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Online Ahead of Print

February 25, 2021

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    Low-dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report
    Andrea Lin, Jasmine A. Mack, Brittany Bruggeman, Laura M. Jacobsen, Amanda L. Posgai, Clive H. Wasserfall, Todd M. Brusko, Mark A. Atkinson, Stephen E. Gitelman, Peter A. Gottlieb, Matthew J. Gurka, Clayton E. Mathews, Desmond A Schatz and Michael J. Haller
    Diabetes February 25, 2021; db201103. https://doi.org/10.2337/db20-1103
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    The Relationship Between Glycaemia, Cognitive Function, Structural Brain Outcomes and Dementia: A Mendelian Randomisation Study in the UK Biobank
    Victoria Garfield, Aliki-Eleni Farmaki, Ghazaleh Fatemifar, Sophie V. Eastwood, Rohini Mathur, Christopher T. Rentsch, Spiros Denaxas, Krishnan Bhaskaran, Liam Smeeth and Nish Chaturvedi
    Diabetes February 25, 2021; db200895. https://doi.org/10.2337/db20-0895
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  • Open Access
    How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?
    Michael J. Haller, Laura M. Jacobsen, Amanda L. Posgai and Desmond A. Schatz
    Diabetes February 25, 2021; dbi200045. https://doi.org/10.2337/dbi20-0045
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February 24, 2021

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    Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing
    Hua Qu, Tian Miao, Yuren Wang, Liang Tan, Bangliang Huang, Linlin Zhang, Xiufei Liu, Min Long, Rui Zhang, Xiaoyu Liao, Xiaoli Gong, Ju Wang, Xin Xiong, Junli Liu, Xi Li, Jiang Yu, Gangyi Yang, Zhiming Zhu, Hongting Zheng and Yi Zheng
    Diabetes February 24, 2021; db201008. https://doi.org/10.2337/db20-1008
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    Beneficial Metabolic Effects of TREM2 in Obesity are Uncoupled from its Expression on Macrophages
    Omar Sharif, Julia Stefanie Brunner, Ana Korosec, Rui Martins, Alexander Jais, Berend Snijder, Andrea Vogel, Michael Caldera, Anastasiya Hladik, Karin Lakovits, Simona Saluzzo, Benedikta Boehm, Anna-Dorothea Gorki, Ildiko Mesteri, Josefine Lindroos-Christensen, Katharina Tillmann, Dagmar Stoiber, Jörg Menche, Gernot Schabbauer, Martin Bilban, Giulio Superti-Furga, Harald Esterbauer and Sylvia Knapp
    Diabetes February 24, 2021; db200572. https://doi.org/10.2337/db20-0572
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February 19, 2021

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    Differences in Biomarkers of Inflammation Between Novel Subgroups of Recent-Onset Diabetes
    Christian Herder, Haifa Maalmi, Klaus Strassburger, Oana-Patricia Zaharia, Jacqueline M. Ratter, Yanislava Karusheva, Mohamed A. Elhadad, Kálmán Bódis, Brenda W. C. Bongaerts, Wolfgang Rathmann, Sandra Trenkamp, Melanie Waldenberger, Volker Burkart, Julia Szendroedi and Michael Roden, GDS Group
    Diabetes February 19, 2021; db201054. https://doi.org/10.2337/db20-1054
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February 18, 2021

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    Glucokinase Inactivation Paradoxically Ameliorates Glucose Intolerance by Increasing Beta-Cell Mass in db/db Mice
    Kazuno Omori, Akinobu Nakamura, Hideaki Miyoshi, Yuki Yamauchi, Shinichiro Kawata, Kiyohiko Takahashi, Naoyuki Kitao, Hiroshi Nomoto, Hiraku Kameda, Kyu Yong Cho, Yasuo Terauchi and Tatsuya Atsumi
    Diabetes February 18, 2021; db200881. https://doi.org/10.2337/db20-0881
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February 17, 2021

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    FOXO1-mediated Downregulation of RAB27B Leads to Decreased Exosome Secretion in Diabetic Kidneys
    Mengru Zeng, Jin Wen, Zhengwei Ma, Li Xiao, Yutao Liu, Sangho Kwon, Yu Liu and Zheng Dong
    Diabetes February 17, 2021; db201108. https://doi.org/10.2337/db20-1108
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    Obesity and COVID-19 in Adult Patients With Diabetes
    Peihua Cao, Ying Song, Zian Zhuang, Jinjun Ran, Lin Xu, Yan Geng, Lefei Han, Shi Zhao, Jing Qin, Daihai He, Fengfu Wu and Lin Yang
    Diabetes February 17, 2021; db200671. https://doi.org/10.2337/db20-0671
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February 11, 2021

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    Cell-Subtype-Specific Remodeling of Intrinsically Photosensitive Retinal Ganglion Cells in Streptozotocin-Induced Diabetic Mice
    Wei-Yi Chen, Xu Han, Ling-Jie Cui, Chen-Xi Yu, Wen-Long Sheng, Jun Yu, Fei Yuan, Yong-Mei Zhong, Xiong-Li Yang and Shi-Jun Weng
    Diabetes February 11, 2021; db200775. https://doi.org/10.2337/db20-0775
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February 10, 2021

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    The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion
    Gregor Sachse, Elizabeth Haythorne, Thomas Hill, Peter Proks, Russell Joynson, Raul Terrón-Expósito, Liz Bentley, Stephen J. Tucker, Roger D. Cox and Frances M. Ashcroft
    Diabetes February 10, 2021; db200691. https://doi.org/10.2337/db20-0691
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February 09, 2021

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    Exercise Training Promotes Sex-Specific Adaptations in Mouse Inguinal White Adipose Tissue
    Pasquale Nigro, Roeland J. W. Middelbeek, Christiano R. R. Alves, Susana Rovira–Llopis, Krithika Ramachandran, Leslie A. Rowland, Andreas B. Møller, Hirokazu Takahashi, Ana B. Alves-Wagner, Maria Vamvini, Nathan S. Makarewicz, Brent G. Albertson, Michael F. Hirshman and Laurie J. Goodyear
    Diabetes February 09, 2021; db200790. https://doi.org/10.2337/db20-0790
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    Virgin Beta Cells at the Neogenic Niche Proliferate Normally and Mature Slowly
    Sharon Lee, Jing Zhang, Supraja Saravanakumar, Marcus F. Flisher, David R. Grimm, Talitha van der Meulen and Mark O. Huising
    Diabetes February 09, 2021; db200679. https://doi.org/10.2337/db20-0679
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    Lipoprotein Lipase Overexpression in Skeletal Muscle Attenuates Weight Regain by Potentiating Energy Expenditure
    David M Presby, Michael C Rudolph, Vanessa D Sherk, Matthew R Jackman, Rebecca M Foright, Kenneth L Jones, Julie A Houck, Ginger C Johnson, Janine A Higgins, P. Darrell Neufer, Robert H Eckel and Paul S MacLean
    Diabetes February 09, 2021; db200763. https://doi.org/10.2337/db20-0763
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February 05, 2021

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    The SNAG Domain of Insm1 Regulates Pancreatic Endocrine Cell Differentiation and Represses Beta- to Delta-Cell Transdifferentiation
    Xuehua Liang, Hualin Duan, Yahui Mao, Ulrich Koestner, Yiqiu Wei, Feng Deng, Jingshen Zhuang, Huimin Li, Cunchuan Wang, Luis R. Hernandez-Miranda, Weihua Tao and Shiqi Jia
    Diabetes February 05, 2021; db200883. https://doi.org/10.2337/db20-0883
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    Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor by Positron Emission Tomography
    Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Andreas Evers, Katrin Lorenz, Iina Laitinen, Philip J Larsen, Oliver Plettenburg, Lars Johansson, Stefan Pierrou and Michael Wagner
    Diabetes February 05, 2021; db201096. https://doi.org/10.2337/db20-1096
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February 02, 2021

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    Natural Protection From Type 1 Diabetes in Non Obese Diabetic (Nod) Mice is Characterised by a Unique Pancreatic Islet Phenotype
    Joanne Boldison, Terri C. Thayer, Joanne Davies and F. Susan Wong
    Diabetes February 02, 2021; db200945. https://doi.org/10.2337/db20-0945
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February 01, 2021

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    Deficits in the Skeletal Muscle Transcriptome and Mitochondrial Coupling in Progressive Diabetes-Induced CKD Relate to Functional Decline
    Daniel C. Bittel, Adam J. Bittel, Arun S. Varadhachary, Terri Pietka and David R. Sinacore
    Diabetes February 01, 2021; db200688. https://doi.org/10.2337/db20-0688
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    Syntaxin 4 Mediates NF-κB Signaling and Chemokine Ligand Expression via Specific Interaction with IκBβ
    Rajakrishnan Veluthakal, Eunjin Oh, Miwon Ahn, Diti Chatterjee-Bhowmick and Debbie C. Thurmond
    Diabetes February 01, 2021; db200868. https://doi.org/10.2337/db20-0868
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    Cell Cycle Regulation of the Pdx1 Transcription Factor in Developing Pancreas and Insulin-Producing β Cells
    Xiaogdong Zhu, Alexis Oguh, Morgan A. Gingerich, Scott A. Soleimanpour, Doris A. Stoffers and Maureen Gannon
    Diabetes February 01, 2021; db200599. https://doi.org/10.2337/db20-0599
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January 27, 2021

  • Open Access
    Erratum. Impaired Metabolic Flexibility to High-Fat Overfeeding Predicts Future Weight Gain in Healthy Adults. Diabetes 2020;69:181–192
    Brittany Begaye, Karyne L. Vinales, Tim Hollstein, Takafumi Ando, Mary Walter, Clifton Bogardus, Jonathan Krakoff and Paolo Piaggi
    Diabetes January 27, 2021; db21er04a. https://doi.org/10.2337/db21-er04a
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January 26, 2021

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    Loss of MANF causes childhood onset syndromic diabetes due to increased endoplasmic reticulum stress
    Hossam Montaser, Kashyap A Patel, Diego Balboa, Hazem Ibrahim, Väinö Lithovius, Anna Näätänen, Vikash Chandra, Korcan Demir, Sezer Acar, Tawfeg Ben-Omran, Kevin Colclough, Jonathan M. Locke, Matthew Wakeling, Maria Lindahl, Andrew Hattersley, Jonna Saarimäki-Vire and Timo Otonkoski
    Diabetes January 26, 2021; db201174. https://doi.org/10.2337/db20-1174
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January 21, 2021

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    Impaired Activated/Memory Regulatory T Cell Clonal Expansion Instigates Diabetes in NOD Mice
    Vanessa Mhanna, Gwladys Fourcade, Pierre Barennes, Valentin Quiniou, Hang P. Pham, Paul-Gydeon Ritvo, Faustine Brimaud, Bruno Gouritin, Guillaume Churlaud, Adrien Six, Encarnita Mariotti-Ferrandiz and David Klatzmann
    Diabetes January 21, 2021; db200896. https://doi.org/10.2337/db20-0896
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    Longitudinal Assessment of 11C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes
    Daniel Espes, Per-Ola Carlsson, Ram Kumar Selvaraju, Maria Rosestedt, Pierre Cheung, Håkan Ahlström, Olle Korsgren and Olof Eriksson
    Diabetes January 21, 2021; db200776. https://doi.org/10.2337/db20-0776
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    The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium
    Shylaja Srinivasan, Ling Chen, Jennifer Todd, Jasmin Divers, Samuel Gidding, Steven Chernausek, Rose A. Gubitosi-Klug, Megan M. Kelsey, Rachana Shah, Mary Helen Black, Lynne E. Wagenknecht, Alisa Manning, Jason Flannick, Giuseppina Imperatore, Josep M. Mercader, Dana Dabelea, Jose C. Florez and on behalf of the ProDiGY Consortium.
    Diabetes January 21, 2021; db200443. https://doi.org/10.2337/db20-0443
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January 19, 2021

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    Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes
    Rebuma Firdessa-Fite, Stephanie N. Johnson, Martin A. Leon, Mohsen Khosravi-Maharlooei, Rocky L. Baker, Joshua O. Sestak, Cory Berkland and Remi J. Creusot
    Diabetes January 19, 2021; db200845. https://doi.org/10.2337/db20-0845
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    Dynamic uni- and Multicellular Patterns Encode Biphasic Activity in Pancreatic Islets
    Manon Jaffredo, Eléonore Bertin, Antoine Pirog, Emilie Puginier, Julien Gaitan, Sandra Oucherif, Fanny Lebreton, Domenico Bosco, Bogdan Catargi, Daniel Cattaert, Sylvie Renaud, Jochen Lang and Matthieu Raoux
    Diabetes January 19, 2021; db200214. https://doi.org/10.2337/db20-0214
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January 13, 2021

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    Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size
    James J. Ross, Clive H. Wasserfall, Rhonda Bacher, Daniel J. Perry, Kieran McGrail, Amanda L. Posgai, Xiaoru Dong, Andrew Muir, Xia Li, Martha Campbell-Thompson, Todd M. Brusko, Desmond A. Schatz, Michael J. Haller and Mark A. Atkinson
    Diabetes January 13, 2021; db200995. https://doi.org/10.2337/db20-0995
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January 11, 2021

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    Lifestyle Intervention in Pregnant Women With Obesity Impacts Cord Blood DNA Methylation Which Associates With Body Composition in the Offspring
    Josefine Jönsson, Kristina M. Renault, Sonia García-Calzón, Alexander Perfilyev, Angela C. Estampador, Kirsten Nørgaard, Mads Vendelbo Lind, Allan Vaag, Line Hjort, Kim F. Michaelsen, Emma Malchau Carlsen, Paul W. Franks and Charlotte Ling
    Diabetes January 11, 2021; db200487. https://doi.org/10.2337/db20-0487
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January 08, 2021

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    Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis
    MacKenzie D. Williams, Rhonda Bacher, Daniel J. Perry, C. Ramsey Grace, Kieran M. McGrail, Amanda L. Posgai, Andrew Muir, Srikar Chamala, Michael J. Haller, Desmond A. Schatz, Todd M. Brusko, Mark A. Atkinson and Clive H. Wasserfall
    Diabetes January 08, 2021; db200937. https://doi.org/10.2337/db20-0937
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January 07, 2021

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    Novel Linkage Peaks Discovered for Diabetic Nephropathy in Individuals With Type 1 Diabetes
    Jani Haukka, Niina Sandholm, Erkka Valo, Carol Forsblom, Valma Harjutsalo, Joanne B. Cole, Stuart J. McGurnaghan, Helen M. Colhoun and Per-Henrik Groop, on behalf of the FinnDiane Study Group
    Diabetes January 07, 2021; db200158. https://doi.org/10.2337/db20-0158
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November 17, 2020

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    circRNA_010383 Acts as a Sponge for miR-135a and its Downregulated Expression Contributes to Renal Fibrosis in Diabetic Nephropathy
    Fenfen Peng, Wangqiu Gong, Shuting Li, Bohui Yin, Chen Zhao, Wenting Liu, Xiaowen Chen, Congwei Luo, Qianying Huang, Ting Chen, Lingzhi Sun, Shun Fang, Weidong Zhou, Zhijian Li and Haibo Long
    Diabetes November 17, 2020; db200203. https://doi.org/10.2337/db200203
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Diabetes: 70 (3)

Current Issue

March 2021
Volume 70, Issue 3

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  • Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis
  • Latent Autoimmune Diabetes in Adults
  • Poverty and Obesity in the U.S.
  • The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion
  • A Polymorphism in the Glucocorticoid Receptor Gene, Which Decreases Sensitivity to Glucocorticoids In Vivo, Is Associated With Low Insulin and Cholesterol Levels
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