Skip to main content
  • More from ADA
    • Diabetes Care
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care in Diabetes
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care
  • Subscribe
  • Log in
  • My Cart
  • Follow ada on Twitter
  • RSS
  • Visit ada on Facebook
Diabetes

Advanced Search

Main menu

  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • ADA Scientific Sessions Abstracts
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • ADA Scientific Sessions Abstracts
    • Diabetes COVID-19 Article Collection
    • Diabetes Symposium 2020
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Submit Cover Art
    • ADA Journal Policies
    • Instructions for Authors
    • ADA Peer Review
  • More from ADA
    • Diabetes Care
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care in Diabetes
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care

User menu

  • Subscribe
  • Log in
  • My Cart

Search

  • Advanced search
Diabetes
  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • ADA Scientific Sessions Abstracts
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • ADA Scientific Sessions Abstracts
    • Diabetes COVID-19 Article Collection
    • Diabetes Symposium 2020
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Submit Cover Art
    • ADA Journal Policies
    • Instructions for Authors
    • ADA Peer Review
Poster Presentations: Acute and Chronic Complications

572-P: Association of Sight-Threatening Diabetic Retinopathy in Type 1 Diabetes with Subclinical Atherosclerosis Disease Burden: Five-Year Indian Study

  1. KIRAN SHAH,
  2. NATARAJAN SUNDARAM,
  3. LOTIKA S. PUROHIT,
  4. PETER P. TOTH,
  5. AKSHAY R. KOTHARI and
  6. SUNIL GUPTA
  1. Mumbai, India, Sterling, IL, Nagpur, India
Diabetes 2020 Jun; 69(Supplement 1): -. https://doi.org/10.2337/db20-572-P
Previous
  • Article
  • Figures & Tables
  • Info & Metrics
Loading

Abstract

We conducted a cross sectional study in 314 T1DM patients (50% with Sight Threatening Diabetic Retinopathy (STDR). B-mode carotid ultrasound, CT coronary angiogram was done after excluding history of CV disease and CKD. Table summarizes demographic, biochemical and imaging parameters. The plaque burden, Carotid Intima Media Thickness (CIMT) and Coronary Calcium (CAC) scores were significantly higher (p<0.0001) in STDR group than No Diabetic Retinopathy (NDR) group. Prevalence of plaque burden was higher in STDR (68.7%) vs. NDR (4.45%). There was no significant correlation between age and CIMT (r= 0.0147). In STDR group, BMI and CIMT showed linear correlation (r=0.0318), there was a strong correlation between carotid plaques and triglycerides (TGs). High CAC scores correlated with higher cholesterol levels. CAC and CIMT had linear correlation with TGs but no correlation with LDL-C. Patients with high CAC scores had high CIMT and vice versa. Multivariate logistic regression analysis showed stronger correlation of carotid plaques with CIMT (p=0.0004) and TGs (p= 0.0295, r= 0.0157) than CAC (p= 0.0605 NS). STDR is an independent predictor of carotid plaques and is a marker of high atherosclerotic burden in T1DM. This association describes that T1DM patients with STDR are at higher CV risk and need aggressive, comprehensive follow up to prevent CV disease.

Figure1
  • Download figure
  • Open in new tab
  • Download powerpoint

Disclosure K. Shah: None. N. Sundaram: None. L.S. Purohit: None. P.P. Toth: Consultant; Self; Amarin Corporation, Amgen, Kowa Research Institute, Inc., Theravance Biopharma. Speaker’s Bureau; Self; Amarin Corporation, Amgen, Novo Nordisk Inc., Regeneron Pharmaceuticals, Sanofi. A.R. Kothari: None. S. Gupta: None.

  • © 2020 by the American Diabetes Association
http://www.diabetesjournals.org/content/license

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

Previous
Back to top
Diabetes: 69 (Supplement 1)

In this Issue

June 2020, 69(Supplement 1)
  • Table of Contents
  • Index by Author
Sign up to receive current issue alerts
View Selected Citations (0)
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word about Diabetes.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
572-P: Association of Sight-Threatening Diabetic Retinopathy in Type 1 Diabetes with Subclinical Atherosclerosis Disease Burden: Five-Year Indian Study
(Your Name) has forwarded a page to you from Diabetes
(Your Name) thought you would like to see this page from the Diabetes web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
572-P: Association of Sight-Threatening Diabetic Retinopathy in Type 1 Diabetes with Subclinical Atherosclerosis Disease Burden: Five-Year Indian Study
KIRAN SHAH, NATARAJAN SUNDARAM, LOTIKA S. PUROHIT, PETER P. TOTH, AKSHAY R. KOTHARI, SUNIL GUPTA
Diabetes Jun 2020, 69 (Supplement 1) 572-P; DOI: 10.2337/db20-572-P

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Add to Selected Citations
Share

572-P: Association of Sight-Threatening Diabetic Retinopathy in Type 1 Diabetes with Subclinical Atherosclerosis Disease Burden: Five-Year Indian Study
KIRAN SHAH, NATARAJAN SUNDARAM, LOTIKA S. PUROHIT, PETER P. TOTH, AKSHAY R. KOTHARI, SUNIL GUPTA
Diabetes Jun 2020, 69 (Supplement 1) 572-P; DOI: 10.2337/db20-572-P
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Figures & Tables
  • Info & Metrics

Related Articles

Cited By...

More in this TOC Section

Poster Presentations: Acute and Chronic Complications

  • 414-P: Hand-Grip Strength and Type 2 Diabetes Are Mutually Independent Predictors of Cardiovascular Events and of Mortality in Patients with Established Cardiovascular Disease
  • 587-P: The Relationship between Metabolic Index, Liver Enzyme Index, and the Incidence of Diabetes: The Jinchang Cohort Study
  • 472-P: The Profiles of MicroRNAs from Urinary Extracellular Vesicles (EVS) Prepared by Various Isolation Methods and Their Correlation with Serum EV MicroRNAs in Patients with Type 2 Diabetes and Diabetic Nephropathy
Show more Poster Presentations: Acute and Chronic Complications

P: Complications—Retinopathy

  • 564-P: Differences in Diabetic Retinopathy Prevalence and Progression between Aboriginal and Anglo-Celt Australians: The Fremantle Diabetes Study Phase II
  • 569-P: Plasma Metabolomic Profiling of Diabetic Macular Edema
  • 573-P: Construction and Validation of a Hierarchical-Driven Network for Decoding the Potential Molecular Mechanisms in Diabetic Microvascular Complications
Show more P: Complications—Retinopathy

Similar Articles

Navigate

  • Current Issue
  • Online Ahead of Print
  • Scientific Sessions Abstracts
  • Collections
  • Archives
  • Submit
  • Subscribe
  • Email Alerts
  • RSS Feeds

More Information

  • About the Journal
  • Instructions for Authors
  • Journal Policies
  • Reprints and Permissions
  • Advertising
  • Privacy Policy: ADA Journals
  • Copyright Notice/Public Access Policy
  • Contact Us

Other ADA Resources

  • Diabetes Care
  • Clinical Diabetes
  • Diabetes Spectrum
  • Scientific Sessions Abstracts
  • Standards of Medical Care in Diabetes
  • BMJ Open - Diabetes Research & Care
  • Professional Books
  • Diabetes Forecast

 

  • DiabetesJournals.org
  • Diabetes Core Update
  • ADA's DiabetesPro
  • ADA Member Directory
  • Diabetes.org

© 2021 by the American Diabetes Association. Diabetes Print ISSN: 0012-1797, Online ISSN: 1939-327X.