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April 13, 2021

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A transcription start site map in human pancreatic islets reveals functional regulatory signatures
Arushi Varshney, Yasuhiro Kyono, Venkateswaran Ramamoorthi Elangovan, Collin Wang, Michael R. Erdos, Narisu Narisu, Ricardo D'Oliveira Albanus, Peter Orchard, Michael L. Stitzel, Francis S. Collins, Jacob O. Kitzman and Stephen C. J. Parker

Diabetes April 13, 2021; db201087. https://doi.org/10.2337/db20-1087

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Metformin’s Therapeutic Action in the Treatment of Diabetes Does Not Involve Inhibition of Mitochondrial Glycerol Phosphate Dehydrogenase
Michael J. MacDonald, Israr-ul H. Ansari, Melissa J. Longacre and Scott W. Stoker

Diabetes April 13, 2021; db201143. https://doi.org/10.2337/db20-1143

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April 05, 2021

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DNA methylation GrimAge and Incident Diabetes: The Coronary Artery Risk Development in Young Adults (CARDIA) Study
Kyeezu Kim, Brian Joyce, Yinan Zheng, Pamela J Schreiner, David R. Jacobs, Janet M. Catov, James M. Shikany, Mercedes R Carnethon, Philip Greenland, Linda Van Horn, Norrina Bai Allen, Donald Lloyd-Jones, Erica P. Gunderson and Lifang Hou

Diabetes April 05, 2021; db201167. https://doi.org/10.2337/db20-1167

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Overexpression of Nrf2 in Renal Proximal Tubular Cells Stimulates Sodium-Glucose Co-Transporter 2 Expression and Exacerbates Dysglycemia and Kidney Injury in Diabetic Mice
Shuiling Zhao, Chao-Sheng Lo, Kana Miyata, Anindya Ghosh, Xinping Zhao, Isabelle Chenier, Jean-Francois Cailhier, Jean Ethier, Jean-Baptiste Lattouf, Janos G Filep, Julie R Ingelfinger, Shao-Ling Zhang and John S. D. Chan

Diabetes April 05, 2021; db201126. https://doi.org/10.2337/db20-1126

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April 01, 2021

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DOT1L regulates thermogenic adipocyte differentiation and function via modulating H3K79 methylation
Lin Shuai, Bo-Han Li, Hao-Wen Jiang, Lin Yang, Jia Li and Jing-Ya Li

Diabetes April 01, 2021; db201110. https://doi.org/10.2337/db20-1110

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March 23, 2021

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The importance of the mechanisms by which insulin regulates meal-associated liver glucose uptake in the dog
Guillaume Kraft, Katie C. Coate, Marta Smith, Ben Farmer, Melanie Scott, Alan D. Cherrington and Dale S Edgerton

Diabetes March 23, 2021; db201271. https://doi.org/10.2337/db20-1271

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March 19, 2021

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Deficiency of mitochondrial glycerol 3-phosphate dehydrogenase exacerbates podocyte injury and the progression of diabetic kidney disease
Hua Qu, Xiaoli Gong, Xiufei Liu, Rui Zhang, Yuren Wang, Bangliang Huang, Linlin Zhang, Hongting Zheng and Yi Zheng

Diabetes March 19, 2021; db201157. https://doi.org/10.2337/db20-1157

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March 18, 2021

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Nanopore 16S amplicon sequencing enhances the understanding of pathogens in medically intractable diabetic foot infections
Jangsup Moon, Narae Kim, Han Sang Lee, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Sang Kun Lee, Dong-Oh Lee, Dong Yeon Lee and Kon Chu

Diabetes March 18, 2021; db200907. https://doi.org/10.2337/db20-0907

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T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes.
Josephine M. Forbes, Domenica A. McCarthy, Andrew J. Kassianos, Tracey Baskerville, Amelia J. Fotheringham, Kurt T.K. Giuliani, Anca Grivei, Andrew J. Murphy, Michelle C. Flynn, Mitchell A. Sullivan, Preeti Chandrashekar, Rani Whiddett, Kristen J. Radford, Nicole Flemming, Sam S. Beard, Neisha D’Silva, Janelle Nisbet, Adam Morton, Stephanie Teasdale, Anthony Russell, Nicole Isbel, Timothy Jones, Jennifer Couper, Helen Healy, Mark Harris, Kim Donaghue, David W. Johnson, Andrew Cotterill, Helen L. Barrett and Trisha O’Moore-Sullivan

Diabetes March 18, 2021; db201081. https://doi.org/10.2337/db20-1081

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Adiponectin Alleviates Diet-induced Inflammation in the Liver by Suppressing MCP-1 Expression and Macrophage Infiltration
Jiyoon Ryu, Jason T. Hadley, Zhi Li, Feng Dong, Huan Xu, Xiaoban Xin, Ye Zhang, Cang Chen, Senlin Li, Xiaoning Guo, Jared L. Zhao, Robin J. Leach, Muhammad A. Abdul-Ghani, Ralph A. DeFronzo, Amrita Kamat, Feng Liu and Lily Q. Dong

Diabetes March 18, 2021; db201073. https://doi.org/10.2337/db20-1073

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March 04, 2021

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Effects of Gastric Bypass Surgery on the Brain; Simultaneous Assessment of Glucose Uptake, Blood Flow, Neural Activity and Cognitive Function during Normo- and Hypoglycemia
Kristina E. Almby, Martin H. Lundqvist, Niclas Abrahamsson, Sofia Kvernby, Markus Fahlström, Maria J. Pereira, Malin Gingnell, F. Anders Karlsson, Giovanni Fanni, Magnus Sundbom, Urban Wiklund, Sven Haller, Mark Lubberink, Johan Wikström and Jan W. Eriksson

Diabetes March 04, 2021; db201172. https://doi.org/10.2337/db20-1172

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February 25, 2021

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Low-dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report
Andrea Lin, Jasmine A. Mack, Brittany Bruggeman, Laura M. Jacobsen, Amanda L. Posgai, Clive H. Wasserfall, Todd M. Brusko, Mark A. Atkinson, Stephen E. Gitelman, Peter A. Gottlieb, Matthew J. Gurka, Clayton E. Mathews, Desmond A Schatz and Michael J. Haller

Diabetes February 25, 2021; db201103. https://doi.org/10.2337/db20-1103

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The Relationship Between Glycaemia, Cognitive Function, Structural Brain Outcomes and Dementia: A Mendelian Randomisation Study in the UK Biobank
Victoria Garfield, Aliki-Eleni Farmaki, Ghazaleh Fatemifar, Sophie V. Eastwood, Rohini Mathur, Christopher T. Rentsch, Spiros Denaxas, Krishnan Bhaskaran, Liam Smeeth and Nish Chaturvedi

Diabetes February 25, 2021; db200895. https://doi.org/10.2337/db20-0895

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Open Access
How Do We Move Type 1 Diabetes Immunotherapies Forward During the Current COVID-19 Pandemic?
Michael J. Haller, Laura M. Jacobsen, Amanda L. Posgai and Desmond A. Schatz

Diabetes February 25, 2021; dbi200045. https://doi.org/10.2337/dbi20-0045

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February 24, 2021

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Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing
Hua Qu, Tian Miao, Yuren Wang, Liang Tan, Bangliang Huang, Linlin Zhang, Xiufei Liu, Min Long, Rui Zhang, Xiaoyu Liao, Xiaoli Gong, Ju Wang, Xin Xiong, Junli Liu, Xi Li, Jiang Yu, Gangyi Yang, Zhiming Zhu, Hongting Zheng and Yi Zheng

Diabetes February 24, 2021; db201008. https://doi.org/10.2337/db20-1008

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Beneficial Metabolic Effects of TREM2 in Obesity are Uncoupled from its Expression on Macrophages
Omar Sharif, Julia Stefanie Brunner, Ana Korosec, Rui Martins, Alexander Jais, Berend Snijder, Andrea Vogel, Michael Caldera, Anastasiya Hladik, Karin Lakovits, Simona Saluzzo, Benedikta Boehm, Anna-Dorothea Gorki, Ildiko Mesteri, Josefine Lindroos-Christensen, Katharina Tillmann, Dagmar Stoiber, Jörg Menche, Gernot Schabbauer, Martin Bilban, Giulio Superti-Furga, Harald Esterbauer and Sylvia Knapp

Diabetes February 24, 2021; db200572. https://doi.org/10.2337/db20-0572

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February 19, 2021

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Differences in Biomarkers of Inflammation Between Novel Subgroups of Recent-Onset Diabetes
Christian Herder, Haifa Maalmi, Klaus Strassburger, Oana-Patricia Zaharia, Jacqueline M. Ratter, Yanislava Karusheva, Mohamed A. Elhadad, Kálmán Bódis, Brenda W. C. Bongaerts, Wolfgang Rathmann, Sandra Trenkamp, Melanie Waldenberger, Volker Burkart, Julia Szendroedi and Michael Roden, GDS Group

Diabetes February 19, 2021; db201054. https://doi.org/10.2337/db20-1054

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February 17, 2021

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FOXO1-mediated Downregulation of RAB27B Leads to Decreased Exosome Secretion in Diabetic Kidneys
Mengru Zeng, Jin Wen, Zhengwei Ma, Li Xiao, Yutao Liu, Sangho Kwon, Yu Liu and Zheng Dong

Diabetes February 17, 2021; db201108. https://doi.org/10.2337/db20-1108

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Obesity and COVID-19 in Adult Patients With Diabetes
Peihua Cao, Ying Song, Zian Zhuang, Jinjun Ran, Lin Xu, Yan Geng, Lefei Han, Shi Zhao, Jing Qin, Daihai He, Fengfu Wu and Lin Yang

Diabetes February 17, 2021; db200671. https://doi.org/10.2337/db20-0671

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February 11, 2021

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Cell-Subtype-Specific Remodeling of Intrinsically Photosensitive Retinal Ganglion Cells in Streptozotocin-Induced Diabetic Mice
Wei-Yi Chen, Xu Han, Ling-Jie Cui, Chen-Xi Yu, Wen-Long Sheng, Jun Yu, Fei Yuan, Yong-Mei Zhong, Xiong-Li Yang and Shi-Jun Weng

Diabetes February 11, 2021; db200775. https://doi.org/10.2337/db20-0775

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February 10, 2021

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The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion
Gregor Sachse, Elizabeth Haythorne, Thomas Hill, Peter Proks, Russell Joynson, Raul Terrón-Expósito, Liz Bentley, Stephen J. Tucker, Roger D. Cox and Frances M. Ashcroft

Diabetes February 10, 2021; db200691. https://doi.org/10.2337/db20-0691

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February 09, 2021

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Exercise Training Promotes Sex-Specific Adaptations in Mouse Inguinal White Adipose Tissue
Pasquale Nigro, Roeland J. W. Middelbeek, Christiano R. R. Alves, Susana Rovira–Llopis, Krithika Ramachandran, Leslie A. Rowland, Andreas B. Møller, Hirokazu Takahashi, Ana B. Alves-Wagner, Maria Vamvini, Nathan S. Makarewicz, Brent G. Albertson, Michael F. Hirshman and Laurie J. Goodyear

Diabetes February 09, 2021; db200790. https://doi.org/10.2337/db20-0790

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Virgin Beta Cells at the Neogenic Niche Proliferate Normally and Mature Slowly
Sharon Lee, Jing Zhang, Supraja Saravanakumar, Marcus F. Flisher, David R. Grimm, Talitha van der Meulen and Mark O. Huising

Diabetes February 09, 2021; db200679. https://doi.org/10.2337/db20-0679

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February 05, 2021

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The SNAG Domain of Insm1 Regulates Pancreatic Endocrine Cell Differentiation and Represses Beta- to Delta-Cell Transdifferentiation
Xuehua Liang, Hualin Duan, Yahui Mao, Ulrich Koestner, Yiqiu Wei, Feng Deng, Jingshen Zhuang, Huimin Li, Cunchuan Wang, Luis R. Hernandez-Miranda, Weihua Tao and Shiqi Jia

Diabetes February 05, 2021; db200883. https://doi.org/10.2337/db20-0883

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February 01, 2021

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Deficits in the Skeletal Muscle Transcriptome and Mitochondrial Coupling in Progressive Diabetes-Induced CKD Relate to Functional Decline
Daniel C. Bittel, Adam J. Bittel, Arun S. Varadhachary, Terri Pietka and David R. Sinacore

Diabetes February 01, 2021; db200688. https://doi.org/10.2337/db20-0688

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January 19, 2021

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Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes
Rebuma Firdessa-Fite, Stephanie N. Johnson, Martin A. Leon, Mohsen Khosravi-Maharlooei, Rocky L. Baker, Joshua O. Sestak, Cory Berkland and Remi J. Creusot

Diabetes January 19, 2021; db200845. https://doi.org/10.2337/db20-0845

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