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Genetics/Genomes/Proteomics/Metabolomics

Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children

  1. Lue Ping Zhao1⇑,
  2. George K. Papadopoulos2,§⇑,
  3. William W. Kwok3,
  4. Antonis K. Moustakas4,
  5. George P. Bondinas2,
  6. Helena Elding Larsson5,
  7. Johnny Ludvigsson6,
  8. Claude Marcus7,
  9. Ulf Samuelsson6,
  10. Ruihan Wang8,
  11. Chul-Woo Pyo8,
  12. Wyatt C. Nelson8,
  13. Daniel E. Geraghty8 and
  14. Åke Lernmark5⇑
  1. 1Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA
  2. 2Laboratory of Biophysics, Biochemistry, Biomaterials and Bioprocessing, Faculty of Agricultural Technology, Technological Educational Institute of Epirus, Arta, Greece
  3. 3Benaroya Research Institute at Virginia Mason, Seattle, WA
  4. 4Department of Food Science and Technology, Faculty of Environmental Sciences, Ionian University, Argostoli, Cephalonia, Greece
  5. 5Department of Clinical Sciences, Lund University CRC, Skåne University Hospital, Malmö, Sweden
  6. 6Crown Princess Victoria Children’s Hospital, Region Östergötland, and Division of Pediatrics, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden
  7. 7Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
  8. 8Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
  1. Corresponding authors: Lue Ping Zhao, lzhao{at}fredhutch.org, George K. Papadopoulos, papadopg{at}gmail.com, and Åke Lernmark, ake.lernmark{at}med.lu.se
Diabetes 2020 Jul; 69(7): 1573-1587. https://doi.org/10.2337/db20-0075
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Data supplements

  • Supplemental material, Zhao, et al.

    Supplemental material is available at https://doi.org/10.2337/db20-4567/suppl.12053640.

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    Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children
    Lue Ping Zhao, George K. Papadopoulos, William W. Kwok, Antonis K. Moustakas, George P. Bondinas, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark
    Diabetes Jul 2020, 69 (7) 1573-1587; DOI: 10.2337/db20-0075

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    Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children
    Lue Ping Zhao, George K. Papadopoulos, William W. Kwok, Antonis K. Moustakas, George P. Bondinas, Helena Elding Larsson, Johnny Ludvigsson, Claude Marcus, Ulf Samuelsson, Ruihan Wang, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark
    Diabetes Jul 2020, 69 (7) 1573-1587; DOI: 10.2337/db20-0075
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