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Research ArticleGenetics/Genomes/Proteomics/Metabolomics
Open Access

Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families

Markus Hippich, Andreas Beyerlein, William A. Hagopian, Jeffrey P. Krischer, Kendra Vehik, Jan Knoop, Christiane Winker, Jorma Toppari, Åke Lernmark, Marian J. Rewers, Andrea K. Steck, Jin-Xiong She, Beena Akolkar, Catherine C. Robertson, Suna Onengut-Gumuscu, Stephen S. Rich, Ezio Bonifacio, Anette-G. Ziegler, the TEDDY Study Group
DOI: 10.2337/db18-0882 Published 1 April 2019
Markus Hippich
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
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Andreas Beyerlein
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
2Forschergruppe Diabetes, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
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  • ORCID record for Andreas Beyerlein
William A. Hagopian
3Pacific Northwest Research Institute, Seattle, WA
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Jeffrey P. Krischer
4Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL
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Kendra Vehik
4Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL
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Jan Knoop
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
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Christiane Winker
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
5Forschergruppe Diabetes e.V., Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
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Jorma Toppari
6Department of Pediatrics, Turku University Hospital, and Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland
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Åke Lernmark
7Department of Clinical Sciences, Lund University/CRC, Skåne University Hospital SUS, Malmo, Sweden
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Marian J. Rewers
8Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO
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Andrea K. Steck
8Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO
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Jin-Xiong She
9Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University, Augusta, GA
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Beena Akolkar
10National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
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Catherine C. Robertson
11Center for Public Health Genomics, University of Virginia, Charlottesville, VA
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Suna Onengut-Gumuscu
11Center for Public Health Genomics, University of Virginia, Charlottesville, VA
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Stephen S. Rich
11Center for Public Health Genomics, University of Virginia, Charlottesville, VA
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Ezio Bonifacio
5Forschergruppe Diabetes e.V., Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
12DFG Center for Regenerative Therapies Dresden, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany
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  • For correspondence: anette-g.ziegler@helmholtz-muenchen.de ezio.bonifacio@tu-dresden.de
Anette-G. Ziegler
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
2Forschergruppe Diabetes, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
5Forschergruppe Diabetes e.V., Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
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  • ORCID record for Anette-G. Ziegler
  • For correspondence: anette-g.ziegler@helmholtz-muenchen.de ezio.bonifacio@tu-dresden.de

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