Research ArticleGenetics/Genomes/Proteomics/Metabolomics
Open Access
Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families
Markus Hippich, Andreas Beyerlein, William A. Hagopian, Jeffrey P. Krischer, Kendra Vehik, Jan Knoop, Christiane Winker, Jorma Toppari, Åke Lernmark, Marian J. Rewers, Andrea K. Steck, Jin-Xiong She, Beena Akolkar, Catherine C. Robertson, Suna Onengut-Gumuscu, Stephen S. Rich, Ezio Bonifacio, Anette-G. Ziegler, the TEDDY Study Group
DOI: 10.2337/db18-0882 Published 1 April 2019
Markus Hippich
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
Andreas Beyerlein
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany2Forschergruppe Diabetes, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
William A. Hagopian
3Pacific Northwest Research Institute, Seattle, WA
Jeffrey P. Krischer
4Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL
Kendra Vehik
4Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL
Jan Knoop
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
Christiane Winker
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany5Forschergruppe Diabetes e.V., Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany
Jorma Toppari
6Department of Pediatrics, Turku University Hospital, and Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland
Åke Lernmark
7Department of Clinical Sciences, Lund University/CRC, Skåne University Hospital SUS, Malmo, Sweden
Marian J. Rewers
8Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO
Andrea K. Steck
8Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO
Jin-Xiong She
9Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University, Augusta, GA
Beena Akolkar
10National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
Catherine C. Robertson
11Center for Public Health Genomics, University of Virginia, Charlottesville, VA
Suna Onengut-Gumuscu
11Center for Public Health Genomics, University of Virginia, Charlottesville, VA
Stephen S. Rich
11Center for Public Health Genomics, University of Virginia, Charlottesville, VA
Ezio Bonifacio
5Forschergruppe Diabetes e.V., Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany12DFG Center for Regenerative Therapies Dresden, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany
Anette-G. Ziegler
1Institute of Diabetes Research, Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany2Forschergruppe Diabetes, Klinikum rechts der Isar, Technical University Munich, Munich, Germany5Forschergruppe Diabetes e.V., Helmholtz Zentrum München (German Research Center for Environmental Health), Munich-Neuherberg, Germany