Metabolism

Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy

  1. Camille Gamblin1,
  2. Christine Rouault1,
  3. Amélie Lacombe2,
  4. Francina Langa-Vives3,
  5. Dominique Farabos4,
  6. Antonin Lamaziere4,
  7. Karine Clément1,
  8. Emmanuel L. Gautier2,
  9. Laurent Yvan-Charvet5 and
  10. Isabelle Dugail1⇑
  1. 1UMRS 1269 INSERM/Sorbonne University, Nutriomics, Paris, France
  2. 2UMRS 1166 INSERM/Sorbonne University, Paris, France
  3. 3Mouse Genetics Engineering Center, Pasteur Institute, Paris, France
  4. 4Sorbonne University INSERM, Saint Antoine Research Center, CRSA, INSERM, Département de Métabolomique Clinique, Hôpital Saint Antoine, AP-HP/Sorbonne Université, Paris, France
  5. 5UMRS 1065 INSERM/Nice Sophia Antipolis University, C3M, Nice, France
  1. Corresponding author: Isabelle Dugail, isabelle.dugail{at}inserm.fr
Diabetes 2021 Jan; 70(1): 76-90. https://doi.org/10.2337/db20-0578

Data supplements

  • Supplemental material, Dugail, et al.

    Supplemental material is available at https://doi.org/10.2337/figshare.13122758.
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    Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy
    Camille Gamblin, Christine Rouault, Amélie Lacombe, Francina Langa-Vives, Dominique Farabos, Antonin Lamaziere, Karine Clément, Emmanuel L. Gautier, Laurent Yvan-Charvet, Isabelle Dugail
    Diabetes Jan 2021, 70 (1) 76-90; DOI: 10.2337/db20-0578
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