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Genetics/Genomes/Proteomics/Metabolomics

Association of the 1q25 Diabetes-Specific Coronary Heart Disease Locus With Alterations of the γ-Glutamyl Cycle and Increased Methylglyoxal Levels in Endothelial Cells

  1. Caterina Pipino1,2,3,
  2. Hetal Shah1,2,
  3. Sabrina Prudente4,
  4. Natalia Di Pietro3,
  5. Lixia Zeng5,
  6. Kyoungmin Park1,2,
  7. Vincenzo Trischitta6,7,
  8. Subramanian Pennathur5,
  9. Assunta Pandolfi3 and
  10. Alessandro Doria1,2⇑
  1. 1Research Division, Joslin Diabetes Center, Boston, MA
  2. 2Department of Medicine, Harvard Medical School, Boston, MA
  3. 3Department of Medical, Oral and Biotechnological Sciences, Center for Advanced Studies and Technology - CAST (ex CeSI-MeT), University G. d’Annunzio of Chieti-Pescara, Chieti, Italy
  4. 4Research Unit of Metabolic and Cardiovascular Diseases, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
  5. 5Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI
  6. 6Research Unit of Diabetes and Endocrine Diseases, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
  7. 7Department of Experimental Medicine, Sapienza University, Rome, Italy
  1. Corresponding author: Alessandro Doria, alessandro.doria{at}joslin.harvard.edu
Diabetes 2020 Oct; 69(10): 2206-2216. https://doi.org/10.2337/db20-0475
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Article Information

vol. 69 no. 10 2206-2216
DOI 
https://doi.org/10.2337/db20-0475
PubMed 
32651240

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • Received May 5, 2020
  • Accepted July 3, 2020
  • Published in print September 21, 2020.
  • Published online ahead of print July 10, 2020.

Article Versions

  • Previous version (July 10, 2020 - 09:55).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by the American Diabetes Association https://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at https://www.diabetesjournals.org/content/license.

Author Information

  1. Caterina Pipino1,2,3,
  2. Hetal Shah1,2,
  3. Sabrina Prudente4,
  4. Natalia Di Pietro3,
  5. Lixia Zeng5,
  6. Kyoungmin Park1,2,
  7. Vincenzo Trischitta6,7,
  8. Subramanian Pennathur5,
  9. Assunta Pandolfi3 and
  10. Alessandro Doria1,2⇑
  1. 1Research Division, Joslin Diabetes Center, Boston, MA
  2. 2Department of Medicine, Harvard Medical School, Boston, MA
  3. 3Department of Medical, Oral and Biotechnological Sciences, Center for Advanced Studies and Technology - CAST (ex CeSI-MeT), University G. d’Annunzio of Chieti-Pescara, Chieti, Italy
  4. 4Research Unit of Metabolic and Cardiovascular Diseases, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
  5. 5Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI
  6. 6Research Unit of Diabetes and Endocrine Diseases, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
  7. 7Department of Experimental Medicine, Sapienza University, Rome, Italy
  1. Corresponding author: Alessandro Doria, alessandro.doria{at}joslin.harvard.edu
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Association of the 1q25 Diabetes-Specific Coronary Heart Disease Locus With Alterations of the γ-Glutamyl Cycle and Increased Methylglyoxal Levels in Endothelial Cells
Caterina Pipino, Hetal Shah, Sabrina Prudente, Natalia Di Pietro, Lixia Zeng, Kyoungmin Park, Vincenzo Trischitta, Subramanian Pennathur, Assunta Pandolfi, Alessandro Doria
Diabetes Oct 2020, 69 (10) 2206-2216; DOI: 10.2337/db20-0475

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Association of the 1q25 Diabetes-Specific Coronary Heart Disease Locus With Alterations of the γ-Glutamyl Cycle and Increased Methylglyoxal Levels in Endothelial Cells
Caterina Pipino, Hetal Shah, Sabrina Prudente, Natalia Di Pietro, Lixia Zeng, Kyoungmin Park, Vincenzo Trischitta, Subramanian Pennathur, Assunta Pandolfi, Alessandro Doria
Diabetes Oct 2020, 69 (10) 2206-2216; DOI: 10.2337/db20-0475
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