 01 2019; volume 68 issue 5

In This Issue

  • Open Access
    In This Issue of Diabetes
    Diabetes 2019 May; 68 (5): 869-870. https://doi.org/10.2337/db19-ti05
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Perspectives in Diabetes

  • Open Access
    Functional Implications of DNA Methylation in Adipose Biology
    Xiang Ma and Sona Kang
    Diabetes 2019 May; 68 (5): 871-878. https://doi.org/10.2337/dbi18-0057
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  • Open Access
    The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes
    Anthony W. Purcell, Salvatore Sechi and Teresa P. DiLorenzo
    Diabetes 2019 May; 68 (5): 879-886. https://doi.org/10.2337/dbi18-0066
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  • Open Access
    Function and Mechanism of Long Noncoding RNAs in Adipocyte Biology
    Lei Sun and Jiandie D. Lin
    Diabetes 2019 May; 68 (5): 887-896. https://doi.org/10.2337/dbi18-0009
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Commentaries

  • Open Access
    GIP and GLP-1: Stepsiblings Rather Than Monozygotic Twins Within the Incretin Family
    Michael A. Nauck and Juris J. Meier
    Diabetes 2019 May; 68 (5): 897-900. https://doi.org/10.2337/dbi19-0005
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  • Open Access
    Stem Cell–Derived Islets: Next Steps for Histologic and Functional Assessment During Development as a Cellular Therapy for the Treatment of Diabetes
    Michael R. Rickels
    Diabetes 2019 May; 68 (5): 901-903. https://doi.org/10.2337/dbi18-0054
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  • Open Access
    Modern Methods of Transcriptomic and Peptidomic Profiling of Enteroendocrine Cells Promise Progress for a Better Understanding of (Patho)physiology and New Therapies for Obesity and Diabetes
    Burkhard Göke
    Diabetes 2019 May; 68 (5): 904-905. https://doi.org/10.2337/dbi18-0050
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Metabolism

  • You have accessRestricted Access
    Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals
    Lærke S. Gasbjerg, Mads M. Helsted, Bolette Hartmann, Mette H. Jensen, Maria B.N. Gabe, Alexander H. Sparre-Ulrich, Simon Veedfald, Signe Stensen, Amalie R. Lanng, Natasha C. Bergmann, Mikkel B. Christensen, Tina Vilsbøll, Jens J. Holst, Mette M. Rosenkilde and Filip K. Knop
    Diabetes 2019 May; 68 (5): 906-917. https://doi.org/10.2337/db18-1123
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    Fasting-Induced Transcription Factors Repress Vitamin D Bioactivation, a Mechanism for Vitamin D Deficiency in Diabetes
    Sanna-Mari Aatsinki, Mahmoud-Sobhy Elkhwanky, Outi Kummu, Mikko Karpale, Marcin Buler, Pirkko Viitala, Valtteri Rinne, Maija Mutikainen, Pasi Tavi, Andras Franko, Rudolf J. Wiesner, Kari T. Chambers, Brian N. Finck and Jukka Hakkola
    Diabetes 2019 May; 68 (5): 918-931. https://doi.org/10.2337/db18-1050
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    Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes
    Trevor P. Fidler, Alex Marti, Katelyn Gerth, Elizabeth A. Middleton, Robert A. Campbell, Matthew T. Rondina, Andrew S. Weyrich and E. Dale Abel
    Diabetes 2019 May; 68 (5): 932-938. https://doi.org/10.2337/db18-0981
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    Postprandial Aminogenic Insulin and Glucagon Secretion Can Stimulate Glucose Flux in Humans
    Teddy Ang, Clinton R. Bruce and Greg M. Kowalski
    Diabetes 2019 May; 68 (5): 939-946. https://doi.org/10.2337/db18-1138
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Obesity Studies

  • Open Access
    Melatonin Increases Brown Adipose Tissue Volume and Activity in Patients With Melatonin Deficiency: A Proof-of-Concept Study
    Bruno Halpern, Marcio C. Mancini, Clarissa Bueno, Isabella P. Barcelos, Maria Edna de Melo, Marcos S. Lima, Camila G. Carneiro, Marcelo T. Sapienza, Carlos Alberto Buchpiguel, Fernanda Gaspar do Amaral and José Cipolla-Neto
    Diabetes 2019 May; 68 (5): 947-952. https://doi.org/10.2337/db18-0956
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Islet Studies

  • You have accessRestricted Access
    Posttransplant Characterization of Long-term Functional hESC-Derived Pancreatic Endoderm Grafts
    Andrew R. Pepper, Antonio Bruni, Rena Pawlick, Doug O’Gorman, Tatsuya Kin, Aducio Thiesen and A.M. James Shapiro
    Diabetes 2019 May; 68 (5): 953-962. https://doi.org/10.2337/db18-0788
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  • Open Access
    Glucagon Receptor Antagonist–Stimulated α-Cell Proliferation Is Severely Restricted With Advanced Age
    Carol J. Lam, Matthew M. Rankin, Kourtney B. King, Melinda C. Wang, Brian C. Shook and Jake A. Kushner
    Diabetes 2019 May; 68 (5): 963-974. https://doi.org/10.2337/db18-1293
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    DNA Damage Does Not Cause BrdU Labeling of Mouse or Human β-Cells
    Rohit B. Sharma, Christine Darko, Xiaoying Zheng, Brian Gablaski and Laura C. Alonso
    Diabetes 2019 May; 68 (5): 975-987. https://doi.org/10.2337/db18-0761
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    HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes
    Mark A. Russell, Sambra D. Redick, David M. Blodgett, Sarah J. Richardson, Pia Leete, Lars Krogvold, Knut Dahl-Jørgensen, Rita Bottino, Marcela Brissova, Jason M. Spaeth, Jenny Aurielle B. Babon, Rachana Haliyur, Alvin C. Powers, Chaoxing Yang, Sally C. Kent, Alan G. Derr, Alper Kucukural, Manuel G. Garber, Noel G. Morgan and David M. Harlan
    Diabetes 2019 May; 68 (5): 988-1001. https://doi.org/10.2337/db18-0686
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Immunology and Transplantation

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    Altered Gut Microbiota Activate and Expand Insulin B15-23–Reactive CD8+ T Cells
    James A. Pearson, Dimitri Kakabadse, Joanne Davies, Jian Peng, Jeremy Warden-Smith, Simone Cuff, Mark Lewis, Larissa Camargo da Rosa, Li Wen and F. Susan Wong
    Diabetes 2019 May; 68 (5): 1002-1013. https://doi.org/10.2337/db18-0487
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Complications

  • Open Access
    Monosodium Urate Contributes to Retinal Inflammation and Progression of Diabetic Retinopathy
    Menaka C. Thounaojam, Annalisa Montemari, Folami L. Powell, Prerana Malla, Diana R. Gutsaeva, Alessandra Bachettoni, Guido Ripandelli, Andrea Repossi, Amany Tawfik, Pamela M. Martin, Francesco Facchiano and Manuela Bartoli
    Diabetes 2019 May; 68 (5): 1014-1025. https://doi.org/10.2337/db18-0912
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    Diabetes-Induced DUSP4 Reduction Promotes Podocyte Dysfunction and Progression of Diabetic Nephropathy
    Benoit Denhez, Marina Rousseau, David-Alexandre Dancosst, Farah Lizotte, Andréanne Guay, Mannix Auger-Messier, Anne Marie Côté and Pedro Geraldes
    Diabetes 2019 May; 68 (5): 1026-1039. https://doi.org/10.2337/db18-0837
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Pharmacology and Therapeutics

  • You have accessRestricted Access
    Fenofibrate Rescues Diabetes-Related Impairment of Ischemia-Mediated Angiogenesis by PPARα-Independent Modulation of Thioredoxin-Interacting Protein
    Jun Yuan, Joanne T.M. Tan, Kushwin Rajamani, Emma L. Solly, Emily J. King, Laura Lecce, Philippa J.L. Simpson, Yuen Ting Lam, Alicia J. Jenkins, Christina A. Bursill, Anthony C. Keech and Martin K.C. Ng
    Diabetes 2019 May; 68 (5): 1040-1053. https://doi.org/10.2337/db17-0926
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    The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1
    Jenny M. Brown, Jarrad M. Scarlett, Miles E. Matsen, Hong T. Nguyen, Anna Secher, Rasmus Jorgensen, Gregory J. Morton and Michael W. Schwartz
    Diabetes 2019 May; 68 (5): 1054-1061. https://doi.org/10.2337/db19-0025
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Genetics/Genomes/Proteomics/Metabolomics

  • Open Access
    Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling
    Geoffrey P. Roberts, Pierre Larraufie, Paul Richards, Richard G. Kay, Sam G. Galvin, Emily L. Miedzybrodzka, Andrew Leiter, H. Joyce Li, Leslie L. Glass, Marcella K.L. Ma, Brian Lam, Giles S.H. Yeo, Raphaël Scharfmann, Davide Chiarugi, Richard H. Hardwick, Frank Reimann and Fiona M. Gribble
    Diabetes 2019 May; 68 (5): 1062-1072. https://doi.org/10.2337/db18-0883
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    A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease
    Jiantao Ma, Jana Nano, Jingzhong Ding, Yinan Zheng, Rachel Hennein, Chunyu Liu, Elizabeth K. Speliotes, Tianxiao Huan, Ci Song, Michael M. Mendelson, Roby Joehanes, Michelle T. Long, Liming Liang, Jennifer A. Smith, Lindsay M. Reynolds, Mohsen Ghanbari, Taulant Muka, Joyce B.J. van Meurs, Louise J.M. Alferink, Oscar H. Franco, Abbas Dehghan, Scott Ratliff, Wei Zhao, Lawrence Bielak, Sharon L.R. Kardia, Patricia A. Peyser, Hongyan Ning, Lisa B. VanWagner, Donald M. Lloyd-Jones, John Jeffrey Carr, Philip Greenland, Alice H. Lichtenstein, Frank B. Hu, Yongmei Liu, Lifang Hou, Sarwa Darwish Murad and Daniel Levy
    Diabetes 2019 May; 68 (5): 1073-1083. https://doi.org/10.2337/db18-1193
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    Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes
    Prapaporn Jungtrakoon, Jun Shirakawa, Patinut Buranasupkajorn, Manoj K. Gupta, Dario F. De Jesus, Marcus G. Pezzolesi, Aussara Panya, Timothy Hastings, Chutima Chanprasert, Christine Mendonca, Rohit N. Kulkarni and Alessandro Doria
    Diabetes 2019 May; 68 (5): 1084-1093. https://doi.org/10.2337/db17-0821
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Erratum

  • Open Access
    Erratum. Sodium–Glucose Cotransporter 2 Inhibition and Diabetic Kidney Disease. Diabetes 2019;68:248–257
    Radica Z. Alicic, Joshua J. Neumiller, Emily J. Johnson, Brad Dieter and Katherine R. Tuttle
    Diabetes 2019 May; 68 (5): 1094. https://doi.org/10.2337/db19-er05a
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Issues and Events

  • Open Access
    Issues and Events
    Diabetes 2019 May; 68 (5): 1095. https://doi.org/10.2337/db19-ie05
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Diabetes: 68 (5)

In this Issue

May 2019, 68(5)
  • Table of Contents
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  • In This Issue
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  • Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis
  • Latent Autoimmune Diabetes in Adults
  • Poverty and Obesity in the U.S.
  • The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion
  • A Polymorphism in the Glucocorticoid Receptor Gene, Which Decreases Sensitivity to Glucocorticoids In Vivo, Is Associated With Low Insulin and Cholesterol Levels
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