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Obesity Studies

Genetic Causes of Severe Childhood Obesity: A Remarkably High Prevalence in an Inbred Population of Pakistan

  1. Sadia Saeed1,2,
  2. Muhammad Arslan3,
  3. Jaida Manzoor4,
  4. Sadia M. Din5,
  5. Qasim M. Janjua5,6,
  6. Hina Ayesha7,
  7. Qura-tul Ain5,
  8. Laraib Inam3,
  9. Stephane Lobbens1,
  10. Emmanuel Vaillant1,
  11. Emmanuelle Durand1,
  12. Mehdi Derhourhi1,
  13. Souhila Amanzougarene1,
  14. Alaa Badreddine1,
  15. Lionel Berberian1,
  16. Stefan Gaget1,
  17. Waqas I. Khan8,
  18. Taeed A. Butt9,
  19. Amélie Bonnefond1,2⇑ and
  20. Philippe Froguel1,2⇑
  1. 1Université de Lille, INSERM UMR1283, CNRS-UMR 8199–European Genomic Institute for Diabetes, and Lille University Hospital, Lille, France
  2. 2Department of Metabolism, Digestion and Reproduction, Imperial College London, London, U.K.
  3. 3School of Life Sciences, Forman Christian College (A Chartered University), Lahore, Pakistan
  4. 4Department of Paediatric Endocrinology, Children’s Hospital, Lahore, Pakistan
  5. 5Institute of Molecular Biology and Biotechnology, University of Lahore, Lahore, Pakistan
  6. 6Department of Physiology, University College of Medicine and Dentistry, University of Lahore, Lahore, Pakistan
  7. 7Department of Paediatrics, Punjab Medical College, Faisalabad, Pakistan
  8. 8The Children Hospital and the Institute of Child Health, Multan, Pakistan
  9. 9Department of Pediatrics, Fatima Memorial Hospital, Lahore, Pakistan
  1. Corresponding author: Philippe Froguel, p.froguel{at}imperial.ac.uk, or Amélie Bonnefond, amelie.bonnefond{at}cnrs.fr
Diabetes 2020 Jul; 69(7): 1424-1438. https://doi.org/10.2337/db19-1238
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Article Information

vol. 69 no. 7 1424-1438
DOI 
https://doi.org/10.2337/db19-1238
PubMed 
32349990

Published By 
American Diabetes Association
Print ISSN 
0012-1797
Online ISSN 
1939-327X
History 
  • Received December 16, 2019
  • Accepted April 25, 2020
  • Published in print June 19, 2020.
  • Published online ahead of print April 29, 2020.

Article Versions

  • Previous version (April 29, 2020 - 13:57).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by the American Diabetes Association https://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at https://www.diabetesjournals.org/content/license.

Author Information

  1. Sadia Saeed1,2,
  2. Muhammad Arslan3,
  3. Jaida Manzoor4,
  4. Sadia M. Din5,
  5. Qasim M. Janjua5,6,
  6. Hina Ayesha7,
  7. Qura-tul Ain5,
  8. Laraib Inam3,
  9. Stephane Lobbens1,
  10. Emmanuel Vaillant1,
  11. Emmanuelle Durand1,
  12. Mehdi Derhourhi1,
  13. Souhila Amanzougarene1,
  14. Alaa Badreddine1,
  15. Lionel Berberian1,
  16. Stefan Gaget1,
  17. Waqas I. Khan8,
  18. Taeed A. Butt9,
  19. Amélie Bonnefond1,2⇑ and
  20. Philippe Froguel1,2⇑
  1. 1Université de Lille, INSERM UMR1283, CNRS-UMR 8199–European Genomic Institute for Diabetes, and Lille University Hospital, Lille, France
  2. 2Department of Metabolism, Digestion and Reproduction, Imperial College London, London, U.K.
  3. 3School of Life Sciences, Forman Christian College (A Chartered University), Lahore, Pakistan
  4. 4Department of Paediatric Endocrinology, Children’s Hospital, Lahore, Pakistan
  5. 5Institute of Molecular Biology and Biotechnology, University of Lahore, Lahore, Pakistan
  6. 6Department of Physiology, University College of Medicine and Dentistry, University of Lahore, Lahore, Pakistan
  7. 7Department of Paediatrics, Punjab Medical College, Faisalabad, Pakistan
  8. 8The Children Hospital and the Institute of Child Health, Multan, Pakistan
  9. 9Department of Pediatrics, Fatima Memorial Hospital, Lahore, Pakistan
  1. Corresponding author: Philippe Froguel, p.froguel{at}imperial.ac.uk, or Amélie Bonnefond, amelie.bonnefond{at}cnrs.fr
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Genetic Causes of Severe Childhood Obesity: A Remarkably High Prevalence in an Inbred Population of Pakistan
Sadia Saeed, Muhammad Arslan, Jaida Manzoor, Sadia M. Din, Qasim M. Janjua, Hina Ayesha, Qura-tul Ain, Laraib Inam, Stephane Lobbens, Emmanuel Vaillant, Emmanuelle Durand, Mehdi Derhourhi, Souhila Amanzougarene, Alaa Badreddine, Lionel Berberian, Stefan Gaget, Waqas I. Khan, Taeed A. Butt, Amélie Bonnefond, Philippe Froguel
Diabetes Jul 2020, 69 (7) 1424-1438; DOI: 10.2337/db19-1238

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Genetic Causes of Severe Childhood Obesity: A Remarkably High Prevalence in an Inbred Population of Pakistan
Sadia Saeed, Muhammad Arslan, Jaida Manzoor, Sadia M. Din, Qasim M. Janjua, Hina Ayesha, Qura-tul Ain, Laraib Inam, Stephane Lobbens, Emmanuel Vaillant, Emmanuelle Durand, Mehdi Derhourhi, Souhila Amanzougarene, Alaa Badreddine, Lionel Berberian, Stefan Gaget, Waqas I. Khan, Taeed A. Butt, Amélie Bonnefond, Philippe Froguel
Diabetes Jul 2020, 69 (7) 1424-1438; DOI: 10.2337/db19-1238
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