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February 25, 2021

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Low-dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report
Andrea Lin, Jasmine A. Mack, Brittany Bruggeman, Laura M. Jacobsen, Amanda L. Posgai, Clive H. Wasserfall, Todd M. Brusko, Mark A. Atkinson, Stephen E. Gitelman, Peter A. Gottlieb, Matthew J. Gurka, Clayton E. Mathews, Desmond A Schatz and Michael J. Haller

Diabetes February 25, 2021; db201103. https://doi.org/10.2337/db20-1103

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The Relationship Between Glycaemia, Cognitive Function, Structural Brain Outcomes and Dementia: A Mendelian Randomisation Study in the UK Biobank
Victoria Garfield, Aliki-Eleni Farmaki, Ghazaleh Fatemifar, Sophie V. Eastwood, Rohini Mathur, Christopher T. Rentsch, Spiros Denaxas, Krishnan Bhaskaran, Liam Smeeth and Nish Chaturvedi

Diabetes February 25, 2021; db200895. https://doi.org/10.2337/db20-0895

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Open Access
How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?
Michael J. Haller, Laura M. Jacobsen, Amanda L. Posgai and Desmond A. Schatz

Diabetes February 25, 2021; dbi200045. https://doi.org/10.2337/dbi20-0045

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February 24, 2021

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Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing
Hua Qu, Tian Miao, Yuren Wang, Liang Tan, Bangliang Huang, Linlin Zhang, Xiufei Liu, Min Long, Rui Zhang, Xiaoyu Liao, Xiaoli Gong, Ju Wang, Xin Xiong, Junli Liu, Xi Li, Jiang Yu, Gangyi Yang, Zhiming Zhu, Hongting Zheng and Yi Zheng

Diabetes February 24, 2021; db201008. https://doi.org/10.2337/db20-1008

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Beneficial Metabolic Effects of TREM2 in Obesity are Uncoupled from its Expression on Macrophages
Omar Sharif, Julia Stefanie Brunner, Ana Korosec, Rui Martins, Alexander Jais, Berend Snijder, Andrea Vogel, Michael Caldera, Anastasiya Hladik, Karin Lakovits, Simona Saluzzo, Benedikta Boehm, Anna-Dorothea Gorki, Ildiko Mesteri, Josefine Lindroos-Christensen, Katharina Tillmann, Dagmar Stoiber, Jörg Menche, Gernot Schabbauer, Martin Bilban, Giulio Superti-Furga, Harald Esterbauer and Sylvia Knapp

Diabetes February 24, 2021; db200572. https://doi.org/10.2337/db20-0572

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February 19, 2021

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Differences in Biomarkers of Inflammation Between Novel Subgroups of Recent-Onset Diabetes
Christian Herder, Haifa Maalmi, Klaus Strassburger, Oana-Patricia Zaharia, Jacqueline M. Ratter, Yanislava Karusheva, Mohamed A. Elhadad, Kálmán Bódis, Brenda W. C. Bongaerts, Wolfgang Rathmann, Sandra Trenkamp, Melanie Waldenberger, Volker Burkart, Julia Szendroedi and Michael Roden, GDS Group

Diabetes February 19, 2021; db201054. https://doi.org/10.2337/db20-1054

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February 18, 2021

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Glucokinase Inactivation Paradoxically Ameliorates Glucose Intolerance by Increasing Beta-Cell Mass in db/db Mice
Kazuno Omori, Akinobu Nakamura, Hideaki Miyoshi, Yuki Yamauchi, Shinichiro Kawata, Kiyohiko Takahashi, Naoyuki Kitao, Hiroshi Nomoto, Hiraku Kameda, Kyu Yong Cho, Yasuo Terauchi and Tatsuya Atsumi

Diabetes February 18, 2021; db200881. https://doi.org/10.2337/db20-0881

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February 17, 2021

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FOXO1-mediated Downregulation of RAB27B Leads to Decreased Exosome Secretion in Diabetic Kidneys
Mengru Zeng, Jin Wen, Zhengwei Ma, Li Xiao, Yutao Liu, Sangho Kwon, Yu Liu and Zheng Dong

Diabetes February 17, 2021; db201108. https://doi.org/10.2337/db20-1108

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Obesity and COVID-19 in Adult Patients With Diabetes
Peihua Cao, Ying Song, Zian Zhuang, Jinjun Ran, Lin Xu, Yan Geng, Lefei Han, Shi Zhao, Jing Qin, Daihai He, Fengfu Wu and Lin Yang

Diabetes February 17, 2021; db200671. https://doi.org/10.2337/db20-0671

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February 11, 2021

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Cell-Subtype-Specific Remodeling of Intrinsically Photosensitive Retinal Ganglion Cells in Streptozotocin-Induced Diabetic Mice
Wei-Yi Chen, Xu Han, Ling-Jie Cui, Chen-Xi Yu, Wen-Long Sheng, Jun Yu, Fei Yuan, Yong-Mei Zhong, Xiong-Li Yang and Shi-Jun Weng

Diabetes February 11, 2021; db200775. https://doi.org/10.2337/db20-0775

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February 10, 2021

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The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion
Gregor Sachse, Elizabeth Haythorne, Thomas Hill, Peter Proks, Russell Joynson, Raul Terrón-Expósito, Liz Bentley, Stephen J. Tucker, Roger D. Cox and Frances M. Ashcroft

Diabetes February 10, 2021; db200691. https://doi.org/10.2337/db20-0691

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February 09, 2021

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Exercise Training Promotes Sex-Specific Adaptations in Mouse Inguinal White Adipose Tissue
Pasquale Nigro, Roeland J. W. Middelbeek, Christiano R. R. Alves, Susana Rovira–Llopis, Krithika Ramachandran, Leslie A. Rowland, Andreas B. Møller, Hirokazu Takahashi, Ana B. Alves-Wagner, Maria Vamvini, Nathan S. Makarewicz, Brent G. Albertson, Michael F. Hirshman and Laurie J. Goodyear

Diabetes February 09, 2021; db200790. https://doi.org/10.2337/db20-0790

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Virgin Beta Cells at the Neogenic Niche Proliferate Normally and Mature Slowly
Sharon Lee, Jing Zhang, Supraja Saravanakumar, Marcus F. Flisher, David R. Grimm, Talitha van der Meulen and Mark O. Huising

Diabetes February 09, 2021; db200679. https://doi.org/10.2337/db20-0679

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Lipoprotein Lipase Overexpression in Skeletal Muscle Attenuates Weight Regain by Potentiating Energy Expenditure
David M Presby, Michael C Rudolph, Vanessa D Sherk, Matthew R Jackman, Rebecca M Foright, Kenneth L Jones, Julie A Houck, Ginger C Johnson, Janine A Higgins, P. Darrell Neufer, Robert H Eckel and Paul S MacLean

Diabetes February 09, 2021; db200763. https://doi.org/10.2337/db20-0763

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February 05, 2021

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The SNAG Domain of Insm1 Regulates Pancreatic Endocrine Cell Differentiation and Represses Beta- to Delta-Cell Transdifferentiation
Xuehua Liang, Hualin Duan, Yahui Mao, Ulrich Koestner, Yiqiu Wei, Feng Deng, Jingshen Zhuang, Huimin Li, Cunchuan Wang, Luis R. Hernandez-Miranda, Weihua Tao and Shiqi Jia

Diabetes February 05, 2021; db200883. https://doi.org/10.2337/db20-0883

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Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor by Positron Emission Tomography
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Andreas Evers, Katrin Lorenz, Iina Laitinen, Philip J Larsen, Oliver Plettenburg, Lars Johansson, Stefan Pierrou and Michael Wagner

Diabetes February 05, 2021; db201096. https://doi.org/10.2337/db20-1096

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January 26, 2021

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Loss of MANF causes childhood onset syndromic diabetes due to increased endoplasmic reticulum stress
Hossam Montaser, Kashyap A Patel, Diego Balboa, Hazem Ibrahim, Väinö Lithovius, Anna Näätänen, Vikash Chandra, Korcan Demir, Sezer Acar, Tawfeg Ben-Omran, Kevin Colclough, Jonathan M. Locke, Matthew Wakeling, Maria Lindahl, Andrew Hattersley, Jonna Saarimäki-Vire and Timo Otonkoski

Diabetes January 26, 2021; db201174. https://doi.org/10.2337/db20-1174

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January 21, 2021

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Impaired Activated/Memory Regulatory T Cell Clonal Expansion Instigates Diabetes in NOD Mice
Vanessa Mhanna, Gwladys Fourcade, Pierre Barennes, Valentin Quiniou, Hang P. Pham, Paul-Gydeon Ritvo, Faustine Brimaud, Bruno Gouritin, Guillaume Churlaud, Adrien Six, Encarnita Mariotti-Ferrandiz and David Klatzmann

Diabetes January 21, 2021; db200896. https://doi.org/10.2337/db20-0896

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Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes
Daniel Espes, Per-Ola Carlsson, Ram Kumar Selvaraju, Maria Rosestedt, Pierre Cheung, Håkan Ahlström, Olle Korsgren and Olof Eriksson

Diabetes January 21, 2021; db200776. https://doi.org/10.2337/db20-0776

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The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium
Shylaja Srinivasan, Ling Chen, Jennifer Todd, Jasmin Divers, Samuel Gidding, Steven Chernausek, Rose A. Gubitosi-Klug, Megan M. Kelsey, Rachana Shah, Mary Helen Black, Lynne E. Wagenknecht, Alisa Manning, Jason Flannick, Giuseppina Imperatore, Josep M. Mercader, Dana Dabelea, Jose C. Florez and on behalf of the ProDiGY Consortium.

Diabetes January 21, 2021; db200443. https://doi.org/10.2337/db20-0443

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January 19, 2021

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Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes
Rebuma Firdessa-Fite, Stephanie N. Johnson, Martin A. Leon, Mohsen Khosravi-Maharlooei, Rocky L. Baker, Joshua O. Sestak, Cory Berkland and Remi J. Creusot

Diabetes January 19, 2021; db200845. https://doi.org/10.2337/db20-0845

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Dynamic uni- and Multicellular Patterns Encode Biphasic Activity in Pancreatic Islets
Manon Jaffredo, Eléonore Bertin, Antoine Pirog, Emilie Puginier, Julien Gaitan, Sandra Oucherif, Fanny Lebreton, Domenico Bosco, Bogdan Catargi, Daniel Cattaert, Sylvie Renaud, Jochen Lang and Matthieu Raoux

Diabetes January 19, 2021; db200214. https://doi.org/10.2337/db20-0214

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January 13, 2021

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Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size
James J. Ross, Clive H. Wasserfall, Rhonda Bacher, Daniel J. Perry, Kieran McGrail, Amanda L. Posgai, Xiaoru Dong, Andrew Muir, Xia Li, Martha Campbell-Thompson, Todd M. Brusko, Desmond A. Schatz, Michael J. Haller and Mark A. Atkinson

Diabetes January 13, 2021; db200995. https://doi.org/10.2337/db20-0995

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January 11, 2021

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Lifestyle Intervention in Pregnant Women With Obesity Impacts Cord Blood DNA Methylation Which Associates With Body Composition in the Offspring
Josefine Jönsson, Kristina M. Renault, Sonia García-Calzón, Alexander Perfilyev, Angela C. Estampador, Kirsten Nørgaard, Mads Vendelbo Lind, Allan Vaag, Line Hjort, Kim F. Michaelsen, Emma Malchau Carlsen, Paul W. Franks and Charlotte Ling

Diabetes January 11, 2021; db200487. https://doi.org/10.2337/db20-0487

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January 08, 2021

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Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis
MacKenzie D. Williams, Rhonda Bacher, Daniel J. Perry, C. Ramsey Grace, Kieran M. McGrail, Amanda L. Posgai, Andrew Muir, Srikar Chamala, Michael J. Haller, Desmond A. Schatz, Todd M. Brusko, Mark A. Atkinson and Clive H. Wasserfall

Diabetes January 08, 2021; db200937. https://doi.org/10.2337/db20-0937

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January 07, 2021

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Novel Linkage Peaks Discovered for Diabetic Nephropathy in Individuals With Type 1 Diabetes
Jani Haukka, Niina Sandholm, Erkka Valo, Carol Forsblom, Valma Harjutsalo, Joanne B. Cole, Stuart J. McGurnaghan, Helen M. Colhoun and Per-Henrik Groop, on behalf of the FinnDiane Study Group

Diabetes January 07, 2021; db200158. https://doi.org/10.2337/db20-0158

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November 17, 2020

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circRNA_010383 Acts as a Sponge for miR-135a and its Downregulated Expression Contributes to Renal Fibrosis in Diabetic Nephropathy
Fenfen Peng, Wangqiu Gong, Shuting Li, Bohui Yin, Chen Zhao, Wenting Liu, Xiaowen Chen, Congwei Luo, Qianying Huang, Ting Chen, Lingzhi Sun, Shun Fang, Weidong Zhou, Zhijian Li and Haibo Long

Diabetes November 17, 2020; db200203. https://doi.org/10.2337/db200203

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