Diabetes: 70 (1)

January 01 2021; volume 70 issue 1

Perspectives in Diabetes

Open Access
SGLT2 Inhibition for CKD and Cardiovascular Disease in Type 2 Diabetes: Report of a Scientific Workshop Sponsored by the National Kidney Foundation
Katherine R. Tuttle, Frank C. Brosius, Matthew A. Cavender, Paola Fioretto, Kevin J. Fowler, Hiddo J.L. Heerspink, Tom Manley, Darren K. McGuire, Mark E. Molitch, Amy K. Mottl, Leigh Perreault, Sylvia E. Rosas, Peter Rossing, Laura Sola, Volker Vallon, Christoph Wanner and Vlado Perkovic

Diabetes 2021 Jan; 70 (1): 1-16. https://doi.org/10.2337/dbi20-0040

Add to Selected Citations
You have accessRestricted Access
Deciphering the Complex Communication Networks That Orchestrate Pancreatic Islet Function
Jonathan Weitz, Danusa Menegaz and Alejandro Caicedo

Diabetes 2021 Jan; 70 (1): 17-26. https://doi.org/10.2337/dbi19-0033

Add to Selected Citations

Commentary

Open Access
Lifting the Veil on the “Phosphate Flush,” a Cryptic Phenomenon of Experimental Pancreatic Islet Physiology
Franz Matschinsky and David Wilson

Diabetes 2021 Jan; 70 (1): 27-28. https://doi.org/10.2337/dbi20-0038

Add to Selected Citations

ADA Award Lectures

Open Access
“Treasure Your Exceptions”—Studying Human Extreme Phenotypes to Illuminate Metabolic Health and Disease: The 2019 Banting Medal for Scientific Achievement Lecture
Stephen O’Rahilly

Diabetes 2021 Jan; 70 (1): 29-38. https://doi.org/10.2337/dbi19-0037

Add to Selected Citations
Open Access
Linking Kidney and Cardiovascular Complications in Diabetes—Impact on Prognostication and Treatment: The 2019 Edwin Bierman Award Lecture
Peter Rossing, Frederik Persson, Marie Frimodt-Møller and Tine Willum Hansen

Diabetes 2021 Jan; 70 (1): 39-50. https://doi.org/10.2337/dbi19-0038

Add to Selected Citations

Metabolism

You have accessRestricted Access
Cardiac Autophagy Deficiency Attenuates ANP Production and Disrupts Myocardial-Adipose Cross Talk, Leading to Increased Fat Accumulation and Metabolic Dysfunction
Erfei Song, Daniel Da Eira, Shailee Jani, Diane Sepa-Kishi, Vivian Vu, Howard Hunter, Mi Lai, Michael B. Wheeler, Rolando B. Ceddia and Gary Sweeney

Diabetes 2021 Jan; 70 (1): 51-61. https://doi.org/10.2337/db19-0762

Add to Selected Citations
You have accessRestricted Access
Central Regulation of Branched-Chain Amino Acids Is Mediated by AgRP Neurons
Ritchel B. Gannaban, Cherl NamKoong, Henry H. Ruiz, Hyung Jin Choi and Andrew C. Shin

Diabetes 2021 Jan; 70 (1): 62-75. https://doi.org/10.2337/db20-0510

Add to Selected Citations
You have accessRestricted Access
Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy
Camille Gamblin, Christine Rouault, Amélie Lacombe, Francina Langa-Vives, Dominique Farabos, Antonin Lamaziere, Karine Clément, Emmanuel L. Gautier, Laurent Yvan-Charvet and Isabelle Dugail

Diabetes 2021 Jan; 70 (1): 76-90. https://doi.org/10.2337/db20-0578

Add to Selected Citations
You have accessRestricted Access
Small Amounts of Dietary Medium-Chain Fatty Acids Protect Against Insulin Resistance During Caloric Excess in Humans
Anne-Marie Lundsgaard, Andreas M. Fritzen, Kim A. Sjøberg, Maximilian Kleinert, Erik A. Richter and Bente Kiens

Diabetes 2021 Jan; 70 (1): 91-98. https://doi.org/10.2337/db20-0582

Add to Selected Citations

Obesity Studies

You have accessRestricted Access
Glucose Sensing Mediated by Portal Glucagon-Like Peptide 1 Receptor Is Markedly Impaired in Insulin-Resistant Obese Animals
Charles-Henri Malbert, Alain Chauvin, Michael Horowitz and Karen L. Jones

Diabetes 2021 Jan; 70 (1): 99-110. https://doi.org/10.2337/db20-0361

Add to Selected Citations

Islet Studies

Open Access
XPR1 Mediates the Pancreatic β-Cell Phosphate Flush
Christopher J. Barker, Fernando Henrique Galvão Tessaro, Sabrina de Souza Ferreira, Rafael Simas, Thais S. Ayala, Martin Köhler, Subu Surendran Rajasekaran, Joilson O. Martins, Elisabetta Darè and Per-Olof Berggren

Diabetes 2021 Jan; 70 (1): 111-118. https://doi.org/10.2337/db19-0633

Add to Selected Citations
You have accessRestricted Access
Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Mice With Diet-Induced Obesity
Xing Ming, Arthur C.K. Chung, Dandan Mao, Huanyi Cao, Baoqi Fan, Willy K.K. Wong, Chin Chung Ho, Heung Man Lee, Kristina Schoonjans, Johan Auwerx, Guy A. Rutter, Juliana C.N. Chan, Xiao Yu Tian and Alice P.S. Kong

Diabetes 2021 Jan; 70 (1): 119-131. https://doi.org/10.2337/db20-0339

Add to Selected Citations
You have accessRestricted Access
Adiponectin Promotes Maternal β-Cell Expansion Through Placental Lactogen Expression
Liping Qiao, Sarah Saget, Cindy Lu, William W. Hay, Gerard Karsenty and Jianhua Shao

Diabetes 2021 Jan; 70 (1): 132-142. https://doi.org/10.2337/db20-0471

Add to Selected Citations
You have accessRestricted Access
Induction of Core Circadian Clock Transcription Factor Bmal1 Enhances β-Cell Function and Protects Against Obesity-Induced Glucose Intolerance
Kuntol Rakshit and Aleksey V. Matveyenko

Diabetes 2021 Jan; 70 (1): 143-154. https://doi.org/10.2337/db20-0192

Add to Selected Citations
You have accessRestricted Access
Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function
Seokwon Jo, Amber Lockridge, Ramkumar Mohan, Nicholas Esch, Regina Schlichting, Neha Panigrahy, Ahmad Essawy, Eric Gustafson and Emilyn U. Alejandro

Diabetes 2021 Jan; 70 (1): 155-170. https://doi.org/10.2337/db20-0057

Add to Selected Citations

Immunology and Transplantation

Open Access
InsB9-23 Gene Transfer to Hepatocyte-Based Combined Therapy Abrogates Recurrence of Type 1 Diabetes After Islet Transplantation
Fabio Russo, Antonio Citro, Giorgia Squeri, Francesca Sanvito, Paolo Monti, Silvia Gregori, Maria Grazia Roncarolo and Andrea Annoni

Diabetes 2021 Jan; 70 (1): 171-181. https://doi.org/10.2337/db19-1249

Add to Selected Citations

Pathophysiology

Open Access
Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation
Young Jin, Yul Ji, Yaechan Song, Sung Sik Choe, Yong Geun Jeon, Heeju Na, Tae Wook Nam, Hye Jeong Kim, Hahn Nahmgoong, Sung Min Kim, Jae-woo Kim, Ki Taek Nam, Je Kyung Seong, Daehee Hwang, Chan Bae Park, In Hye Lee, Jae Bum Kim and Han-Woong Lee

Diabetes 2021 Jan; 70 (1): 182-195. https://doi.org/10.2337/db19-1239

Add to Selected Citations
You have accessRestricted Access
The Mineralocorticoid Receptor Antagonist Eplerenone Suppresses Interstitial Fibrosis in Subcutaneous Adipose Tissue in Patients With Type 2 Diabetes
Marie Louise Johansen, Jaime Ibarrola, Amaya Fernández-Celis, Morten Schou, Mette Pauli Sonne, Maria Refsgaard Holm, Jon Rasmussen, Flemming Dela, Frederic Jaisser, Jens Faber, Patrick Rossignol, Natalia Lopez-Andres and Caroline Kistorp

Diabetes 2021 Jan; 70 (1): 196-203. https://doi.org/10.2337/db20-0394

Add to Selected Citations
You have accessRestricted Access
Effect of Mild Physiologic Hyperglycemia on Insulin Secretion, Insulin Clearance, and Insulin Sensitivity in Healthy Glucose-Tolerant Subjects
Aurora Merovci, Devjit Tripathy, Xi Chen, Ivan Valdez, Muhammad Abdul-Ghani, Carolina Solis-Herrera, Amalia Gastaldelli and Ralph A. DeFronzo

Diabetes 2021 Jan; 70 (1): 204-213. https://doi.org/10.2337/db20-0039

Add to Selected Citations
You have accessRestricted Access
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway
Zhuo Mao, Mingji Feng, Zhuoran Li, Minsi Zhou, Langning Xu, Ke Pan, Shaoxiang Wang, Wen Su and Weizhen Zhang

Diabetes 2021 Jan; 70 (1): 214-226. https://doi.org/10.2337/db20-0619

Add to Selected Citations

Complications

You have accessRestricted Access
Long Noncoding RNA MALAT1 and Regulation of the Antioxidant Defense System in Diabetic Retinopathy
Rakesh Radhakrishnan and Renu A. Kowluru

Diabetes 2021 Jan; 70 (1): 227-239. https://doi.org/10.2337/db20-0375

Add to Selected Citations
You have accessRestricted Access
CD31⁺ Extracellular Vesicles From Patients With Type 2 Diabetes Shuttle a miRNA Signature Associated With Cardiovascular Complications
Francesco Prattichizzo, Valeria De Nigris, Jacopo Sabbatinelli, Angelica Giuliani, Carlos Castaño, Marcelina Párrizas, Isabel Crespo, Annalisa Grimaldi, Nicolò Baranzini, Rosangela Spiga, Elettra Mancuso, Maria Rita Rippo, Antonio Domenico Procopio, Anna Novials, Anna Rita Bonfigli, Silvia Garavelli, Lucia La Sala, Giuseppe Matarese, Paola de Candia, Fabiola Olivieri and Antonio Ceriello

Diabetes 2021 Jan; 70 (1): 240-254. https://doi.org/10.2337/db20-0199

Add to Selected Citations
Open Access
Novel Lipid Species for Detecting and Predicting Atrial Fibrillation in Patients With Type 2 Diabetes
Yow Keat Tham, Kaushala S. Jayawardana, Zahir H. Alshehry, Corey Giles, Kevin Huynh, Adam Alexander T. Smith, Jenny Y.Y. Ooi, Sophia Zoungas, Graham S. Hillis, John Chalmers, Peter J. Meikle and Julie R. McMullen

Diabetes 2021 Jan; 70 (1): 255-261. https://doi.org/10.2337/db20-0653

Add to Selected Citations

Pharmacology and Therapeutics

You have accessRestricted Access
Dapagliflozin Suppresses ER Stress and Improves Subclinical Myocardial Function in Diabetes: From Bedside to Bench
Jhih-Yuan Shih, Yu-Wen Lin, Sudeshna Fisch, Juei-Tang Cheng, Nai-Wen Kang, Chon-Seng Hong, Zhih-Cherng Chen and Wei-Ting Chang

Diabetes 2021 Jan; 70 (1): 262-267. https://doi.org/10.2337/db20-0840

Add to Selected Citations

Genetics/Genomes/Proteomics/Metabolomics

Open Access
Genetic Loci and Physiologic Pathways Involved in Gestational Diabetes Mellitus Implicated Through Clustering
Camille E. Powe, Miriam S. Udler, Sarah Hsu, Catherine Allard, Alan Kuang, Alisa K. Manning, Patrice Perron, Luigi Bouchard, William L. Lowe, Denise Scholtens, Jose C. Florez and Marie-France Hivert

Diabetes 2021 Jan; 70 (1): 268-281. https://doi.org/10.2337/db20-0772

Add to Selected Citations
You have accessRestricted Access
Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: The TEDDY Study
Qian Li, Xiang Liu, Jimin Yang, Iris Erlund, Åke Lernmark, William Hagopian, Marian Rewers, Jin-Xiong She, Jorma Toppari, Anette-G. Ziegler, Beena Akolkar, Jeffrey P. Krischer and the TEDDY Study Group

Diabetes 2021 Jan; 70 (1): 282-292. https://doi.org/10.2337/db20-0696

Add to Selected Citations
Open Access
A Polygenic Score for Type 2 Diabetes Risk Is Associated With Both the Acute and Sustained Response to Sulfonylureas
Josephine H. Li, Lukasz Szczerbinski, Adem Y. Dawed, Varinderpal Kaur, Jennifer N. Todd, Ewan R. Pearson and Jose C. Florez

Diabetes 2021 Jan; 70 (1): 293-300. https://doi.org/10.2337/db20-0530

Add to Selected Citations

Erratum

Open Access
Erratum. Abrogation of MMP-9 Gene Protects Against the Development of Retinopathy in Diabetic Mice by Preventing Mitochondrial Damage. Diabetes 2011;60:3023–3033
Renu A. Kowluru, Ghulam Mohammad, Julia M. dos Santos and Qing Zhong

Diabetes 2021 Jan; 70 (1): 301. https://doi.org/10.2337/db21-er01a

Add to Selected Citations

Issues and Events

Open Access
Issues and Events
Diabetes 2021 Jan; 70 (1): 302. https://doi.org/10.2337/db21-ie01

Add to Selected Citations

Main menu

User menu

Search

Table of Contents

Perspectives in Diabetes

Commentary

ADA Award Lectures

Metabolism

Obesity Studies

Islet Studies

Immunology and Transplantation

Pathophysiology

Complications

Pharmacology and Therapeutics

Genetics/Genomes/Proteomics/Metabolomics

Erratum

Issues and Events

In this Issue

Jump to

Navigate

More Information

Other ADA Resources