L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
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vol. 69 no. 4 614-623
PubMed
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History
- Received August 5, 2019
- Accepted January 22, 2020
- Published in print March 20, 2020.
- Published online ahead of print February 10, 2020.
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- Previous version (February 10, 2020 - 14:18).
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© 2020 by the American Diabetes Association. https://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at https://www.diabetesjournals.org/content/license.
Author Information
- Mari Lilith Lund1,
- Giovanni Sorrentino2,
- Kristoffer Lihme Egerod1,
- Chantal Kroone3,
- Brynjulf Mortensen4,
- Filip Krag Knop1,4,5,6,
- Frank Reimann7,
- Fiona M. Gribble7,
- Daniel J. Drucker8,
- Eelco J.P. de Koning9,10,
- Kristina Schoonjans2,
- Fredrik Bäckhed1,11,
- Thue W. Schwartz1,12 and
- Natalia Petersen1⇑
- 1Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- 2Laboratory of Metabolic Signaling, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
- 3Department of Thrombosis and Hemostasis, Leiden University Medical Centre, Leiden, the Netherlands
- 4Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
- 5Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- 6Steno Diabetes Center Copenhagen, Gentofte, Denmark
- 7Institute of Metabolic Science and Medical Research Council Metabolic Diseases Unit, University of Cambridge, Addenbrooke’s Hospital, Cambridge, U.K.
- 8Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
- 9Department of Medicine, Leiden University Medical Centre, Leiden, the Netherlands
- 10Hubrecht Institute/Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) and University Medical Center Utrecht, Utrecht, the Netherlands
- 11Department of Molecular and Clinical Medicine at Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
- 12Laboratory for Molecular Pharmacology, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- Corresponding author: Natalia Petersen, napt{at}novonordisk.com
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April 2020, 69(4)
L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
