On the cover: Three-dimensional confocal microscopic image of pancreatic tissue from a human donor. Islets are stained with a pan-endocrine antibody marker (HPi1, yellow), and blood vessels are stained with an endothelial cell marker (CD31, red). Image courtesy of Michael P. Dybala and Manami Hara, Department of Medicine, The University of Chicago, Chicago, IL. Their article, “Heterogeneity of the Human Pancreatic Islet,” appears in this issue of Diabetes (p. 1230).


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