Islet Studies

Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Mice With Diet-Induced Obesity

  1. Xing Ming1,2,
  2. Arthur C.K. Chung1,
  3. Dandan Mao1,2,
  4. Huanyi Cao1,2,
  5. Baoqi Fan1,2,
  6. Willy K.K. Wong1,2,
  7. Chin Chung Ho3,
  8. Heung Man Lee1,2,4,
  9. Kristina Schoonjans5,
  10. Johan Auwerx5,
  11. Guy A. Rutter6,7,
  12. Juliana C.N. Chan1,2,4,
  13. Xiao Yu Tian3⇑ and
  14. Alice P.S. Kong1,2,4⇑
  1. 1Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
  2. 2Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China
  3. 3School of Biomedical Science, The Chinese University of Hong Kong, Hong Kong SAR, China
  4. 4Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China
  5. 5Laboratory of Integrative and Systems Physiology, School of Life Sciences, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland
  6. 6Section of Cell Biology and Functional Genomics, Imperial College of London, London, U.K.
  7. 7Lee Kong Chian School of Medicine, Nan Yang Technological University, Singapore
  1. Corresponding authors: Alice P.S. Kong, alicekong{at}cuhk.edu.hk, and Xiao Yu Tian, xytian{at}cuhk.edu.hk
Diabetes 2021 Jan; 70(1): 119-131. https://doi.org/10.2337/db20-0339

Data supplements

  • Supplemental material, Tian, et al.

    Supplemental material is available at https://doi.org/10.2337/figshare.13089923.
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    Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Mice With Diet-Induced Obesity
    Xing Ming, Arthur C.K. Chung, Dandan Mao, Huanyi Cao, Baoqi Fan, Willy K.K. Wong, Chin Chung Ho, Heung Man Lee, Kristina Schoonjans, Johan Auwerx, Guy A. Rutter, Juliana C.N. Chan, Xiao Yu Tian, Alice P.S. Kong
    Diabetes Jan 2021, 70 (1) 119-131; DOI: 10.2337/db20-0339
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