PT  - JOURNAL ARTICLE
AU  - Koenig, Ronald J
AU  - Peterson, Charles M
AU  - Kilo, Charle
AU  - Cerami, Anthony
AU  - Williamson, Joseph R
TI  - Hemoglobin A<sub>Ic</sub> as an indicator of the degree of glucose intolerance in diabetes
AID  - 10.2337/diab.25.3.230
DP  - 1976 Mar 01
TA  - Diabetes
PG  - 230--232
VI  - 25
IP  - 3
4099  - http://diabetes.diabetesjournals.org/content/25/3/230.short
4100  - http://diabetes.diabetesjournals.org/content/25/3/230.full
SO  - Diabetes1976 Mar 01; 25
AB  - Hemoglobin AIc concentration, fasting blood sugar, response to an oral glucose tolerance test, and skeletal muscle capillary basement membrane thickness were measured in diabetic patients. Hemoglobin AIc concentration correlates with both response to a glucose tolerance test (r = 0.82, p < 0.001) and fasting blood sugar (r = 0.62, p < 0.001). The correlation of hemoglobin AIc concentration with glucose tolerance is independent of fasting blood sugar concentration (partial r = 0.61, p < 0.005), whereas that of hemoglobin AIc with fasting blood sugar probably reflects the relationship between fasting blood sugar levels and glucose tolerance (partial r = 0.22, p < 0.05). Hemoglobin AIc levels do not correlate with basement membrane thickness (r = 0.15, p < 0.05).